Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Thomas J. Kryzer"'
Autor:
Cristina Valencia-Sanchez, Andrew M Knight, M Bakri Hammami, Yong Guo, John R Mills, Thomas J Kryzer, Amanda L Piquet, Anik Amin, Morgan Heinzelmann, Claudia F Lucchinetti, Vanda A Lennon, Andrew McKeon, Sean J Pittock, Divyanshu Dubey
Publikováno v:
J Neurol Neurosurg Psychiatry
ObjectivesTo report the expanded neurological presentations and oncological associations of tripartite motif-containing protein 46 (TRIM46)-IgG seropositive patients.MethodsArchived sera/cerebrospinal fluid (CSF) were evaluated by tissue-based immuno
Autor:
A. Sebastian Lopez-Chiriboga, Thomas J. Kryzer, Madeleine Scharf, Andrew McKeon, Sean J. Pittock, Lars Komorowski, Josephe A. Honorat, Christopher J. Klein, Vanda A. Lennon, Shannon R. Hinson
Publikováno v:
Neurology
ObjectiveTo describe phenotypes, treatment response, and outcomes of autoimmunity targeting a synaptic vesicle coat protein, the neuronal (B2) form of adaptor protein–3 (AP3).MethodsArchived serum and CSF specimens (from 616,025 screened) harboring
Autor:
Andrew McKeon, Charles L. Howe, Yong Guo, Benjamin D. S. Clarkson, Andrew M. Knight, Sean J. Pittock, M. Bakri Hammami, Alicia Algeciras-Schimnich, John C. Cheville, Divyanshu Dubey, Claudia Lucchinnetti, Thomas J. Kryzer, Brian A. Costello, Vanda A. Lennon, Bradley C. Leibovich
Publikováno v:
Annals of neurologyReferences. 89(5)
OBJECTIVE This study was undertaken to describe a novel biomarker of germ cell tumor and associated paraneoplastic neurological syndrome (PNS). METHODS Archival sera from patients with germ cell tumor-associated PNS were evaluated. We identified a co
Autor:
Khashayarsha Khazaie, Patrick Andrews, James P. Fryer, Charles K. Kaufman, Caleigh Mandel-Brehm, James B. Thoreson, John C. Cheville, Michelle F. Devine, Divyanshu Dubey, Vanda A. Lennon, Manish J. Gandhi, Chadwick M. Hales, Charles L. Howe, John Mills, Kevin D. Pavelko, Joseph L. DeRisi, Caterina Giannini, Benjamin D. S. Clarkson, Michael R. Wilson, Andrew McKeon, Anastasia Zekeridou, Bradley C. Leibovich, Jenny J. Linnoila, Thomas J. Kryzer, Eoin P. Flanagan, Shannon R. Hinson, Matthew Torre, Jiraporn Jitprapaikulsan, Scott D.Z. Eggers, James E. Eaton, Jessica Sagen, Sean J. Pittock, Jorge C. Kattah
Publikováno v:
JAMA Neurol
Importance Recognizing the presenting and immunopathological features of Kelch-like protein-11 immunoglobulin G seropositive (KLHL11 IgG+) patients may aid in early diagnosis and management. Objective To describe expanding neurologic phenotype, cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017a19dfa48998a8ef14126e33288dc8
http://hdl.handle.net/11585/786035
http://hdl.handle.net/11585/786035
Autor:
Yong Guo, Eati Basal, Shannon R. Hinson, Thomas J. Kryzer, Andrew McKeon, Vanda A. Lennon, Sean J. Pittock, Claudia F. Lucchinetti, Divyanshu Dubey, Nicholas L. Zalewski, Eduardo E. Benarroch
Publikováno v:
Neurology
ObjectiveTo describe paraneoplastic neuronal intermediate filament (NIF) autoimmunity.MethodsArchived patient and control serum and CSF specimens were evaluated by tissue-based indirect immunofluorescence assay (IFA). Autoantigens were identified by
Autor:
Lillian M. Khan, Mckeon Andrew, Vanda A. Lennon, Sara E. Vazquez, Thomas J. Kryzer, Baouyen Tran, Joseph L. DeRisi, Caleigh Mandel-Brehm, Ian O. Bledsoe, Sean J. Pittock, Kelsey C. Zorn, Divyanshu Dubey, Samuel J. Pleasure, Michael R. Wilson, Hannah A. Sample, Brian D. O’Donovan
Publikováno v:
The New England journal of medicine, vol 381, iss 1
A 37-year-old man with a history of seminoma presented with vertigo, ataxia, and diplopia. An autoantibody specific for kelch-like protein 11 (KLHL11) was identified with the use of programmable phage display. Immunoassays were used to identify KLHL1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef60e857a303060bf8b1f745290a6d6
https://escholarship.org/uc/item/3hf463qf
https://escholarship.org/uc/item/3hf463qf
Autor:
Anastasia Zekeridou, Yong Guo, Sean J. Pittock, Thomas J. Kryzer, Vanda A. Lennon, Anhar Hassan, Claudia F. Lucchinetti, Andrew McKeon
Publikováno v:
Neurology. 93(8)
ObjectiveTo describe a novel antibody biomarker of neurologic paraneoplastic autoimmunity specific for phosphodiesterase 10A (PDE10A), a striatum-enriched phosphodiesterase, and to characterize the clinical phenotype of patients with PDE10A immunoglo
Autor:
Orna O'Toole, Margherita Milone, Metha Apiwattanakul, Sean J. Pittock, Vanda A. Lennon, Thomas J. Kryzer, James P. Fryer, Andrew McKeon
Publikováno v:
Muscle & Nerve
Introduction: Paraneoplastic autoantibody screening of 150,000 patient sera by tissue‐based immunofluorescence incidentally revealed 170 with unsuspected signal recognition particle (SRP) immunoglobulin G (IgG), which is a recognized biomarker of a
Autor:
Yasuteru Sano, Richard M. Ransohoff, Thomas J. Kryzer, Fumitaka Shimizu, Gregory P. Owens, Vanda A. Lennon, Yukio Takeshita, Kristin Schaller, Anne C. Cotleur, Debra Kellner, Jeffrey Bennett, Birgit Obermeier, Takashi Kanda
Publikováno v:
Science Translational Medicine. 9
Neuromyelitis optica (NMO) is an inflammatory disorder mediated by antibodies to aquaporin-4 (AQP4) with prominent blood-brain barrier (BBB) breakdown in the acute phase of the disease. Anti-AQP4 antibodies are produced mainly in the periphery, yet t
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(21)
Aquaporin-4 (AQP4) water channel-specific IgG distinguishes neuromyelitis optica (NMO) from multiple sclerosis and causes characteristic immunopathology in which central nervous system (CNS) demyelination is secondary. Early events initiating the pat