Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thomas J. Griffin"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 6, Pp 1310-1316 (2019)
Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaral
Externí odkaz:
https://doaj.org/article/fbfd1a19c87b421c8195c1660aafc381
Autor:
Robert T Cartee, Ann Thanawastien, Thomas J Griffin Iv, John J Mekalanos, Stephan Bart, Kevin P Killeen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007912 (2020)
BACKGROUND:Typhoid fever remains a significant cause of morbidity and mortality in developing countries especially in children ≤5 years old. Although the widely available unconjugated Vi polysaccharide vaccines are efficacious, they confer limited,
Externí odkaz:
https://doaj.org/article/2a50a6751c374121b9263e76863bbf71
Autor:
Thanawastien, Ann, Cartee, Robert T., IV, Thomas J. Griffin, Killeen, Kevin P., Mekalanos, John J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Mar 01. 112(10), E1143-E1151.
Externí odkaz:
https://www.jstor.org/stable/26461797
Autor:
John J. Mekalanos, Kevin P. Killeen, Robert T. Cartee, Thomas J. Griffin, Stephan Bart, Ann Thanawastien
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007912 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Typhoid fever remains a significant cause of morbidity and mortality in developing countries especially in children ≤5 years old. Although the widely available unconjugated Vi polysaccharide vaccines are efficacious, they confer limited,
Publikováno v:
Hum Vaccin Immunother
Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaral
Capsular polysaccharides are the primary antigenic components involved in protective immunity against encapsulated bacterial pathogens. Although immunization of adolescents and adults with polysaccharide antigens has reduced pathogen disease burden,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313577a7d8e6b1d59143a7dfe6c093e7
https://europepmc.org/articles/PMC4364189/
https://europepmc.org/articles/PMC4364189/
Autor:
Thomas J. Griffin, Sarah Friedman, Nigel D. F. Grindley, Miriam Braunstein, William R. Jacobs, Jordan Kriakov
Publikováno v:
Journal of Bacteriology. 182:2732-2740
Mycobacterium tuberculosis continues to pose a serious health threat to people throughout the world. With an estimated 2.9 million people having died from tuberculosis in 1997, M. tuberculosis remains the infectious agent responsible for the most dea
Autor:
Linda Parsons, Andres E. Leschziner, Keith M. Derbyshire, Thomas J. Griffin, Justine DeVost, Nigel D. F. Grindley
Publikováno v:
Nucleic Acids Research. 27:3859-3865
We have explored the potential of the Tn 552 in vitro transposition reaction as a genetic tool. The reaction is simple (requiring a single protein component), robust and efficient, readily producing insertions into several percent of target DNA. Most
Publikováno v:
Proceedings of the National Academy of Sciences. 95:7345-7350
The Tn 552 transposase, a member of the DDE superfamily of transposase and retroviral integrase proteins, has been expressed in soluble form. The purified protein performs concerted strand transfer in vitro , efficiently pairing two preprocessed tran
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology. 70:420-424
A case of IP in a 16-year-old girl has been presented. This patient manifested classic ectodermal and mesodermal anomalies. We present this case to illustrate a rare etiologic factor in the development of dentofacial deformities that can be treated i