Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas J. Kakuk"'
Autor:
Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner, Joseph W. Strohbach, Ruben A. Tommasi, Paul D. Johnson, Paul A. Aristoff, Thomas M. Judge, Ronald B. Gammill, Jeanette K. Morris, Karen R. Romines, Robert A. Chrusciel, Roger R. Hinshaw, Kong-Teck Chong, W. Gary Tarpley, Susan M. Poppe, David E. Slade, Janet C. Lynn, Miao-Miao Horng, Paul K. Tomich, Eric P. Seest, Lester A. Dolak, W. Jeffrey Howe, Gina M. Howard, Francis J. Schwende, Lisa N. Toth, Guy E. Padbury, Grace J. Wilson, Lihua Shiou, Gail L. Zipp, Karen F. Wilkinson, Bob D. Rush, Mary J. Ruwart, Kenneth A. Koeplinger, Zhiyang Zhao, Serena Cole, Renee M. Zaya, Thomas J. Kakuk, Musiri N. Janakiraman, Keith D. Watenpaugh
Publikováno v:
Journal of Medicinal Chemistry. 39:4349-4353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7de8a7ff5c653756fe8a0d71028a5b
https://doi.org/10.1021/jm960541s
https://doi.org/10.1021/jm960541s
Publikováno v:
Toxicological Sciences. 26:246-257
Tirilazad Mesylate—Effects of the 21-Aminosteroid on the Lymphoid System of Laboratory Animals: A Comparison with the Glucocorticoid Methylprednisolone. Jackson, T. A., Ochoa, R., and Kakuk, T. J. (1995). Fundam. Appl. Toxicol. 26, 246-257. Four-we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67f1039514a97d8af198d9ef60adb21
https://doi.org/10.1093/toxsci/26.2.246
https://doi.org/10.1093/toxsci/26.2.246
Publikováno v:
Pharmaceutical Research. :80-83
Ditekiren is a pseudo-octapeptide being developed as an inhibitor of human renin. Preclinical drug safety studies with this drug involved continuous iv infusions through indwelling catheters in the right internal jugular vein of the cynomolgus monkey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0540b344c7051af92af001fd2db0b26b
https://doi.org/10.1023/a:1015886424586
https://doi.org/10.1023/a:1015886424586
Autor:
G.L Zipp, Lester A. Dolak, K. D. Watenpaugh, W.-Z Zhong, R. R. Hinshaw, C.W Johnson, David J. Anderson, L. S. Banitt, Johnson Paul D, Paul A. Aristoff, G.M Howard, M.N. Janakiraman, R J Reischer, Howe Wj, Harvey Irving Skulnick, Theresa M. Schwartz, L. N. Toth, K.R Wilkinson, Bob D. Rush, Karen Rene Romines, J. C. Lynn, Serena L. Cole, M. G. Williams, Eric P. Seest, Renee M. Zaya, Joel Morris, Chong Kt, Thomas J. Kakuk, R.J Dalga, K D Lovasz, Tomich Pk, M.‐M. Horng, P.L Possert, F.J Schwende
Publikováno v:
Journal of medicinal chemistry. 40(7)
Recently, cyclooctylpyranone derivatives with m-carboxamide substituents (e.g. 2c) were identified as potent, nonpeptidic HIV protease inhibitors, but these compounds lacked significant antiviral activity in cell culture. Substitution of a sulfonamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc7a130b4b392170feddcbcdbfa6abe
https://pubmed.ncbi.nlm.nih.gov/9089336
https://pubmed.ncbi.nlm.nih.gov/9089336
Autor:
Roger J. Brideau, Wells Pa, Zhang Jy, Serena L. Cole, Roberts Ed, Thomas J. Kakuk, Kenneth F. Soike, Renee M. Zaya, M.W. Wathen
Publikováno v:
The Journal of infectious diseases. 167(3)
Human respiratory syncytial virus (RSV) is the leading cause of severe bronchiolitis and pneumonia in infants. RSV vaccine development has been stifled for the past 23 years because infants vaccinated with formalin-inactivated (FI) RSV have experienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e9419c7a0ae5025c2c8f34e4f2add1
https://pubmed.ncbi.nlm.nih.gov/8440926
https://pubmed.ncbi.nlm.nih.gov/8440926
Autor:
Thomas J. Kakuk, Michael W. Wathen, Renee M. Zaya, Edward C. Hausknecht, Serena L. Cole, Roger J. Brideau
Publikováno v:
The Journal of infectious diseases. 163(3)
The cotton rat model of human respiratory syncytial virus (RSV) infection was used to study the safety and efficacy of a chimeric FG glycoprotein that was expressed in insect cells using a baculovirus vector. Histologic and virologic examination of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ccc02640d175f9e132caf86135abd6
https://pubmed.ncbi.nlm.nih.gov/1995720
https://pubmed.ncbi.nlm.nih.gov/1995720
Autor:
Thomas J. Kakuk, Walter H. Hsu
Publikováno v:
Toxicology and Applied Pharmacology. 73:411-415
Pupillary and cardiac responses to the insecticide/acaricide amitraz (0.03 to 1.0 mg/kg, iv) and chlordimeform (0.03 to 10.0 mg/kg, iv), as well as the alpha 2-adrenergic agonists clonidine (1 to 30 micrograms/kg, iv) and xylazine (10 to 300 microgra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e260dd44d2739d0f151fc96e48f564
https://doi.org/10.1016/0041-008x(84)90093-0
https://doi.org/10.1016/0041-008x(84)90093-0
Autor:
Thomas J. Kakuk, Fred R. Frank, Todd E. Weddon, Ben R. Burmester, H. Graham Purchase, Carlos H. Romero
Publikováno v:
Avian Diseases. 21:280
Duplicate trials with mibolerone at a dose of 1 microng/g of diet for the first 49 days of age reduced the incidence of lymphoid leukosis (LL) significantly (P less than .005) in chickens inoculated as day-old chicks with Rous-associated virus type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::942b5e1e40f79ff093ba34187e7e99cc
https://doi.org/10.2307/1589347
https://doi.org/10.2307/1589347
Autor:
Carl Olson, Thomas J. Kakuk
Publikováno v:
Avian Diseases. 11:336
Tumor growth and incidence may be related to certain dietary components and the plane of nutrition. Some workers (1,6,7,11,13) have indicated that high levels of neutral fat in the diet may cause a more rapid growth of several neoplasms. This finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec15c1378500b26d3711c8674f279bce
https://doi.org/10.2307/1588177
https://doi.org/10.2307/1588177