Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study.

Autor: Manuel P Pereira, Mads U Werner, Thomas K Ringsted, Michael C Rowbotham, Bradley K Taylor, Joergen B Dahl

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64608 (2013)

Development of secondary hyperalgesia following a cutaneous injury is a centrally mediated, robust phenomenon. The pathophysiological role of endogenous opioid signalling to the development of hyperalgesia is unclear. Recent animal studies, carried o

Externí odkaz: https://doaj.org/article/d620722f090b4bac9f13202ac598527b

A national center for persistent severe pain after groin hernia repair: Five-year prospective data

Autor: Thomas K. Ringsted, Jacob Rosenberg, Joakim M. Bischoff, Henrik Kehlet, Morten Aagaard Petersen, Mads U. Werner, E. Jensen

Publikováno v: Medicine
Jensen, E K, Ringsted, T K, Bischoff, J M, Petersen, M A, Rosenberg, J, Kehlet, H & Werner, M U 2019, ' A national center for persistent severe pain after groin hernia repair : Five-year prospective data ', Medicine (Baltimore), vol. 98, no. 33, pp. e16600 . https://doi.org/10.1097/MD.0000000000016600

Supplemental Digital Content is available in the text
Severe persistent pain after groin hernia repair impairs quality-of-life. Prospective, consecutive cohort study including patients with pain-related impairment of physical and social life. Re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c198675fb15299c14fe8aa83738f0b76
https://pubmed.ncbi.nlm.nih.gov/31415351

Quantitative Sensory Testing in Patients With Postthoracotomy Pain Syndrome

Autor: Thomas K. Ringsted, Kim Wildgaard, Mads U. Werner, Henrik Kehlet

Publikováno v: The Clinical Journal of Pain. 29:784-790

OBJECTIVES: Quantitative sensory testing is a reference method for characterization of postsurgical neuropathic components. Correct interpretation of data requires detailed information concerning the validity of the testing methods. The objective of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36604751e4eeecc778569a7d7f4667aa
https://doi.org/10.1097/ajp.0b013e318277b6ea

The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided tender point blockade

Autor: Mads U. Werner, Henrik Kehlet, Nelun Wijayasinghe, Joakim M. Bischoff, Thomas K. Ringsted

Publikováno v: British journal of anaesthesia. 116(6)

Background Severe, persistent inguinal postherniorrhaphy pain (PIPP) is a debilitating condition that develops in 2–5% of patients. PIPP may be neuropathic in nature, yet the lesion in the peripheral nervous system has not been located. Most PIPP-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7d31dc99fd96c2081e4af0b3e6deda
https://pubmed.ncbi.nlm.nih.gov/27199314

Persistent postsurgical pain after video-assisted thoracic surgery--an observational study

Autor: Henrik Jessen Hansen, Henrik Kehlet, Kim Wildgaard, Thomas K. Ringsted, René Horsleben Petersen

Publikováno v: Acta anaesthesiologica Scandinavica. 60(5)

Background The risk of persistent postsurgical pain (PPP) and subsequent pain-related functional impairment may potentially be reduced by video-assisted thoracic surgery (VATS) compared to thoracotomy. The aim of the study was therefore to assess in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab43a026bbbe9a5967ac85012d05ea28
https://pubmed.ncbi.nlm.nih.gov/26792257