Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Thomas J. Bolt"'
Autor:
Joseph P. Dexter, Pramit Chaudhuri, Patrick J. Burns, Elizabeth D. Adams, Thomas J. Bolt, Adriana Cásarez, Jeffrey H. Flynt, Kyle Li, James F. Patterson, Ariane Schwartz, Scott Shumway
Publikováno v:
Journal of Open Humanities Data, Vol 10, Pp 14-14 (2024)
Characterization of intertextual references among authors is fundamental for the study of Latin literature. In this paper, we describe a large-scale intertextuality dataset compiled from three modern commentaries on Valerius Flaccus’ epic poem Argo
Externí odkaz:
https://doaj.org/article/6ca7081dc5f94558b363187cd8080440
Autor:
Peter H. Moons, Floor ter Braak, Frank F. J. de Kleijne, Bart Bijleveld, Sybren J. R. Corver, Kas J. Houthuijs, Hero R. Almizori, Giel Berden, Jonathan Martens, Jos Oomens, Paul B. White, Thomas J. Boltje
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Attaining complete anomeric control is still one of the biggest challenges in carbohydrate chemistry. Glycosyl cations such as oxocarbenium and dioxanium ions are key intermediates of glycosylation reactions. Characterizing these highly-reac
Externí odkaz:
https://doaj.org/article/03d3bba4f2e34c4c9342a546b695ae9d
Autor:
Kirsty Hodgson, Margarita Orozco-Moreno, Emily Archer Goode, Matthew Fisher, Rebecca Garnham, Richard Beatson, Helen Turner, Karen Livermore, Yuhan Zhou, Laura Wilson, Eline A. Visser, Johan FA. Pijnenborg, Nienke Eerden, Sam J. Moons, Emiel Rossing, Gerald Hysenaj, Rashi Krishna, Ziqian Peng, Kyla Putri Nangkana, Edward N. Schmidt, Adam Duxfield, Ella P. Dennis, Rakesh Heer, Michelle A. Lawson, Matthew Macauley, David J. Elliott, Christian Büll, Emma Scott, Thomas J. Boltje, Richard R. Drake, Ning Wang, Jennifer Munkley
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105163- (2024)
Summary: Background: Bone metastasis is a common consequence of advanced prostate cancer. Bisphosphonates can be used to manage symptoms, but there are currently no curative treatments available. Altered tumour cell glycosylation is a hallmark of can
Externí odkaz:
https://doaj.org/article/afcff439ec0a4487aa2daaa9f610248c
Publikováno v:
LaTeCH@NAACL-HLT
Classification of texts by genre is an important application of natural language processing to literary corpora but remains understudied for premodern and non-English traditions. We develop a stylometric feature set for ancient Greek that enables ide
Publikováno v:
EMNLP/IJCNLP (3)
Computational stylometry has become an increasingly important aspect of literary criticism, but many humanists lack the technical expertise or language-specific NLP resources required to exploit computational methods. We demonstrate a stylometry tool
Autor:
Pramit Chaudhuri, Thomas J. Bolt
Publikováno v:
Classical World. 110:586-588
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102330- (2023)
Summary: Mammalian glycans show a diversity in sialic acid capping, constituting the sialome. Sialic acids can be extensively modified chemically, yielding sialic acid mimetics (SAMs). Here, we present a protocol for detecting and quantifying incorpo
Externí odkaz:
https://doaj.org/article/074db49a62954882ac17b7f57998b3fe
Autor:
Daniel Madriz Sørensen, Christian Büll, Thomas D. Madsen, Erandi Lira-Navarrete, Thomas Mandel Clausen, Alex E. Clark, Aaron F. Garretson, Richard Karlsson, Johan F. A. Pijnenborg, Xin Yin, Rebecca L. Miller, Sumit K. Chanda, Thomas J. Boltje, Katrine T. Schjoldager, Sergey Y. Vakhrushev, Adnan Halim, Jeffrey D. Esko, Aaron F. Carlin, Ramon Hurtado-Guerrero, Roberto Weigert, Henrik Clausen, Yoshiki Narimatsu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, the authors discover small molecules that inhibit glycosylation processes that occur in the Golgi apparatus of cells. The molecules reversibly inhibit formation of elaborate glycan structures without affecting secretion of glycoproteins.
Externí odkaz:
https://doaj.org/article/6c4688dc07fc45e1bcff09858f02a146
Autor:
Jona Merx, Jordi C. J. Hintzen, Giordano Proietti, Hidde Elferink, Yali Wang, Miriam R. B. Porzberg, Daan Sondag, Nurgül Bilgin, Jin Park, Jasmin Mecinović, Thomas J. Boltje
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttranslational modifications (PTMs) on histone tails regulate eukaryotic gene expression by impacting the chromatin structure and by modulating interactions with other cellular proteins. One such PTM has been identified as serine and thre
Externí odkaz:
https://doaj.org/article/d417fc4ccbb649dca6141ab06c89fcda
Autor:
Jona Merx, Rianne E. van Outersterp, Udo F. H. Engelke, Veronique Hendriks, Ron A. Wevers, Marleen C. D. G. Huigen, Huub W. A. H. Waterval, Irene M. L. W. Körver-Keularts, Jasmin Mecinović, Floris P. J. T. Rutjes, Jos Oomens, Karlien L. M. Coene, Jonathan Martens, Thomas J. Boltje
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
Combined metabolomics, NMR, and, IRIS identify biomarkers of hyperprolinemia type II (HPII) distinct from HPI and similar metabolic signatures as in patients with pyridoxine-dependent epilepsy.
Externí odkaz:
https://doaj.org/article/1073313437ec4eb190f04bb0c6441ddf