Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas K, Smylla"'
Publikováno v:
Traffic. 23:42-62
Plasma membrane protein trafficking is of fundamental importance for cell function and cell integrity of neurons and includes regulated protein recycling. In this work, we report a novel role of the endoplasmic reticulum (ER) for protein recycling as
Publikováno v:
International journal of molecular sciences. 23(23)
Vertebrate and fly rhodopsins are prototypical GPCRs that have served for a long time as model systems for understanding GPCR signaling. Although all rhodopsins seem to become phosphorylated at their C-terminal region following activation by light, t
Publikováno v:
Journal of visualized experiments : JoVE. (179)
Membrane protein trafficking regulates the incorporation and removal of receptors and ion channels into the plasma membrane. This process is fundamentally important for cell function and cell integrity of neurons. Drosophila photoreceptor cells have
Publikováno v:
Journal of Visualized Experiments.
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8930, p 8930 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 8930, p 8930 (2021)
The Drosophila eye has been used extensively to study numerous aspects of biological systems, for example, spatio-temporal regulation of differentiation, visual signal transduction, protein trafficking and neurodegeneration. Right from the advent of
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140007 (2015)
Hairless (H) is the major antagonist within the Notch signalling pathway of Drosophila melanogaster. By binding to Suppressor of Hairless [Su(H)] and two co-repressors, H induces silencing of Notch target genes in the absence of Notch signals. We hav
Externí odkaz:
https://doaj.org/article/4bb6e7e5eff941b594b812e8f2da3379
Publikováno v:
Journal of Histochemistry & Cytochemistry. 67:745-757
Drosophila photoreceptor cells are employed as a model system for studying membrane protein transport. Phototransduction proteins like rhodopsin and the light-activated TRPL ion channel are transported within the photoreceptor cell, and they change t
Publikováno v:
Development Genes and Evolution. 229:13-24
During development of higher animals, the Notch signalling pathway governs cell type specification by mediating appropriate gene expression responses. In the absence of signalling, Notch target genes are silenced by repressor complexes. In the model
Publikováno v:
Journal of Histochemistry and Cytochemistry
Drosophila photoreceptor cells are employed as a model system for studying membrane protein transport. Phototransduction proteins like rhodopsin and the light-activated TRPL ion channel are transported within the photoreceptor cell, and they change t
Autor:
Anette Preiss, Ludmilla Kober, Dieter Maier, Tilman Borggrefe, Mirjam Zimmermann, Thomas K. Smylla, Philipp Hoffmeister, Jan Reichmuth, Anja C. Nagel, Dorina B. Wolf, Franz Oswald, Aleksandra Turkiewicz
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1866(10)
Activation and repression of Notch target genes is mediated by transcription factor CSL, known as Suppressor of Hairless (Su(H)) in Drosophila and CBF1 or RBPJ in human. CSL associates either with co-activator Notch or with co-repressors such as Dros