Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Thomas Karasic"'
Autor:
Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long, Shannon M. Pfeiffer, Jaclyn P. Lyman, Lacey J. Padrón, Deena M. Maurer, Jia Xin Yu, Christine N. Spencer, Pier Federico Gherardini, Diane M. Da Silva, Theresa M. LaVallee, Charles Abbott, Richard O. Chen, Sean M. Boyle, Neha Bhagwat, Samuele Cannas, Hersh Sagreiya, Wenrui Li, Stephanie S. Yee, Aseel Abdalla, Zhuoyang Wang, Melinda Yin, Dominique Ballinger, Paul Wissel, Jennifer Eads, Thomas Karasic, Charles Schneider, Peter O’Dwyer, Ursina Teitelbaum, Kim A. Reiss, Osama E. Rahma, George A. Fisher, Andrew H. Ko, Zev A. Wainberg, Robert A. Wolff, Eileen M. O’Reilly, Mark H. O’Hara, Christopher R. Cabanski, Robert H. Vonderheide, Erica L. Carpenter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract While high circulating tumor DNA (ctDNA) levels are associated with poor survival for multiple cancers, variant-specific differences in the association of ctDNA levels and survival have not been examined. Here we investigate KRAS ctDNA (ctKR
Externí odkaz:
https://doaj.org/article/4f9cd688d606493b979047418e6f71a0
Autor:
Rebecca Kristeleit, Howard Burris, Kristen Spencer, Sarina Piha-Paul, Hans Prenen, Tara Mitchell, David Pinato, Solmaz Sahebjam, Donna Graham, Nuria Kotecki, Eric Van Cutsem, Brant Delafontaine, Thomas Karasic, Jeannie Daniel, Kevin O’Hayer, Ryan Geschwindt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7ed5aa6600e64e098a5e3fe1502b2f72
Autor:
Kim A, Reiss, Rosemarie, Mick, Ursina, Teitelbaum, Mark, O'Hara, Charles, Schneider, Ryan, Massa, Thomas, Karasic, Rashmi, Tondon, Chioma, Onyiah, Mary Kate, Gosselin, Alyssa, Donze, Susan M, Domchek, Robert H, Vonderheide
Publikováno v:
Lancet Oncol
Establishing alternatives to lifelong chemotherapy for patients with advanced pancreatic cancer has been proposed to address chemotherapy resistance and cumulative toxicity. Poly(ADP-ribose) polymerase (PARP) inhibitors have shown efficacy in this se
Autor:
Christophe Le Tourneau, Sarina Piha-Paul, Hans Prenen, Brant Delafontaine, David Pinato, Armando Santoro, Rebecca Kristeleit, Kristen Spencer, Tara Gangadhar, Howard Burris, Nuria Kotecki, Bristi Basu, Donna Graham, Anna Maria Di Giacomo, Solmaz Sahebjam, Massimo Di Nicola, Carlos Gomez-Roca, Pascale Tomasini, Paolo Ascierto, Giuseppe Curigliano, Thomas Karasic, Ryan Geschwindt, Jeannie Daniel, Eric Van Cutsem
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Jayesh Desai, Sae-Won Han, Jong-Seok Lee, Einat Shacham-Shmueli, Erminia Massarelli, Andrés Cervantes, Elena Garralda, Alejandro Falcon, Wilson H. Miller, Eelke Gort, Thomas Karasic, Salvatore Siena, Rafal Stec, Laura Medina, Luis Paz-Arez, Angelo Delmonte, Adrian Sacher, Hans Prenen, Martin Forster, Tae Won Kim, Matthew G. Krebs, Rasha Cosman, Yoonha Choi, Sandhya Mandlekar, Mark T. Lin, Kenneth K. Yau, Julie Chang, Stephanie Royer-Joo, Neekesh V. Dharia, Jennifer L. Schutzman, Manish Patel
Publikováno v:
Cancer Research. 83:CT029-CT029
Background: GDC-6036 is an oral, highly potent and selective KRAS G12C inhibitor that demonstrated anti-tumor activity in patients with KRAS G12C-positive advanced solid tumors, including CRC. In a previously reported single-agent cohort, GDC-6036 ac
Autor:
Miguel Romanello Joaquim, Emma Furth, Yong Fan, Hee Song, Stephen Pickup, Jianbo Cao, Hoon Choi, Mamta Gupta, Quy Cao, Russell Shinohara, Deirdre McMenamin, Cynthia Clendenin, Thomas Karasic, Jeffrey Duda, James Gee, Peter O’Dwyer, Mark Rosen, Rong Zhou
Publikováno v:
Cancers; Volume 14; Issue 16; Pages: 4017
KPC (KrasG12D:Trp53R172H:Pdx1-Cre) and CKS (KrasG12D:Smad4L/L:Ptf1a-Cre) mice are genetically engineered mouse (GEM) models that capture features of human pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasms (IPMN), re