Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Thomas K. Hoang"'
Autor:
Baokun He, Yuying Liu, Thomas K. Hoang, Xiangjun Tian, Christopher M. Taylor, Meng Luo, Dat Q. Tran, Nina Tatevian, J. Marc Rhoads
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Regulatory T cell (Treg) deficiency leads to IPEX syndrome, a lethal autoimmune disease, in Human and mice. Dysbiosis of the gut microbiota in Treg-deficient scurfy (SF) mice has been described, but to date, the role of the gut mi
Externí odkaz:
https://doaj.org/article/0adfc440e27441b198c943134a3ca0ec
Autor:
Baokun He, Thomas K. Hoang, Xiangjun Tian, Christopher M. Taylor, Eugene Blanchard, Meng Luo, Meenakshi B. Bhattacharjee, Jasmin Freeborn, Sinyoung Park, Jacob Couturier, John William Lindsey, Dat Q. Tran, Jon Marc Rhoads, Yuying Liu
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The gut microbiome plays an important role in immune function and has been implicated in multiple sclerosis (MS). However, how and if the modulation of microbiota can prevent or treat MS remain largely unknown. In this study, we showed that probiotic
Externí odkaz:
https://doaj.org/article/2c32ce2672ea419e95fd970a91c54513
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The lack of a functional Foxp3 transcription factor and regulatory T (Treg) cells causes lethal, CD4+ T cell-driven autoimmune diseases in scurfy (SF) mice and humans. Recent studies have shown that adenosine A2A receptor activation limits inflammati
Externí odkaz:
https://doaj.org/article/8b4589a4c0ac4dda8a429b15aada7335
Autor:
Meng Luo, Stefan Roos, Jasmin Freeborn, Christopher M. Taylor, J. Marc Rhoads, Thomas K. Hoang, Evelyn S. Park, Yuying Liu
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Treg deficiency causes a lethal, CD4(+) T cell-driven autoimmune disease called IPEX syndrome (immunodysregulation, polyendocrinopathy, and enteropathy, with X-linked inheritance) in humans and in the scurfy (SF) mouse, a mouse model of the disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c7b27975e9b22d21f24a3ce836f41b
https://europepmc.org/articles/PMC8285589/
https://europepmc.org/articles/PMC8285589/
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 315:G231-G240
Lactobacillus reuteri DSM 17938 (LR 17938) has been shown to reduce the incidence and severity of necrotizing enterocolitis (NEC). It is unclear if preventing NEC by LR 17938 is mediated by Toll-like receptor 2 (TLR2), which is known to mediate proin
Autor:
Thomas K, Hoang, Jasmin, Freeborn, Ting, Wang, Tu, Mai, Baokun, He, Sinyoung, Park, Dat Q, Tran, Stefan, Roos, J Marc, Rhoads, Yuying, Liu
Publikováno v:
Journal of probiotics & health
Background and objective: Breast milk has many growth-promoting and immune-active components, including transforming growth factor-β, lactoferrin, lysozyme, immunoglobulin A, and prebiotics such as the human milk oligosaccharides. Treatment with Lac
Autor:
Yuying Liu, Jasmin Freeborn, J. Marc Rhoads, Christopher M. Taylor, Thomas K. Hoang, Evelyn S. Park, Stefan Roos, Meng Luo
Publikováno v:
Gastroenterology. 160:S-730
Autor:
Meng Luo, Christopher M. Taylor, Michael R. Blackburn, Nina Tatevian, Michael J. Ferris, Yuying Liu, Baokun He, Ting Wang, Stefan Roos, Thomas Gomez, J. Marc Rhoads, Dat Q. Tran, Jose G. Molina, Fayong Luo, Jain Zhou, Xiangjun Tian, Thomas K. Hoang
Publikováno v:
The Journal of Experimental Medicine
He et al. show that T reg deficiency markedly induces autoimmunity and shifts gut microbiota. Remodeling microbiota by Lactobacillus reuteri was found to inhibit autoimmunity via the metabolite inosine, which interacts with the adenosine A2A receptor
Autor:
Thomas K. Hoang, Dat Q. Tran, J. Marc Rhoads, Jacob Couturier, Sinyoung Park, Guoyao Wu, Meng Luo, Eugene Blanchard, Baokun He, Christopher M. Taylor, Jasmin Freeborn, Yuying Liu, Xiangjun Tian, Stefan Roos
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Early administration of Lactobacillus reuteri DSM 17938 (LR) prevents necrotizing enterocolitis and inhibits regulatory T-cell (Treg)-deficiency-associated autoimmunity in mice. In humans, LR reduces crying time in breastfed infants with colic, modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258c69db387d2ae6e7eb82d6e8049b8b
https://europepmc.org/articles/PMC6962498/
https://europepmc.org/articles/PMC6962498/
Autor:
Dat Q. Tran, Christopher M. Taylor, Yuying Liu, Xiangjun Tian, Thomas K. Hoang, Nina Tatevian, Meng Luo, Baokun He, J. Marc Rhoads
Publikováno v:
Microbiome
Microbiome, Vol 7, Iss 1, Pp 1-12 (2019)
Microbiome, Vol 7, Iss 1, Pp 1-12 (2019)
Background Regulatory T cell (Treg) deficiency leads to IPEX syndrome, a lethal autoimmune disease, in Human and mice. Dysbiosis of the gut microbiota in Treg-deficient scurfy (SF) mice has been described, but to date, the role of the gut microbiota