Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thomas J. Onofrey"'
Autor:
Thomas J. Onofrey, Bruce Wallace, Neema Jamshidi, Ron Sosnowski, C. Gurtner, Carl F. Edman, Robert W. Haigis, Eugene Tu, Michael J. Heller
Publikováno v:
ELECTROPHORESIS. 23:1543-1550
A variety of electronic DNA array devices and techniques have been developed that allow electric field enhanced hybridization to be carried out under special low-conductance conditions. These devices include both planar microelectronic DNA array/chip
Autor:
Peide Gu, Thomas A. Spencer, Alfredo Castro, Ishaiahu Shechter, Reginald O. Cann, Thomas J. Onofrey, Guojian Jiang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2585-2588
Zwitterions such as farnesyl sulfobetaine 8 are a new type of inhibitor of squalene synthase that, while maintaining overall neutrality, mimic both the carbocationic and anionic moieties of presumed reaction intermediates. The most effective zwitteri
Publikováno v:
Analytica Chimica Acta. 228:235-240
It is shown that trichloro-1,3,5-triazine can be attached to aminated silica gel at two sites. This method of activating the silica gel for immobilization of analytical reagents is considered in relation to the typical single-site method of attachmen
Autor:
Christian, Gurtner, Eugene, Tu, Neema, Jamshidi, Robert W, Haigis, Thomas J, Onofrey, Carl F, Edman, Ron, Sosnowski, Bruce, Wallace, Michael J, Heller
Publikováno v:
Electrophoresis. 23(10)
A variety of electronic DNA array devices and techniques have been developed that allow electric field enhanced hybridization to be carried out under special low-conductance conditions. These devices include both planar microelectronic DNA array/chip
Autor:
Thomas J. Onofrey, Thomas A. Spencer, Ishaiahu Shechter, Reginald O. Cann, Guojian Jiang, Alfredo Castro, Jonathon S. Russel, Peide Gu, Daniel E. Blanchard, Laura E. Lee
Publikováno v:
The Journal of organic chemistry. 64(3)
A substantial number of sulfobetaines (e.g., 10) have been synthesized and evaluated as inhibitors of squalene synthase (SS) on the basis of the idea that their zwitterionic structure would have properties conducive both to binding in the active site
Publikováno v:
The Journal of Organic Chemistry. 62:5658-5659