Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Thomas J. Dougherty"'
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Biogenesis of the outer membrane of Gram-negative bacteria depends on dedicated macromolecular transport systems. The LolABCDE proteins make up the machinery for lipoprotein trafficking from the inner membrane (IM) across the periplasm to th
Externí odkaz:
https://doaj.org/article/924bf0069511460596ca881bfcf7b2d0
Publikováno v:
Journal of Bacteriology
A key set of lipoprotein transport components, LolCDE, were inhibited by both a small molecule as well as genetic downregulation of their expression. The data show a unique signature in the Pseudomonas aeruginosa transcriptome in response to perturba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c0249e05824ff7d945cf13af44432a
https://doi.org/10.1128/jb.00452-20
https://doi.org/10.1128/jb.00452-20
Autor:
Thomas J. Dougherty, Barbara W. Henderson, Samuel Schwartz, James W. Winkelman, Richard L. Lipson
Publikováno v:
Photodynamic Therapy ISBN: 9781003066897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9e71aee8bafab1393a254f71e07dbd
https://doi.org/10.1201/9781003066897-1
https://doi.org/10.1201/9781003066897-1
Publikováno v:
Journal of Bacteriology
In Gram-negative bacteria, a dedicated machinery consisting of LolABCDE components targets lipoproteins to the outer membrane. We used a previously identified small-molecule inhibitor of the LolCDE complex of Escherichia coli to assess the global tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213654e14a051fa158b5185a5f1886f1
https://doi.org/10.1128/jb.00502-16
https://doi.org/10.1128/jb.00502-16
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00194-19 (2019)
mBio
mBio, Vol 10, Iss 2, p e00194-19 (2019)
mBio
Gram-negative bacteria build their outer membranes (OM) from components that are initially located in the inner membrane (IM). A fraction of lipoproteins is transferred to the OM by the transport machinery consisting of LolABCDE proteins. Our work de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d379c2ebad588a75aa26fedf6cc0560
https://doi.org/10.1128/mbio.00194-19
https://doi.org/10.1128/mbio.00194-19
Autor:
David E. Ehmann, Jason Thresher, Asha S. Nayar, Ning Gao, Folkert Reck, Adam B. Shapiro, Thomas J. Dougherty
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:331-337
In a previous report (T. J. Dougherty, A. Nayar, J. V. Newman, S. Hopkins, G. G. Stone, M. Johnstone, A. B. Shapiro, M. Cronin, F. Reck, and D. E. Ehmann, Antimicrob Agents Chemother 58:2657–2664, 2014), a novel bacterial type II topoisomerase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2632fda9d5d600daf271f08bf6541e
https://doi.org/10.1128/aac.04077-14
https://doi.org/10.1128/aac.04077-14
The main objective of this book is to present the recent applications of photodynamic therapy (PDT) in treating cancer and other diseases. The limitations associated with current PDT agents, and the synthetic designs that have been used in various la
Autor:
Thomas J. Dougherty, Michael J. Pucci
Publikováno v:
Current opinion in microbiology. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f855f46e6d6b892f2007eb716a9738d
https://pubmed.ncbi.nlm.nih.gov/27567402
https://pubmed.ncbi.nlm.nih.gov/27567402
Publikováno v:
Handbook of Photodynamic Therapy: Updates on Recent Applications of Porphyrin-Based Compounds
Part 1: Multifunctional Agents for Cancer-Imaging and Photodynamic Therapy: Monomers vs. Polyacrylamide-Based Nanoplatforms (Aimee Marko, Nayan J Patel, Penny Joshi, Joseph R Missert and Ravindra K Pandey) Design and Synthesis of Photosensitizers-pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de4e85bfc7b3be85d28e2c3b393df591
https://doi.org/10.1142/9774
https://doi.org/10.1142/9774
Autor:
Michele T. Cooper, Barbara W. Henderson, Shyam Allamaneni, Hector R. Nava, Gregory E. Wilding, Wei Tan, Thomas J. Dougherty
Publikováno v:
Lasers in Surgery and Medicine. 43:705-712
Background and Objectives Photodynamic therapy (PDT) with porfimer sodium, FDA approved to treat premalignant lesions in Barrett’s esophagus, causes photosensitivity for 6-8 weeks. HPPH (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a) shows minim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92ec9f057b2bff10764d40fa3988657
https://doi.org/10.1002/lsm.21112
https://doi.org/10.1002/lsm.21112