Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Thomas J. Campbell"'
Autor:
Robert G. Dean, Thomas J. Campbell
Publikováno v:
Springer Handbook of Ocean Engineering ISBN: 9783319166483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e8ff7bfea6ac429e9984e23fcb34568
https://doi.org/10.1007/978-3-319-16649-0_29
https://doi.org/10.1007/978-3-319-16649-0_29
Publikováno v:
Molecular plant. 9(4)
A genome-wide screen for mutants showing altered brassinosteroid (BR) sensitivity or bri1-like phenotypes resulted in the identification of two new mutant alleles of TWISTED DWARF 1 (TWD1), twd1-4, and twd1-5. Previous studies indicated that TWD1, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b4f04224b0a300f68c5be093d71cd4
https://pubmed.ncbi.nlm.nih.gov/26802250
https://pubmed.ncbi.nlm.nih.gov/26802250
Autor:
Gilbert Diaz, Lee C. Preusser, Ann Mikhail, Christopher A. Ogiela, Lynch John K, Philip R. Kym, Lisa M. Hernández, Dariusz Wodka, Gang Zhao, Doug H. Falls, Eugene N. Bush, James S. Polakowski, Andrew S. Judd, Robin Shapiro, Hing L. Sham, James J. Napier, Christine A. Collins, Kennan C. Marsh, Victoria Knourek-Segel, Glenn A. Reinhart, Thomas J Campbell, Sevan Brodjian, Michael E. Brune, Brian A. Droz, Mathew M. Mulhern, Kathryn Houseman, Regina M. Reilly, Brian D. Dayton, Ryan M. Fryer, James T. Limberis, Rajesh R. Iyengar, Freeman Jennifer C
Publikováno v:
Journal of Medicinal Chemistry. 49:6569-6584
Evaluation of multiple structurally distinct series of melanin concentrating hormone receptor 1 antagonists in an anesthetized rat cardiovascualar assay led to the identification of a chromone-2-carboxamide series as having excellent safety against t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b667ab564d57ac2f27112dd9382a72ab
https://doi.org/10.1021/jm060683e
https://doi.org/10.1021/jm060683e
Autor:
Hing L. Sham, Regina M. Reilly, Freeman Jennifer C, Lee C. Preusser, Mathew M. Mulhern, Dariusz Wodka, Kennan C. Marsh, Andrew S. Judd, Jason A. Segreti, Ryan M. Fryer, Rajesh R. Iyengar, Gang Zhao, Lynch John K, Brian D. Dayton, Sevan Brodjian, Anil Vasudevan, Lisa M. Hernández, James J. Napier, Christine A. Collins, Seble Wagaw, Glenn A. Reinhart, Thomas J Campbell, Andrew J. Souers, Ju Gao, James S. Polakowski, Philip R. Kym
Publikováno v:
Journal of Medicinal Chemistry. 49:2339-2352
An inactin-anesthetized rat cardiovascular (CV) assay was employed in a screening mode to triage multiple classes of melanin-concentrating hormone receptor 1 (MCHr1) antagonists. Lead identification was based on a compound profile producing high drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619be8483639af871b30640981ceee6d
https://doi.org/10.1021/jm0512286
https://doi.org/10.1021/jm0512286
Autor:
Bryan F. Cox, Thomas J Campbell, James S. Polakowski, Richard T Layer, Nathan L. Lubbers, Jeannine Moore, Garrett J. Gross, Grzegorz Bulaj
Publikováno v:
Journal of Cardiovascular Pharmacology. 46:141-146
CGX-1051 is a synthetic version of a peptide originally isolated from the venom of cone snails. In the present studies, we tested the potential cardioprotective effect of CGX-1051 in a rat and dog model of myocardial ischemia/reperfusion. CGX-1051 wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eb60d06ca497a371d7744e2bbfb085
https://doi.org/10.1097/01.fjc.0000167015.84715.27
https://doi.org/10.1097/01.fjc.0000167015.84715.27
Autor:
Thomas J. Campbell, Emmanuel Liscum
Publikováno v:
The Plant Cell. 13:1704-1710
Light has long been known to be an important signal for plant development, influencing nearly all aspects of the life cycle from germination to flowering. From May 30 to June 2, 2001, the mechanisms by which plants perceive and respond to their light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ca1ea937423cf8ab0d2197da30a66a
https://doi.org/10.1105/tpc.13.8.1704
https://doi.org/10.1105/tpc.13.8.1704
Autor:
Chang Zhu, James S. Polakowski, Prisca Honore, Murali Gopalakrishnan, Thomas J Campbell, Thomas Shaughnessy, John Malysz, Chih-Hung Lee
Publikováno v:
Biochemical pharmacology. 82(8)
Nicotinic acetylcholine receptors (nAChRs) function as ligand-gated ion channels activated by the neurotransmitter acetylcholine. Gene knockout and antisense studies coupled with pharmacological studies with nAChR agonists have documented a role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4829a044dde9d6b3fed4b69d60f61871
https://pubmed.ncbi.nlm.nih.gov/21763685
https://pubmed.ncbi.nlm.nih.gov/21763685
Autor:
Andrew J. King, Lee C. Preusser, Anita J Kempf-Grote, Richard A. Nelson, Gary A. Gintant, James S. Polakowski, Kennan C. Marsh, Thomas J Campbell, Bryan F. Cox, Scott W. Mittelstadt
Publikováno v:
Journal of cardiovascular pharmacology. 54(6)
Torcetrapib is a cholesteryl ester transfer protein inhibitor with an undesired response of increasing arterial pressure in humans. Pressor responses to torcetrapib have been demonstrated in multiple preclinical species. However, these studies have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa74b9c4a9cf1c8880d9c732cee065b2
https://pubmed.ncbi.nlm.nih.gov/19770671
https://pubmed.ncbi.nlm.nih.gov/19770671
Autor:
Jinshyun R Wu-Wong, Thomas J Campbell, Paul E Kroeger, William Noonan, Jason Segreti, Xiaoan Ruan, Masaki Nakane, Kristin A Brooks, James S Polakowski, Bryan F Cox
Publikováno v:
Circulation. 118
Vitamin D receptor (VDR) activation therapy is associated with cardiovascular/survival benefit in chronic kidney disease (CKD), but the mechanism of action is not well understood. The aim of this study is to investigate how uremia affects gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f90a29cb8fcb793ceedc9b5bc7f003
https://doi.org/10.1161/circ.118.suppl_18.s_336
https://doi.org/10.1161/circ.118.suppl_18.s_336
Autor:
James S. Polakowski, Xiaohong Song, R.B. Diebold, Gui-Dong Zhu, Saul H. Rosenberg, Ran Guan, Gary Gintant, Jianchun Gong, Eric F. Johnson, Amanda M. Olson, Qun Li, Jennifer J. Bouska, Xuesong Liu, Keith W. Woods, Vincent S. Stoll, Thomas J Campbell, Klinghofer, Sheela A. Thomas, Mulugeta Mamo, Ruth L. Martin, Thomas D. Penning, Vincent L. Giranda, T. Li, Kennan C. Marsh, Viraj B. Gandhi, Yan Luo
Publikováno v:
Journal of medicinal chemistry. 50(13)
Compound 7 was identified as a potent (IC50 = 14 nM), selective, and orally bioavailable (F = 70% in mouse) inhibitor of protein kinase B/Akt. While promising efficacy was observed in vivo, this compound showed effects on depolarization of Purkinje f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c829391bbcc39a3fdfbe77a4a0ec408a
https://pubmed.ncbi.nlm.nih.gov/17523610
https://pubmed.ncbi.nlm.nih.gov/17523610