Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Thomas J. McConnell"'
Autor:
Evgueni I. Kountikov, Eva Bengtén, Ulla B. Godwin, Mohadetheh Moulana, Tor B. Stuge, Thomas J. McConnell, Norman W. Miller, Melanie Wilson, Mark Albertino, Jason P. Evenhuis
Publikováno v:
Veterinary Immunology and Immunopathology. 126:120-130
This study characterizes four monoclonal antibodies (mAb) developed against the major histocompatibility complex (MHC) class II beta chain of the channel catfish, Ictalurus punctatus. Immunoprecipitations using catfish clonal B cells revealed that ea
Autor:
Brandon J. Cuthbertson, Steven Kazianis, Michael J. Ryan, Jack da Silva, Thomas J. McConnell, Kyle Summers, Gerald A. Capraro, Gil G. Rosenthal, Kelly E. Roney
Publikováno v:
Genetica. 135:379-390
Two MHC class II loci, DAB (a classical class II locus) and DXB (putatively a non-classical class II locus), were sequenced in samples of individuals from two populations of swordtail fish, Xiphophorus multilineatus and X. pygmaeus. The DAB locus sho
Publikováno v:
Developmental & Comparative Immunology. 30:772-782
The glycans associated with mammalian major histocompatibility complex (MHC) class II molecules have been studied extensively. Co-translational and post-translational addition of sugar molecules to proteins confers many structural and modulatory func
Publikováno v:
Journal of Immunological Methods. 297:53-60
Near-infrared Raman spectroscopy may provide a highly sensitive, noninvasive means to identify activation status of leukocytes. The purpose of the current study was to establish Raman spectroscopic characteristics of T cell activation. Activation of
Autor:
James R. Fuller, Mark Albertino, Benjamin D Machon, Ulla B. Godwin, Joshua E. Pitzer, Thomas J. McConnell, Kelly P. Kearse
Publikováno v:
Developmental & Comparative Immunology. 28:603-617
Folding and assembly of MHC molecules in mammals occurs in the endoplasmic reticulum (ER), but has not been studied in teleosts. Calnexin (CNX) is an ER chaperone that associates with glycoproteins bearing a monoglucosylated N-linked oligosaccharide
Publikováno v:
Allergy. 58:342-349
Individuals sensitized to fire ant stings show immunoglobulin (Ig)E antibodies against the venom protein Sol i 3. We determined the full-length complementary DNA (cDNA) sequence of this protein and expressed recombinant Sol i 3 in immunogenic form. T
Publikováno v:
Immunology & Cell Biology. 81:8-19
This study compared myelin basic protein-specific T cells from Lewis rats that were derived in the presence of either rat IL-4 or IL-2. Interleukin-4 was a maintenance factor that enabled derivation of long-term T cell lines. When activated, IL-4 dep
Publikováno v:
Cellular Immunology. 211:51-60
IL-2 is a principal autocrine growth factor that promotes T-cell activation and proliferation. However, IL-2 has also been implicated as a key intermediate in the induction and maintenance of self-tolerance in vivo. The purpose of this study was to a
Autor:
Melanie Wilson, Antao A, Norman W. Miller, L.W. Clem, Thomas J. McConnell, Ulla B. Godwin, V.G. Chinchar
Publikováno v:
Developmental & Comparative Immunology. 24:609-622
In order to characterize the Major histocompatibility complex (MHC) class II A genes of the channel catfish (Ictalurus punctatus) a cDNA library was screened and PCR was performed. Four different full-length cDNA sequences for MHC class II A genes we
Publikováno v:
Immunogenetics. 49:303-311
Four cDNAs encoding the major histocompatibility complex (MHC) class I alpha chain were isolated from a channel catfish clonal B-cell cDNA library. Sequence analysis suggests these cDNAs represent three different MHC class I loci. All cDNAs encoded c