Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Thomas J. Gonda"'
Autor:
Mahmoud A. Bassal, Saumya E. Samaraweera, Kelly Lim, Brooks A. Bernard, Sheree Bailey, Satinder Kaur, Paul Leo, John Toubia, Chloe Thompson-Peach, Tran Nguyen, Kyaw Ze Ya Maung, Debora A. Casolari, Diana G. Iarossi, Ilaria S. Pagani, Jason Powell, Stuart Pitson, Siria Natera, Ute Roessner, Ian D. Lewis, Anna L. Brown, Daniel G. Tenen, Nirmal Robinson, David M. Ross, Ravindra Majeti, Thomas J. Gonda, Daniel Thomas, Richard J. D’Andrea
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mitochondrial metabolism has been associated with tumourigenesis in acute myeloid leukaemia (AML) and currently considered as a potential therapeutic target. Here, the authors show, in patients with AML, that germline mutations in mitochondrial compl
Externí odkaz:
https://doaj.org/article/80997f20894a4c6ab09d4081863d91de
Autor:
Mahmoud A. Bassal, Saumya E. Samaraweera, Kelly Lim, Brooks A. Benard, Sheree Bailey, Satinder Kaur, Paul Leo, John Toubia, Chloe Thompson-Peach, Tran Nguyen, Kyaw Ze Ya Maung, Debora A. Casolari, Diana G. Iarossi, Ilaria S. Pagani, Jason Powell, Stuart Pitson, Siria Natera, Ute Roessner, Ian D. Lewis, Anna L. Brown, Daniel G. Tenen, Nirmal Robinson, David M. Ross, Ravindra Majeti, Thomas J. Gonda, Daniel Thomas, Richard J. D’Andrea
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/358e6495258e4f5ea0b4793e347e5337
Autor:
Nigel A.J. McMillan, Thomas J. Gonda, H. Peter Soyer, Dubravka Skalamera, Paul Leo, Graham Leggatt, Sara McKee, Melinda Christensen, Karin Sedelies, Madison Kelly, Daniel Clarke, Sora Fallaha, Mushfiq Shaikh, Melanie Murrell, Weili Wang, Alexander J. Stevenson, Zay Yar Oo, Max V. Ranall, Fawzi Bokhari, Brian Gabrielli
Contains siRNA primary screen analysis and subsequent supplemental analyses; Figure S1 Analysis was performed using customized R scripts and proceeded via a three step process; Figure S2 Summary of Z scores of the top 54 selected target hits from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78144266b989ba518e162f4a8b1a4ba4
https://doi.org/10.1158/1535-7163.22504167.v1
https://doi.org/10.1158/1535-7163.22504167.v1
Autor:
Nigel A.J. McMillan, Thomas J. Gonda, H. Peter Soyer, Dubravka Skalamera, Paul Leo, Graham Leggatt, Sara McKee, Melinda Christensen, Karin Sedelies, Madison Kelly, Daniel Clarke, Sora Fallaha, Mushfiq Shaikh, Melanie Murrell, Weili Wang, Alexander J. Stevenson, Zay Yar Oo, Max V. Ranall, Fawzi Bokhari, Brian Gabrielli
Primary screening daat from kinome siRNA screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3523c6b3db870df92bcd5ab67a801432
https://doi.org/10.1158/1535-7163.22504164.v1
https://doi.org/10.1158/1535-7163.22504164.v1
Autor:
Nigel A.J. McMillan, Thomas J. Gonda, H. Peter Soyer, Dubravka Skalamera, Paul Leo, Graham Leggatt, Sara McKee, Melinda Christensen, Karin Sedelies, Madison Kelly, Daniel Clarke, Sora Fallaha, Mushfiq Shaikh, Melanie Murrell, Weili Wang, Alexander J. Stevenson, Zay Yar Oo, Max V. Ranall, Fawzi Bokhari, Brian Gabrielli
Human papillomavirus (HPV) is the causative agent in cervical cancer. HPV oncogenes are major drivers of the transformed phenotype, and the cancers remain addicted to these oncogenes. A screen of the human kinome has identified inhibition of Aurora k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35b51575ed57089fdf4e66e7e535781
https://doi.org/10.1158/1535-7163.c.6537636
https://doi.org/10.1158/1535-7163.c.6537636
Autor:
Nigel A.J. McMillan, Thomas J. Gonda, H. Peter Soyer, Dubravka Skalamera, Paul Leo, Graham Leggatt, Sara McKee, Melinda Christensen, Karin Sedelies, Madison Kelly, Daniel Clarke, Sora Fallaha, Mushfiq Shaikh, Melanie Murrell, Weili Wang, Alexander J. Stevenson, Zay Yar Oo, Max V. Ranall, Fawzi Bokhari, Brian Gabrielli
SiRNA screening data validated gene lists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083777a1c2ce8605abacf74ccec52e5f
https://doi.org/10.1158/1535-7163.22504161.v1
https://doi.org/10.1158/1535-7163.22504161.v1
Autor:
Robert G. Ramsay, Robin L. Anderson, Thomas J. Gonda, Jordane Malaterre, Lloyd Pereira, Sandra Carpinteri, Dane Cheasley, Ryan Stanley Cross, Yvette Drabsch, Rebecca Yu Miao
MYB oncogene upregulation is associated with estrogen receptor (ER)-positive breast cancer, but disease requirements for MYB function in vivo have not been explored. In this study, we provide evidence of a critical requirement for MYB functions in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::627a9baf288c0fc7db5d12382d29eebc
https://doi.org/10.1158/0008-5472.c.6503105.v1
https://doi.org/10.1158/0008-5472.c.6503105.v1
Autor:
Robert G. Ramsay, Robin L. Anderson, Thomas J. Gonda, Jordane Malaterre, Lloyd Pereira, Sandra Carpinteri, Dane Cheasley, Ryan Stanley Cross, Yvette Drabsch, Rebecca Yu Miao
PDF file - 89K, Epithelial cell gene expression in tissues employed for the analysis of MYB and A-MYB expression in mammary glands at different stages of development contain epithelial cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7462a43974131a713d7a90c4af138a68
https://doi.org/10.1158/0008-5472.22390934.v1
https://doi.org/10.1158/0008-5472.22390934.v1
Autor:
Robert G. Ramsay, Robin L. Anderson, Thomas J. Gonda, Jordane Malaterre, Lloyd Pereira, Sandra Carpinteri, Dane Cheasley, Ryan Stanley Cross, Yvette Drabsch, Rebecca Yu Miao
PDF file - 360K, Transgene expression driven by the MMTV promoter is not effected by the loss of MYB in the mammary gland.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8a688df5e79cbd760c170f9a059bf7
https://doi.org/10.1158/0008-5472.22390937.v1
https://doi.org/10.1158/0008-5472.22390937.v1
Autor:
Robert G. Ramsay, Robin L. Anderson, Thomas J. Gonda, Jordane Malaterre, Lloyd Pereira, Sandra Carpinteri, Dane Cheasley, Ryan Stanley Cross, Yvette Drabsch, Rebecca Yu Miao
PDF file - 168K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a4ca8455525d7f645e771448e5c0bb
https://doi.org/10.1158/0008-5472.22390928
https://doi.org/10.1158/0008-5472.22390928