Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Thomas J. Eddinger"'
Autor:
John F LaDisa, Serdar Bozdag, Jessica Olson, Ramani Ramchandran, Judy R Kersten, Thomas J Eddinger
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133356 (2015)
Coarctation of the aorta (CoA) is a constriction of the proximal descending thoracic aorta and is one of the most common congenital cardiovascular defects. Treatments for CoA improve life expectancy, but morbidity persists, particularly due to the de
Externí odkaz:
https://doaj.org/article/e3256136a17b40e0ad70195e948d3164
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74608 (2013)
Regulation of myosin light chain phosphatase (MLCP) via protein kinase C (PKC) and the 17 kDa PKC-potentiated inhibitor of myosin light chain phosphatase (CPI-17) has been reported as a Ca(2+) sensitization signaling pathway in smooth muscle (SM), an
Externí odkaz:
https://doaj.org/article/774945c6cc324bfeb7762cf0741ac67c
Autor:
Michael E. Mitchell, Kathryn Repp, Mary Krolikowski, Donna K. Mahnke, Kathleen Bazan, Jesse W. Gerringer, Brandon J. Wegter, Adrian Zietara, Mary Goetsch, Karl Stamm, Thomas J. Eddinger, Oleg Palygin, John F. LaDisa, Abdel A. Alli, Aoy Tomita-Mitchell
Publikováno v:
Physiol Genomics
Coarctation of the aorta (CoA) is a common congenital cardiovascular (CV) defect characterized by a stenosis of the descending thoracic aorta. Treatment exists, but many patients develop hypertension (HTN). Identifying the cause of HTN is challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee1e34954427f7f8c8371d37c655128
https://pubmed.ncbi.nlm.nih.gov/31002586
https://pubmed.ncbi.nlm.nih.gov/31002586
Autor:
Thomas J. Eddinger
Publikováno v:
American journal of physiology. Renal physiology. 313(4)
to examine biomechanical properties of soft biological materials such as smooth muscle, tissues secured between a force transducer and micrometer are often preconditioned by subjecting them to a protocol involving sequential stretch-release cycles wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f269adbfeeafaa47f11ed90153b50
https://pubmed.ncbi.nlm.nih.gov/28356291
https://pubmed.ncbi.nlm.nih.gov/28356291
Autor:
Thomas J. Eddinger
Publikováno v:
The Anatomical Record. 297:1734-1746
Smooth muscle (SM) tissue is a complex organization of multiple cell types and is regulated by numerous signaling molecules (neurotransmitters, hormones, cytokines, etc.). SM contractile function can be regulated via expression and distribution of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca02dd81076fe61bfa394116f2982968
https://doi.org/10.1002/ar.22970
https://doi.org/10.1002/ar.22970
Publikováno v:
CBE Life Sciences Education
Students score higher on postexam assessment topics learned via peer-reviewed writing, or when they correct exam questions initially answered incorrectly, compared with their nonparticipating peers.
Writing assignments, including note taking and
Writing assignments, including note taking and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06b1ae3337bc107be0caedb0c1b95eb
https://doi.org/10.1187/cbe.13-05-0097
https://doi.org/10.1187/cbe.13-05-0097
Autor:
Thomas J. Eddinger
Publikováno v:
Vascular Smooth Muscle: Structure and Function in Health and Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb35b0cd8bdd708976e36efb55f1aa7
https://doi.org/10.1142/9789813144064_0002
https://doi.org/10.1142/9789813144064_0002
Autor:
David C. Wendell, John F. LaDisa, Thomas J. Eddinger, Jeffrey M. Toth, Arjun Menon, Hongfeng Wang
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H1304-H1318
Coarctation of the aorta (CoA) is associated with substantial morbidity despite treatment. Mechanically induced structural and functional vascular changes are implicated; however, their relationship with smooth muscle (SM) phenotypic expression is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223346a63afa09c78acb1ee1c3b98f4b
https://doi.org/10.1152/ajpheart.00420.2012
https://doi.org/10.1152/ajpheart.00420.2012
Autor:
Arthur S. Rovner, Amy S. Miner, Paul H. Ratz, Daniel P. Meer, Thomas J. Eddinger, Joel T. Meehl
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 320:865-870
Blebbistatin is reported to be a selective and specific small molecule inhibitor of the myosin II isoforms expressed by striated muscles and nonmuscle (IC(50) = 0.5-5 microM) but is a poor inhibitor of purified turkey smooth muscle myosin II (IC(50)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b33e860f0aa6d9d10ce4a9e23267ad6
https://doi.org/10.1124/jpet.106.109363
https://doi.org/10.1124/jpet.106.109363
Publikováno v:
British Journal of Pharmacology. 137:983-992
The degree to which the RhoA kinase (ROK) blockers, Y-27632 (1 μM) and HA-1077 (10 μM), and the PKC blocker, GF-109203X (1 μM), reduced force produced by carbachol, a muscarinic receptor agonist, and phenylephrine, an α-adrenoceptor agonist, was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::487c9736ba6253fdb072ff6b44d8ea41
https://doi.org/10.1038/sj.bjp.0704952
https://doi.org/10.1038/sj.bjp.0704952