Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas J. Grundy"'
Autor:
Andrew M. K. Law, Laura Rodriguez de la Fuente, Thomas J. Grundy, Guocheng Fang, Fatima Valdes-Mora, David Gallego-Ortega
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Over 90% of potential anti-cancer drug candidates results in translational failures in clinical trials. The main reason for this failure can be attributed to the non-accurate pre-clinical models that are being currently used for drug development and
Externí odkaz:
https://doaj.org/article/95fb65fb5899476aa52b33cf93b7182e
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/0ec86de194b7479ebb7bb33449e96200
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Externí odkaz:
https://doaj.org/article/445809e39596411894c241e66afcfafe
Autor:
Nadine Grummel, Carolin C. Hack, Christoph Mark, Geraldine M. O'Neill, Richard Gerum, Markus Eckstein, Ben Fabry, Reiner Strick, Pamela L. Strissel, Matthias W. Beckmann, Thomas J Grundy, David Böhringer, Julian Steinwachs
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Autor:
Ben Fabry, David Böhringer, Christoph Mark, Carolin C. Hack, Geraldine M. O'Neill, Reiner Strick, Thomas J Grundy, Matthias W. Beckmann, Richard Gerum, Nadine Grummel, Julian Steinwachs, Markus Eckstein, Pamela L. Strissel
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Autor:
Markus Eckstein, Richard Gerum, Nadine Grummel, Julian Steinwachs, Matthias W. Beckmann, Pamela L. Strissel, Thomas J Grundy, Christoph Mark, Ben Fabry, Reiner Strick, Carolin C. Hack, Geraldine M. O'Neill, David Böhringer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70d2ca52302f16f4b8e69807c191ee5f
https://doi.org/10.7554/elife.51912.sa2
https://doi.org/10.7554/elife.51912.sa2
Autor:
Ben Fabry, Christoph Mark, Julian Steinwachs, Geraldine M. O'Neill, Thomas J Grundy, David Böhringer
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554a722e79e9ff248be31a1af86aca40
https://doi.org/10.1101/654079
https://doi.org/10.1101/654079
Autor:
Christoph Mark, Geraldine M. O'Neill, Ben Fabry, Pamela L. Strissel, David Böhringer, Thomas J Grundy, Reiner Strick, Nadine Grummel
Publikováno v:
Biophysical Journal. 118:606a
Autor:
Thomas J Grundy, Bryan W. Day, Geraldine M. O'Neill, Ben Fabry, Brett W. Stringer, Kaitlyn Rose Griffin, Ellen J de Leon, Justin J. Cooper-White
Publikováno v:
Scientific Reports
The ability of cancer cells to sense external mechanical forces has emerged as a significant factor in the promotion of cancer invasion. Currently there are conflicting reports in the literature with regard to whether glioblastoma (GBM) brain cancer