Zobrazeno 1 - 10
of 429
pro vyhledávání: '"Thomas K, Hoffmann"'
Autor:
Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles they are involved in
Externí odkaz:
https://doaj.org/article/8febd94011434cd39ad0e08df9476fce
Autor:
Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influenc
Externí odkaz:
https://doaj.org/article/00d90afcd16e4cecbcf18e983b6db96a
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractBackground Hereditary angioedema with normal C1-inhibitor (HAE-nC1-INH) is a rare genetic disease. The symptoms can resemble other forms of hereditary angioedema (HAE), but the specific laboratory values are inconspicuous. The knowledge about
Externí odkaz:
https://doaj.org/article/752857e1055a48539a0ceb361b231f64
Autor:
Tsima Abou Kors, Matthias Meier, Lena Mühlenbruch, Annika C. Betzler, Franziska Oliveri, Martin Bens, Jaya Thomas, Johann M. Kraus, Johannes Doescher, Adrian von Witzleben, Linda Hofmann, Jasmin Ezic, Diana Huber, Julian Benckendorff, Thomas F. E. Barth, Jens Greve, Patrick J. Schuler, Cornelia Brunner, Jonathan M. Blackburn, Thomas K. Hoffmann, Christian Ottensmeier, Hans A. Kestler, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis antigens (CTA)
Externí odkaz:
https://doaj.org/article/395296b0c62b42a7af04bb14da175331
Autor:
Julius M. Vahl, Gabriele Nagel, Tsima Abou Kors, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Ayla Grages, Marie N. Theodoraki, Jens Greve, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Stephan Stilgenbauer, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 23, Pp 21426-21435 (2023)
Abstract Introduction Demographics are important prognostic factors in malignant diseases. A nationwide analysis concerning the prognostic impact of demographics in head and neck cancer (HNC) patients (HNCP) has not been performed previously. Methods
Externí odkaz:
https://doaj.org/article/403267fe0932404bb41475658f084ee6
Autor:
Julius M. Vahl, Gabriele Nagel, Ayla Grages, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Marie‐Nicole Theodoraki, Jens Greve, Tsima Aboukors, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18826-18836 (2023)
Abstract Background Demographic development in rural and urban areas differs substantially. Demographics and access to specialized head and neck cancer centers may affect head and neck cancer patients' (HNCP) outcomes. Here, we compare epidemiologica
Externí odkaz:
https://doaj.org/article/a1465fdd240b4ed1b704c84412fc0dbc
Autor:
Lisa T. Huber, Johann M. Kraus, Jasmin Ezić, Amin Wanli, Marco Groth, Simon Laban, Thomas K. Hoffmann, Barbara Wollenberg, Hans A. Kestler, Cornelia Brunner
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 422-446 (2023)
Aim: Recently, a tumor cell-platelet interaction was identified in different tumor entities, resulting in a transfer of tumor-derived RNA into platelets, named further “tumor-educated platelets (TEP)”. The present pilot study aims to investigate
Externí odkaz:
https://doaj.org/article/7f08bddc60874ffa92d65bc1ddf7441a
Autor:
Linus L. Kienle, Leon R. Schild, Felix Böhm, Rene Grässlin, Jens Greve, Thomas K. Hoffmann, Patrick J. Schuler
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
BackgroundFor the surgical treatment of early-stage laryngeal cancer, the use of transoral laser microsurgery (TLM) has emerged as the gold standard. However, this procedure requires a straight line of sight to the operating field. Therefore, the pat
Externí odkaz:
https://doaj.org/article/db8d4479e91043b08ea257b090b9f7a3
Autor:
Christoph Leinert, Marina Fotteler, Thomas Derya Kocar, Dhayana Dallmeier, Hans A Kestler, Dennis Wolf, Florian Gebhard, Adriane Uihlein, Florian Steger, Reinhold Kilian, Annabel S Mueller-Stierlin, Christoph W Michalski, André Mihaljevic, Christian Bolenz, Friedemann Zengerling, Elena Leinert, Sabine Schütze, Thomas K Hoffmann, Graziano Onder, Karen Andersen-Ranberg, Desmond O'Neill, Martin Wehling, Johannes Schobel, Walter Swoboda, Michael Denkinger, SURGE-Ahead Study Group
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287230 (2023)
IntroductionGeriatric co-management is known to improve treatment of older adults in various clinical settings, however, widespread application of the concept is limited due to restricted resources. Digitalization may offer options to overcome these
Externí odkaz:
https://doaj.org/article/83f08ee3808844ff82c53eb529e49a53
Autor:
Linda Hofmann, Marie Waizenegger, Ralph Röth, Stefanie Schmitteckert, Daphne Engelhardt, Patrick J. Schuler, Simon Laban, Thomas K. Hoffmann, Cornelia Brunner, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundEpithelial to mesenchymal transition (EMT) is a key process in carcinogenesis of head and neck squamous cell carcinoma (HNSCC), contributing to tumor invasiveness, distant metastasis, and recurrence. Exosomes are known mediators and regulat
Externí odkaz:
https://doaj.org/article/da495342c7434169a99bd62712d7b29c