Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Thomas J. Magliery"'
Autor:
Mohosin Sarkar, Christina Keventzidis Harsch, George T. Matic, Kathryn Hoffman, Joseph R. Norris, Tamara C. Otto, David E. Lenz, Douglas M. Cerasoli, Thomas J. Magliery
Publikováno v:
Journal of Lipids, Vol 2012 (2012)
Paraoxonase-1 (PON1) is a serum protein, the activity of which is related to susceptibility to cardiovascular disease and intoxication by organophosphorus (OP) compounds. It may also be involved in innate immunity, and it is a possible lead molecule
Externí odkaz:
https://doaj.org/article/35be391fb4584692816b53e50b774e5a
Autor:
Portia L. Thomas, Mikhail M. Dikov, Longzhu Piao, Parvathi Ranganathan, Anneliese Antonucci, Maria Teresa P. de Aquino, David P. Carbone, Anwari Akhter, Roman V. Uzhachenko, Michael J. Koenig, Rajeswara Rao Arasada, I S Chekneva, Jason V. Evans, Nicholas E. Long, Pierre P. Massion, Thomas J. Magliery, Anna Valujskikh, Elena E. Tchekneva, Mounika U.L. Goruganthu, Anil Shanker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Notch intercellular communication instructs tissue-specific T-cell development and function. In this study, we explored the roles of dendritic cell (DC)-expressed Notch ligands in the regulation of T-cell effector function. Methods We gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18336c6dc13c8f2708b1f3a817ece8cb
http://link.springer.com/article/10.1186/s40425-019-0566-4
http://link.springer.com/article/10.1186/s40425-019-0566-4
Autor:
Laura Caleca, Anna Laura Putignano, Mara Colombo, Caterina Congregati, Mohosin Sarkar, Thomas J Magliery, Carla B Ripamonti, Claudia Foglia, Bernard Peissel, Daniela Zaffaroni, Siranoush Manoukian, Carlo Tondini, Monica Barile, Valeria Pensotti, Loris Bernard, Laura Papi, Paolo Radice
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86924 (2014)
The identification of founder mutations in cancer predisposing genes is important to improve risk assessment in geographically defined populations, since it may provide specific targets resulting in cost-effective genetic testing. Here, we report the
Externí odkaz:
https://doaj.org/article/562f557d16f34e7c8f17be5084a485ae
Autor:
Thomas J. Magliery, Tijana Z. Grove
Publikováno v:
Current Opinion in Structural Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1dd483f2f564ddc7b2020adadf1698b
https://pubmed.ncbi.nlm.nih.gov/32690369
https://pubmed.ncbi.nlm.nih.gov/32690369
Autor:
Kimberly Stephany, David Bowles, Thomas J. Magliery, Jason J. Lavinder, Chunhua Yuan, Alexandar L. Hansen
Publikováno v:
Biomolecular NMR Assignments. 12:345-350
Repressor of primer (Rop, or ROM, RNA I modulator) is a 63 amino acid four-helix bundle protein that exists in solution as an anti-parallel homodimer. This protein has been extensively studied, including by X-ray crystallography, NMR, rational design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbeb8b60c3ee65138f23ec31f4adb98
https://doi.org/10.1007/s12104-018-9837-0
https://doi.org/10.1007/s12104-018-9837-0
Autor:
Chunhua Yuan, David Bowles, Calvin A. Rhoads, Thomas J. Magliery, Sidharth Mohan, Alexandar L. Hansen
Publikováno v:
Biomolecular NMR Assignments. 12:291-295
Er-23 is a small, 51 amino acid, disulfide-rich pheromone protein used for cell signaling by Euplotes raikovi. Ten of the 51 amino acids are cysteine, allowing up to five disulfide bonds. Previous NMR work with Er-23 utilized homologously expressed p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858e5370ec5ff67e72f0ff5dd2af95a6
https://doi.org/10.1007/s12104-018-9825-4
https://doi.org/10.1007/s12104-018-9825-4
Autor:
Edward W. Martin, Nicholas E. Long, Michael F. Tweedle, Thomas J. Magliery, Brandon J. Sullivan, Haiming Ding, Li Gong
Publikováno v:
Molecular Imaging and Biology. 20:47-54
Optical surgical navigation (OSN) will be a potent tool to help surgeons more accurately and efficiently remove tumors. The purpose of this study was to evaluate a novel humanized 3E8 antibody (3E8 MAb) fragment site-specifically conjugated with IR80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f72f8d1d92c026bf6c0c6992d1ca64
https://doi.org/10.1007/s11307-017-1096-4
https://doi.org/10.1007/s11307-017-1096-4
Autor:
Ernest Duah, Zachary VanGundy, Yong Li, Ming Poi, Avinash K. Persaud, Nicholas E. Long, Thomas J. Magliery
Publikováno v:
Bioanalysis. 11(6)
Aim: To develop and validate a reliable, robust and efficient assay to detect and quantify biologic compounds in vitro and in vivo during early stage of a biotherapeutic agent discovery. Methodology & results: An enrichment-free immunoassay method wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2781d5b75ec3905e3f77646853b3740
https://pubmed.ncbi.nlm.nih.gov/30892061
https://pubmed.ncbi.nlm.nih.gov/30892061
Autor:
Thomas J. Magliery, Timothy J. Grunkemeyer, Kiran Kumar Doddapaneni, David G. Mata, Srividya Murali
Publikováno v:
Biochemistry.
The mammalian protein paraoxonase-1 (PON1) has been explored as a promising bioscavenger treatment for organophosphorus (OP) agent poisoning, but it is not active enough to protect against many agents. Engineering is limited because PON1's catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e223629c1eb949b3f4e73df760d87e41
https://pubmed.ncbi.nlm.nih.gov/30547569
https://pubmed.ncbi.nlm.nih.gov/30547569
Publikováno v:
ProteinsREFERENCES. 88(2)
The concept of consensus in multiple sequence alignments (MSAs) has been used to design and engineer proteins previously with some success. However, consensus design implicitly assumes that all amino acid positions function independently, whereas in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5571c3b05938f55e645b0764d484a3
https://pubmed.ncbi.nlm.nih.gov/31407418
https://pubmed.ncbi.nlm.nih.gov/31407418