Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas J. Younts"'
Autor:
Matthew E. Klein, Thomas J. Younts, Carmen Freire Cobo, Adina R. Buxbaum, Jonathan Aow, Hediye Erdjument-Bromage, Stéphane Richard, Roberto Malinow, Thomas A. Neubert, Robert H. Singer, Pablo E. Castillo, Bryen A. Jordan
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1789-1799.e6 (2019)
Summary: The transport and translation of dendritic mRNAs by RNA-binding proteins (RBPs) allows for spatially restricted gene expression in neuronal processes. Although local translation in neuronal dendrites is now well documented, there is little e
Externí odkaz:
https://doaj.org/article/232f6d1042a2448db13d6265a23fcfc1
Autor:
Brian W Jones, Jennifer Deem, Thomas J Younts, Michael Weisenhaus, Christina A Sanford, Margaret C Slack, Jenesa Chin, Daniela Nachmanson, Alex McKennon, Pablo E Castillo, G Stanley McKnight
Publikováno v:
eLife, Vol 5 (2016)
Protein Kinase A (PKA) mediates synaptic plasticity and is widely implicated in learning and memory. The hippocampal dentate gyrus (DG) is thought to be responsible for processing and encoding distinct contextual associations in response to highly si
Externí odkaz:
https://doaj.org/article/ccb6d67e37424b3596d95ff7b4e0d75b
Autor:
Paul Anthony Kirkby, Theo Koimtzis, Antoine M. Valera, R. Angus Silver, George Konstantinou, Geoffrey J. Evans, Chiara Baragli, Hana Roš, Sameer A Punde, Isaac H. Bianco, Joanna Yn Lau, Boris Marin, K. M. Naga Srinivas Nadella, Diccon Coyle, Thomas J. Younts, Victoria A. Griffiths
Publikováno v:
Nature methods
Two-photon microscopy is widely used to investigate brain function across multiple spatial scales. However, measurements of neural activity are compromised by brain movement in behaving animals. Brain motion-induced artefacts are typically corrected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26214f78f2c5e1ed2c41a9f3b7e6db1
https://doi.org/10.1038/s41592-020-0851-7
https://doi.org/10.1038/s41592-020-0851-7
Publikováno v:
Annual Review of Neuroscience. 41:299-322
Long-lasting changes of brain function in response to experience rely on diverse forms of activity-dependent synaptic plasticity. Chief among them are long-term potentiation and long-term depression of neurotransmitter release, which are widely expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a260d262aa8f286dce8ffe8f222d92
https://doi.org/10.1146/annurev-neuro-080317-062155
https://doi.org/10.1146/annurev-neuro-080317-062155
Autor:
Barna Dudok, Hannah R. Monday, Pablo E. Castillo, István Katona, Matthew E. Klein, Bryen A. Jordan, Thomas J. Younts
Publikováno v:
Neuron. 92:479-492
Long-term changes of neurotransmitter release are critical for proper brain function. However, the molecular mechanisms underlying these changes are poorly understood. While protein synthesis is crucial for the consolidation of postsynaptic plasticit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc9950fb0e2752e62c0faa8176a900a
https://doi.org/10.1016/j.neuron.2016.09.040
https://doi.org/10.1016/j.neuron.2016.09.040
Autor:
Thomas J. Younts, Pablo E. Castillo
Publikováno v:
Current Opinion in Neurobiology. 26:42-50
Significant progress has been made in our understanding of how endogenous cannabinoids (eCBs) signal at excitatory and inhibitory synapses in the central nervous system (CNS). This review discusses how eCBs regulate inhibitory interneurons, their syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2855cf35a1e9d86b89ef48660ba578f0
https://doi.org/10.1016/j.conb.2013.12.006
https://doi.org/10.1016/j.conb.2013.12.006
Autor:
Shiho Kobayashi, Anjail A. Ameen, Andrea N. Giordano, Thomas J. Younts, Michael W. Forney, Shawn G. Ridlen, Jeffrey R. Alston, Sarah S. Subaran, Jordan C. Poler, Natalie P. Herring
Publikováno v:
Phys. Chem. Chem. Phys.. 16:5855-5865
The rational design of supraparticle assemblies requires a detailed understanding of directed assembly processes. The stability of dispersions of nanoscale materials, like single-walled carbon nanotubes (SWCNTs), is still not fully understood, nor ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485236899ca362c916f264edbd05b3ca
https://doi.org/10.1039/c3cp55530e
https://doi.org/10.1039/c3cp55530e
Autor:
Thomas A. Neubert, Carmen Freire Cobo, Jonathan Aow, Bryen A. Jordan, Thomas J. Younts, Hediye Erdjument-Bromage, Adina R. Buxbaum, Pablo E. Castillo, Matthew E. Klein, Stéphane Richard, Robert H. Singer, Roberto Malinow
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 7, Pp 1789-1799.e6 (2019)
Cell Reports, Vol 29, Iss 7, Pp 1789-1799.e6 (2019)
SUMMARY The transport and translation of dendritic mRNAs by RNA-binding proteins (RBPs) allows for spatially restricted gene expression in neuronal processes. Although local translation in neuronal dendrites is now well documented, there is little ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040593d1581cd5e7b7f788093ae9215f
https://doi.org/10.1016/j.celrep.2019.10.030
https://doi.org/10.1016/j.celrep.2019.10.030
Publikováno v:
Proceedings of the National Academy of Sciences. 110:3125-3130
Proper synaptic function requires the spatial and temporal compartmentalization of RNA metabolism via transacting RNA-binding proteins (RBPs). Loss of RBP activity leads to abnormal posttranscriptional regulation and results in diverse neurological d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5127f87bf8c175d19ed563440f16eca
https://doi.org/10.1073/pnas.1209811110
https://doi.org/10.1073/pnas.1209811110
Autor:
Brian W. Jones, Jenesa Chin, Christina A Sanford, Thomas J. Younts, Pablo E. Castillo, Margaret C Slack, Alex McKennon, Daniela Nachmanson, G. Stanley McKnight, Michael Weisenhaus, Jennifer D. Deem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ccd0d8168121101884fe6b87caa6daf
https://doi.org/10.7554/elife.20695.015
https://doi.org/10.7554/elife.20695.015
