Identification of traits and functional connectivity-based neurotraits of chronic pain.

Autor: Etienne Vachon-Presseau, Sara E Berger, Taha B Abdullah, James W Griffith, Thomas J Schnitzer, A Vania Apkarian

Publikováno v: PLoS Biology, Vol 17, Iss 8, p e3000349 (2019)

Psychological and personality factors, socioeconomic status, and brain properties all contribute to chronic pain but have essentially been studied independently. Here, we administered a broad battery of questionnaires to patients with chronic back pa

Externí odkaz: https://doaj.org/article/ab3ebe3e42a94f7a9c841af28a6047ae

Effect size varies based on calculation method and may affect interpretation of treatment effect: an illustration using randomised clinical trials in osteoarthritis

Autor: Thomas J. Schnitzer, Philip G. Conaghan, Francis Berenbaum, Lucy Abraham, Joseph C. Cappelleri, Andrew G. Bushmakin, Lars Viktrup, Ruoyong Yang, Mark T. Brown

Publikováno v: Advances in Rheumatology, Vol 64, Iss 1, Pp 1-5 (2024)

Abstract Background To illustrate how (standardised) effect sizes (ES) vary based on calculation method and to provide considerations for improved reporting. Methods Data from three trials of tanezumab in subjects with osteoarthritis were analyzed. E

Externí odkaz: https://doaj.org/article/f628c39303c84570a9c6556e1bdaf14a

Does sex affect the efficacy of systemic pharmacological treatments of pain in knee osteoarthritis? A systematic review

Autor: Santiago Espinosa-Salas, Leila Bagherzadeh, Q. Eileen Wafford, Graeme Witte, Thomas J. Schnitzer

Publikováno v: Osteoarthritis and Cartilage Open, Vol 6, Iss 1, Pp 100438- (2024)

Objective: To determine whether sex influences the analgesic efficacy of systemic pharmacological treatment in patients with knee osteoarthritis. Design: A systematic review, guided by Cochrane methods, sourced studies from Medline, Cochrane Library,

Externí odkaz: https://doaj.org/article/64837221333341d8a9423689cef393e0

Opioids for Osteoarthritis: Cross-Sectional Survey of Patient Perspectives and Satisfaction

Autor: Thomas J. Schnitzer, Rebecca L. Robinson, Lars Viktrup, Joseph C. Cappelleri, Andrew G. Bushmakin, Leslie Tive, Mia Berry, Chloe Walker, James Jackson

Publikováno v: Journal of Clinical Medicine; Volume 12; Issue 7; Pages: 2733

Patients often take opioids to relieve osteoarthritis (OA) pain despite limited benefits and potential harms. This study aimed to compare cross-sectional perspectives of patients that were taking prescription opioid (N = 471) or nonopioid medications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a4371733e102b600fcbd7cb49a9c62

Single and Composite Endpoints of Within-Patient Improvement in Symptoms: Pooled Tanezumab Data in Patients with Osteoarthritis

Autor: Francis Berenbaum, Isabelle Davignon, Christine R. West, Robert H. Dworkin, Thomas J. Schnitzer, Philip G. Conaghan, Davide Gatti, Lars Viktrup, Kenneth M. Verburg, Ruoyong Yang

Publikováno v: Rheumatology and Therapy
Rheumatology and Therapy, 2021, ⟨10.1007/s40744-021-00372-2⟩
Rheumatology and Therapy, Springer, 2021, ⟨10.1007/s40744-021-00372-2⟩

Introduction: Combining measures of key core domains (especially pain and function) into a composite endpoint that requires each patient to meet a threshold of improvement for each domain provides information on multiple aspects of osteoarthritis wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3128ddfd539e0978166e5e2750885d4
https://doi.org/10.1007/s40744-021-00372-2