Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Thomas J. Krzystek"'
Autor:
Thomas J. Krzystek, Rupkatha Banerjee, Layne Thurston, JianQiao Huang, Kelsey Swinter, Saad Navid Rahman, Tomas L. Falzone, Shermali Gunawardena
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-16 (2021)
Abstract Mitochondria are highly dynamic organelles with strict quality control processes that maintain cellular homeostasis. Within axons, coordinated cycles of fission-fusion mediated by dynamin related GTPase protein (DRP1) and mitofusins (MFN), t
Externí odkaz:
https://doaj.org/article/4ef3ab4bdd874811bcfea7ca9e7a30a2
Autor:
Joseph A. White, Thomas J. Krzystek, Hayley Hoffmar-Glennon, Claire Thant, Katherine Zimmerman, Gary Iacobucci, Julia Vail, Layne Thurston, Saad Rahman, Shermali Gunawardena
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-22 (2020)
Abstract Huntington’s disease (HD) is characterized by protein inclusions and loss of striatal neurons which result from expanded CAG repeats in the poly-glutamine (polyQ) region of the huntingtin (HTT) gene. Both polyQ expansion and loss of HTT ha
Externí odkaz:
https://doaj.org/article/224ce975c7d5489eb06e9d6481238e8d
Autor:
Thomas J. Krzystek, Joseph A. White, Rasika Rathnayake, Layne Thurston, Hayley Hoffmar-Glennon, Yichen Li, Shermali Gunawardena
Publikováno v:
Autophagy. 19:1199-1220
Atg5: Autophagy-related 5; Atg8a: Autophagy-related 8a; AL: autolysosome; AP: autophagosome; BAF1: bafilomycin A
Autor:
Shermali Gunawardena, Rupkatha Banerjee, Layne Thurston, JianQiao Huang, Thomas J. Krzystek, Kelsey Swinter, Tomás L. Falzone, Saad Navid Rahman
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Mitochondria are highly dynamic organelles with strict quality control processes that maintain cellular homeostasis. Within axons, coordinated cycles of fission-fusion mediated by dynamin related GTPase protein (DRP1) and mitofusins (MFN), together w
Autor:
Hayley Hoffmar-Glennon, Layne Thurston, Joseph A. White, Shermali Gunawardena, Claire N. Thant, Katherine Zimmerman, Julia Vail, Saad Navid Rahman, Thomas J. Krzystek, Gary J. Iacobucci
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-22 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-22 (2020)
Huntington’s disease (HD) is characterized by protein inclusions and loss of striatal neurons which result from expanded CAG repeats in the poly-glutamine (polyQ) region of the huntingtin (HTT) gene. Both polyQ expansion and loss of HTT have been s
Publikováno v:
Biochemistry. 58(48)
Transmembrane mucin-type glycoproteins can regulate signal transduction pathways. In yeast, signaling mucins regulate mitogen-activated protein kinase (MAPK) pathways that induce cell differentiation to filamentous growth (fMAPK pathway) and the resp