Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Thomas Kerkau"'
Autor:
Caroline Morbach, Niklas Beyersdorf, Nicola Moser, Dora Pelin, Boshra Afshar, Gustavo Ramos, Thomas Kerkau, Elisa Kaiser, Janna Lamers, Jannika Pätkau, Floran Sahiti, Judith Albert, Gülmisal Güder, Georg Ertl, Christiane E. Angermann, Stefan Frantz, Ulrich Hofmann, Roland Jahns, Valerie Jahns, Stefan Störk
Publikováno v:
ESC Heart Failure, Vol 10, Iss 5, Pp 3227-3231 (2023)
Abstract Aims Agonistic antibodies against neurohumoral receptors can induce cardio‐noxious effects by altering the baseline receptor activity. To estimate the prevalence of autoantibodies directed against the beta‐1 receptor (b1‐AAB) in patien
Externí odkaz:
https://doaj.org/article/b6c85db02f9c4d36a5b2287079ee2976
Autor:
Caroline Morbach, Niklas Beyersdorf, Thomas Kerkau, Gustavo Ramos, Floran Sahiti, Judith Albert, Roland Jahns, Georg Ertl, Christiane E. Angermann, Stefan Frantz, Ulrich Hofmann, Stefan Störk
Publikováno v:
ESC Heart Failure, Vol 8, Iss 4, Pp 3348-3353 (2021)
Abstract Aims It has been hypothesized that cardiac decompensation accompanying acute heart failure (AHF) episodes generates a pro‐inflammatory environment boosting an adaptive immune response against myocardial antigens, thus contributing to progr
Externí odkaz:
https://doaj.org/article/21dd7adb792648419af734c9c8f88b2d
Autor:
Nadine Gladow, Claudia Hollmann, Gustavo Ramos, Stefan Frantz, Thomas Kerkau, Niklas Beyersdorf, Ulrich Hofmann
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0227734 (2020)
Both conventional and regulatory CD4+ T-cells rely on costimulatory signals mediated by cell surface receptors including CD28 for full activation. We showed previously that stimulation of CD4+ Foxp3+ regulatory T-cells by superagonistic anti-CD28 mon
Externí odkaz:
https://doaj.org/article/8cb7e75a991a44b0ae0e22cec4647342
Autor:
Nadine Gladow, Claudia Hollmann, Gustavo Ramos, Stefan Frantz, Thomas Kerkau, Niklas Beyersdorf, Ulrich Hofmann
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235947 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0227734.].
Externí odkaz:
https://doaj.org/article/ee35b39b13a7498e94d83ec61ed979fc
Autor:
Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Thomas Kerkau, Rudolf Hagen, Stephan Hackenberg
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 11, Iss 2, Pp 133-140 (2018)
Objectives The pathophysiological mechanisms of chronic rhinosinusitis with nasal polyposis (CRSwNP) still are discussed controversially. Regulatory B cells (Breg) are responsible for the suppression of T cell activity: deficiencies for Breg have bee
Externí odkaz:
https://doaj.org/article/64a4af3df3fc43ad9626bd6f546f5b4c
Autor:
Valérie Boivin-Jahns, Kerstin Uhland, Hans-Peter Holthoff, Niklas Beyersdorf, Vladimir Kocoski, Thomas Kerkau, Götz Münch, Martin J Lohse, Martin Ungerer, Roland Jahns
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201160 (2018)
RATIONALE:Despite advances in pharmacotherapy, heart failure still incurs significant morbidity and mortality. Stimulating antibodies directed against the secondextracellular loop of the human ß1-adrenergic receptor (anti-ß1EC2) cause myocyte damag
Externí odkaz:
https://doaj.org/article/d7cea84fe6d649979c26f8103e1de8d4
Autor:
Pascal Ickrath M.D., Norbert Kleinsasser M.D., Xin Ding, Christian Ginzkey M.D., Niklas Beyersdorf M.D., Rudolf Hagen M.D., Thomas Kerkau M.D., Stephan Hackenberg M.D.
Publikováno v:
Allergy & Rhinology, Vol 8 (2017)
Background There is an ongoing discussion concerning the potential origins of chronic rhinosinusitis with nasal polyposis (CRSwNP). Objective The aim of this study was to quantify subpopulations of T cells in peripheral blood and nasal polyps in CRSw
Externí odkaz:
https://doaj.org/article/dce8936400d249a699b99a4fca696ee8
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Acute graft-versus-host disease (aGvHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell plus T cell transplantation (allo-HSCT). In this study, we investigated the requirement for CD28 co-stimulation of donor CD4+
Externí odkaz:
https://doaj.org/article/3be9a0af23fd4797a29a9d8d8bbc4a3d
Autor:
Jochen Bodem, Stefanie Bock, Anita Schuch, Rebecca Moschall, Eva-Maria Schrom, Juliane Zahn, Christian Reuter, Graeme B. Jacobs, Thomas Kerkau, Axel Rethwilm, Susan Engelbrecht, Wolfgang Preiser
Publikováno v:
Viruses, Vol 4, Iss 9, Pp 1830-1843 (2012)
The Human Immunodeficiency Virus type 1 (HIV-1) subtype C is currently the predominant subtype worldwide. Cell culture studies of Sub-Saharan African subtype C proviral plasmids are hampered by the low replication capacity of the resulting viruses, a
Externí odkaz:
https://doaj.org/article/41f482b1a67a41c7bc3508d2006556b3
Autor:
Valérie Boivin, Niklas Beyersdorf, Dieter Palm, Viacheslav O Nikolaev, Angela Schlipp, Justus Müller, Doris Schmidt, Vladimir Kocoski, Thomas Kerkau, Thomas Hünig, Georg Ertl, Martin J Lohse, Roland Jahns
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117589 (2015)
Despite recent therapeutic advances the prognosis of heart failure remains poor. Recent research suggests that heart failure is a heterogeneous syndrome and that many patients have stimulating auto-antibodies directed against the second extracellular
Externí odkaz:
https://doaj.org/article/bb5ce71e88f645a2baaa41e4f4e365b5