Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Thomas J. Carroll"'
Autor:
Akhil Dondapati, Thomas J. Carroll, Samuel Florentino, Jonathan Minto, Warren C. Hammert, Bilal Mahmood
Publikováno v:
Journal of Orthopaedic Reports, Vol 4, Iss 1, Pp 100451- (2025)
Introduction: Our study sought to determine outcomes of patients who underwent non-operative and surgical treatment of distal biceps ruptures utilizing both PROMIS and Patient Acceptable Symptoms State (PASS). Methods: This study was a 7-year study p
Externí odkaz:
https://doaj.org/article/cde0ee63c7ba48068227bd94b57074b7
Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
Autor:
Zhiguo Chen, Stephen Li, Juan Mo, Eric Hawley, Yong Wang, Yongzheng He, Jean-Philippe Brosseau, Tracey Shipman, D. Wade Clapp, Thomas J. Carroll, Lu Q. Le
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Schwannomas are tumors of the Schwann cells that cause chronic pain, numbness, and potentially life-threatening impairment of vital organs. Despite the identification of causative genes, including NF2 (Merlin), INI1/SMARCB1, and LZTR1, the exact mole
Externí odkaz:
https://doaj.org/article/c7767e2f0eef47f9a10e9ecb1c27e92d
Autor:
Ebony M. Flowers, Jessica Sudderth, Lauren Zacharias, Glenda Mernaugh, Roy Zent, Ralph J. DeBerardinis, Thomas J. Carroll
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Polycystic kidney disease (PKD) is characterized by the formation of large fluid-filled cysts. Here Flowers and colleagues show that loss of Lkb1, downregulated in PKD, renders kidney cells dependent on glutamine for growth, and suggest that inhibiti
Externí odkaz:
https://doaj.org/article/2bb7dc69954d4d07aea6f8ecaf917710
Autor:
Sean T. Bailey, Aleisha M. Smith, Jordan Kardos, Sara E. Wobker, Harper L. Wilson, Bhavani Krishnan, Ryoichi Saito, Hyo Jin Lee, Jing Zhang, Samuel C. Eaton, Lindsay A. Williams, Ujjawal Manocha, Dorien J. Peters, Xinchao Pan, Thomas J. Carroll, Dean W. Felsher, Vonn Walter, Qing Zhang, Joel S. Parker, Jen Jen Yeh, Richard A. Moffitt, Janet Y. Leung, William Y. Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Renal cell carcinoma (RCC) is a common and aggressive malignancy. Here, the authors generate two mouse models of the most common RCC subtypes: the human papillary RCC throughMYC activation and clear cell RCC through MYC activation combined with Vhl a
Externí odkaz:
https://doaj.org/article/0f0c33aaa830403a92bded52b464aea5
Autor:
Joseph C Maggiore, Ryan LeGraw, Aneta Przepiorski, Jeremy Velazquez, Christopher Chaney, Evan Streeter, Anne Silva-Barbosa, Jonathan Franks, Joshua Hislop, Alex Hill, Haojia Wu, Katherine Pfister, Sara E Howden, Simon C Watkins, Melissa Little, Benjamin Humphreys, Alan Watson, Donna B Stolz, Samira Kiani, Alan J Davidson, Thomas J. Carroll, Ondine J. Cleaver, Sunder Sims-Lucas, Mo R Ebrahimkhani, Neil A Hukriede
Vascularization plays a critical role in organ maturation and cell type development. Drug discovery, organ mimicry, and ultimately transplantation in a clinical setting thereby hinges on achieving robust vascularization of in vitro engineered organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a832bb2fd956b83cba53f6fdf775582
https://doi.org/10.1101/2023.05.30.542848
https://doi.org/10.1101/2023.05.30.542848
Publikováno v:
Cureus.
Autor:
Lu Q. Le, Thomas J. Carroll, Justin Guinney, Sara J.C. Gosline, Robert J. Allaway, Jonathan M. Cooper, Chung-Ping Liao, Yong Wang, Tracey Shipman, Jean-Philippe Brosseau, Juan Mo, Zhiguo Chen
Neurofibromatosis type 1 (NF1) is a cancer predisposition disorder that results from inactivation of the tumor suppressor neurofibromin, a negative regulator of RAS signaling. Patients with NF1 present with a wide range of clinical manifestations, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c56b657e5509d39827c991466ae76b1
https://doi.org/10.1158/2159-8290.c.6546817.v1
https://doi.org/10.1158/2159-8290.c.6546817.v1
Autor:
Thomas J Carroll, Marc O'Donnell
Publikováno v:
Cureus.
Publikováno v:
J Mol Biol
Identification of genes that reliably mark distinct cell types is key to leveraging single-cell RNA sequencing to better understand organismal biology. Such genes are usually chosen by measurement of differential expression between groups of cells an
Autor:
Keri A. Drake, Christopher Chaney, Mohita Patel, Amrita Das, Julia Bittencourt, Martin Cohn, Thomas J. Carroll
Publikováno v:
Journal of the American Society of Nephrology : JASN.
The embryonic renal stroma consists of multiple molecularly distinct cell subpopulations, the functional significance of which is largely unknown. Previous work has demonstrated that the transcription factors YAP and TAZ play roles in the development