Zobrazeno 1 - 10 of 220 pro vyhledávání: '"Thomas J. Rogers"'
1
Akademický článek
Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4+ Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome
Autor: Ying Shao, William Cornwell, Keman Xu, Aaron Kirchhoff, Fatma Saasoud, Yifan Lu, Xiaohua Jiang, Gerard J. Criner, Hong Wang, Thomas J. Rogers, Xiaofeng Yang
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
There is a high incidence of tobacco use among intravenous opioid drug users. It is well established that opioids and tobacco smoke induce a degree of immune activation, and recent work suggests that the combination of these drugs promotes further ac
Externí odkaz: https://doaj.org/article/723840f998084308842d8dcdd0475540
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2
Akademický článek
Editorial: The Role of Opioid Receptors in Immune System Function
Autor: Thomas J. Rogers, Sabita Roy
Publikováno v: Frontiers in Immunology, Vol 12 (2022)
Externí odkaz: https://doaj.org/article/96ee6a01c3f946f98526700f6afda224
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3
Akademický článek
Cigarette Smoke and Morphine Promote Treg Plasticity to Th17 via Enhancing Trained Immunity
Autor: Ying Shao, Fatma Saaoud, William Cornwell, Keman Xu, Aaron Kirchhoff, Yifan Lu, Xiaohua Jiang, Hong Wang, Thomas J. Rogers, Xiaofeng Yang
Publikováno v: Cells, Vol 11, Iss 18, p 2810 (2022)
CD4+ regulatory T cells (Tregs) respond to environmental cues to permit or suppress inflammation, and atherosclerosis weakens Treg suppression and promotes plasticity. However, the effects of smoking plus morphine (SM + M) on Treg plasticity remain u
Externí odkaz: https://doaj.org/article/08de9576a3044008a513e2b839b84a76
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5
Akademický článek
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis
Autor: Hangfei Fu, Yu Sun, Ying Shao, Jason Saredy, Ramon Cueto, Lu Liu, Charles Drummer, Candice Johnson, Keman Xu, Yifan Lu, Xinyuan Li, Shu Meng, Eric R. Xue, Judy Tan, Nirag C. Jhala, Daohai Yu, Yan Zhou, Kayla J. Bayless, Jun Yu, Thomas J. Rogers, Wenhui Hu, Nathaniel W. Snyder, Jianxin Sun, Xuebin Qin, Xiaohua Jiang, Hong Wang, Xiaofeng Yang
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Interleukin (IL) 35 is a novel immunosuppressive heterodimeric cytokine in IL-12 family. Whether and how IL-35 regulates ischemia-induced angiogenesis in peripheral artery diseases are unrevealed. To fill this important knowledge gap, we used loss-of
Externí odkaz: https://doaj.org/article/df5786bc9d924b9887e995d716859508
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6
Akademický článek
Bidirectional Regulation of Opioid and Chemokine Function
Autor: Thomas J. Rogers
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
The opioid family of GPCRs consists of the classical opioid receptors, designated μ-, κ-, and δ-opioid receptors, and the orphanin-FQ receptor, and these proteins are expressed on both neuronal and hematopoietic cells. A number of laboratories hav
Externí odkaz: https://doaj.org/article/2936bc9b1f30408dbebd69ec2fbcabfe
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7
Akademický článek
Activation and polarization of circulating monocytes in severe chronic obstructive pulmonary disease
Autor: William D. Cornwell, Victor Kim, Xiaoxuan Fan, Marie Elena Vega, Frederick V. Ramsey, Gerard J. Criner, Thomas J. Rogers
Publikováno v: BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The ability of circulating monocytes to develop into lung macrophages and promote lung tissue damage depends upon their phenotypic pattern of differentiation and activation. Whether this phenotypic pattern varies with COPD severit
Externí odkaz: https://doaj.org/article/fbab8dbcf57d4cc8937cbaad52fa5373
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8
Akademický článek
Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers
Autor: Mark O. Aksoy, Victor Kim, William D. Cornwell, Thomas J. Rogers, Beata Kosmider, Karim Bahmed, Carlos Barrero, Salim Merali, Neena Shetty, Steven G. Kelsen
Publikováno v: Respiratory Research, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Identification of biomarkers of cigarette smoke –induced lung damage and early COPD is an area of intense interest. Glucose regulated protein of 78 kD (i.e., GRP78), a multi-functional protein which mediates cell responses to ox
Externí odkaz: https://doaj.org/article/9661c7fac6544bb69122ed0b711aaa9a
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9
Akademický článek
miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation
Autor: Silvia Moimas, Francesco Salton, Beata Kosmider, Nadja Ring, Maria C. Volpe, Karim Bahmed, Luca Braga, Michael Rehman, Simone Vodret, Maria Laura Graziani, Marla R. Wolfson, Nathaniel Marchetti, Thomas J. Rogers, Mauro Giacca, Gerard J. Criner, Serena Zacchigna, Marco Confalonieri
Publikováno v: ERJ Open Research, Vol 5, Iss 4 (2019)
Rationale Alveolar type II (ATII) cells act as adult stem cells contributing to alveolar type I (ATI) cell renewal and play a major role in idiopathic pulmonary fibrosis (IPF), as supported by familial cases harbouring mutations in genes specifically
Externí odkaz: https://doaj.org/article/fba4b51b7b0f4a85849633d5945cca83
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