Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Thomas J. Widmann"'
Autor:
Manvendra Singh, Aleksandra M. Kondrashkina, Thomas J. Widmann, Jose L. Cortes, Vikas Bansal, Jichang Wang, Christine Römer, Marta Garcia-Canadas, Jose L. Garcia-Perez, Laurence D. Hurst, Zsuzsanna Izsvák
Publikováno v:
PLoS Biology, Vol 21, Iss 6 (2023)
There remains much that we do not understand about the earliest stages of human development. On a gross level, there is evidence for apoptosis, but the nature of the affected cell types is unknown. Perhaps most importantly, the inner cell mass (ICM),
Externí odkaz:
https://doaj.org/article/c79ae257f97a464eb8488ff58e3fdc6f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Adhesion to the extracellular matrix (ECM) is required for normal epithelial cell survival. Disruption of this interaction leads to a specific type of apoptosis known as anoikis. Yet, there are physiological and pathological situations in which cells
Externí odkaz:
https://doaj.org/article/df1e0f690b8049c2921b8115c51ff9a5
Autor:
Javier Valverde-Pozo, Jose Manuel Paredes, Maria Eugenia García-Rubiño, Thomas J. Widmann, Carmen Griñan-Lison, Silvia Lobon-Moles, Juan Antonio Marchal, Jose Maria Alvarez-Pez, Eva Maria Talavera
Publikováno v:
Chemosensors, Vol 11, Iss 2, p 145 (2023)
Melanoma is a type of highly malignant and metastatic skin cancer. In situ molecular imaging of endogenous levels of the melanoma biomarker tyrosinase (TYR) may decrease the likelihood of mortality. In this study, we proposed the weakly fluorescent p
Externí odkaz:
https://doaj.org/article/2eabe1cab7c3440dae96467ea361e8b1
Autor:
Javier Valverde-Pozo, Jose M. Paredes, Thomas J. Widmann, Carmen Griñan-Lison, Giada Ceccarelli, Antimo Gioiello, M. Eugenia Garcia-Rubiño, Juan A. Marchal, Jose M. Alvarez-Pez, Eva M. Talavera
Publikováno v:
ACS Sensors. 8:1064-1075
DPP IV, otherwise known as CD26 lymphocyte T surface antigen, is a transmembrane glycoprotein also found in circulation in the blood. It plays an important role in several processes like glucose metabolism and T-cell stimulation. Moreover, it is over
Autor:
Jose L. Garcia-Perez, Philip Ng, Alejandro Rubio, Laura Sánchez, Javier García-Castro, Sara R. Heras, John L. Goodier, Angela Macia, Eva Blanco-Jimenez, Martin Muñoz-Lopez, Alysson R. Muotri, Meriem Benkaddour-Boumzaouad, Thomas J. Widmann, Verónica Ayllón, Suyapa Amador-Cubero, Pablo Menendez
Publikováno v:
Genome research, vol 27, iss 3
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Genome Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Macia, A, Widmann, T J, Heras, S R, Ayllon, V, Sanchez, L, Benkaddour-Boumzaouad, M, Muñoz-Lopez, M, Rubio, A, Amador-Cubero, S, Blanco-Jimenez, E, Garcia-Castro, J, Menendez, P, Ng, P, Muotri, A R, Goodier, J L & Garcia-Perez, J L 2017, ' Engineered LINE-1 retrotransposition in nondividing human neurons ', Genome Research, vol. 27, no. 3, pp. 335-348 . https://doi.org/10.1101/gr.206805.116
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Genome Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Macia, A, Widmann, T J, Heras, S R, Ayllon, V, Sanchez, L, Benkaddour-Boumzaouad, M, Muñoz-Lopez, M, Rubio, A, Amador-Cubero, S, Blanco-Jimenez, E, Garcia-Castro, J, Menendez, P, Ng, P, Muotri, A R, Goodier, J L & Garcia-Perez, J L 2017, ' Engineered LINE-1 retrotransposition in nondividing human neurons ', Genome Research, vol. 27, no. 3, pp. 335-348 . https://doi.org/10.1101/gr.206805.116
Half the human genome is made of transposable elements (TEs), whose ongoing activity continues to impact our genome. LINE-1 (or L1) is an autonomous non-LTR retrotransposon in the human genome, comprising 17% of its genomic mass and containing an ave
Publikováno v:
Garcia-Perez, J L, Widmann, T J & Adams, I R 2016, ' The impact of transposable elements on mammalian development ', Development, vol. 143, no. 22, pp. 4101-4114 . https://doi.org/10.1242/dev.132639
Despite often being classified as selfish or junk DNA, transposable elements (TEs) are a group of abundant genetic sequences that have a significant impact on mammalian development and genome regulation. In recent years, our understanding of how pre-
Autor:
Gerald G. Schumann, Thomas J. Widmann, Marta García-Cañadas, Laurence D. Hurst, Vikas Bansal, Manvendra K. Singh, Zsuzsanna Izsvák, Stephanie Wunderlich, Jose L. Garcia-Perez, José Luis Cortés, Ulrich Martin
Is the human early embryo unique in lacking an inner cell-mass (ICM) and having parallel development? We reanalyse single-cell transcriptomic data and stain human embryos in situ to reveal both classical step-wise development and a transcriptomically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40b798ec748d561a775e13e485854ab
https://doi.org/10.1101/318329
https://doi.org/10.1101/318329
Autor:
Thomas J. Widmann, Christian Dahmann
Publikováno v:
Developmental Biology. 334(1):161-173
The control of cell morphology is important for shaping animals during development. Here we address the role of the Wnt/Wingless signal transduction pathway and two of its target genes, vestigial and shotgun (encoding E-cadherin), in controlling the
Publikováno v:
Visualization and Data Analysis
Quantifying and visualizing the shape of developing biological tissues provide information about the morphogenetic processes in multicellular organisms. The size and shape of biological tissues depend on the number, size, shape, and arrangement of th
Publikováno v:
BioVis
Quantifying and visualizing the shape of developing biological tissues provide information about the morphogenetic processes in multicellular organisms. The size and shape of biological tissues depend on the number, size, shape, and arrangement of th