Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thomas J Rea"'
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29889 (2012)
In this paper, we use a statistical estimator developed in astrophysics to study the distribution and organization of features of the human genome. Using the human reference sequence we quantify the global distribution of CpG islands (CGI) in each ch
Externí odkaz:
https://doaj.org/article/127ad1ec073047d6a3a76dde6f0132b8
Autor:
Charles L. Bisgaier, Arnold D. Essenburg, Blake C. Barnett, Bruce J. Auerbach, Sabine Haubenwallner, Todd Leff, Andrew D. White, Paul Creger, Michael E. Pape, Thomas J. Rea, Roger S. Newton
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 1, Pp 17-30 (1998)
In the current studies we describe the effects of PD 72953 and related compounds on lipoprotein levels in chowfed male rats. After 2 weeks, 10 mg/kg of PD 72953 daily was as effective as 100 mg/kg gemfibrozil for elevating HDL-cholesterol. At 100 mg/
Externí odkaz:
https://doaj.org/article/c311ea301bc5471db5bad401d9635744
Publikováno v:
Pharmacological Research. 111:86-99
Epidemiological studies support an inverse correlation between HDL-C and cardiovascular disease. However, low HDL-C levels do not always segregate with premature disease. These include, LCAT deficiency and the apolipoproteinA-IMilano (AIM) variant. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a628ef7b6d6dbe4fa61169c00d8473
https://doi.org/10.1016/j.phrs.2016.05.001
https://doi.org/10.1016/j.phrs.2016.05.001
Autor:
Kirstin D. Mazany, M E Pape, Kevin Jon Williams, C L Bisgaier, Thomas J. Rea, A. D. Essenburg, Wendi V. Rodrigueza
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:2132-2139
Abstract Phospholipid liposomes are synthetic mediators of “reverse” cholesterol transport from peripheral tissue to liver in vivo and can shrink atherosclerotic lesions in animals. Hepatic disposal of this cholesterol, however, has not been exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facbdb83cf216a07ec3ae8bd6815474d
https://doi.org/10.1161/01.atv.17.10.2132
https://doi.org/10.1161/01.atv.17.10.2132
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 1, p e29889 (2012)
PLoS ONE, Vol 7, Iss 1, p e29889 (2012)
In this paper, we use a statistical estimator developed in astrophysics to study the distribution and organization of features of the human genome. Using the human reference sequence we quantify the global distribution of CpG islands (CGI) in each ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397c973128a32d12e2b38d68c1c63024
http://europepmc.org/articles/PMC3256200
http://europepmc.org/articles/PMC3256200
Autor:
Thomas J. Rea, Paul S. Kaytes, Gabriel Vogeli, Arthur P. Bertolino, Allen E. Buhl, Alistair R. McNab, Nicole T. Hatzenbuhler, Thomas T. Kawabe, Vince Groppi
Publikováno v:
Journal of Investigative Dermatology. 97:835-842
A genomic clone for a member of the mouse type I hair keratin protein family has been isolated and analyzed in order to study the regulation of this keratin during the hair growth cycle. The coding sequence is divided into seven exons. The gene struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16bfe6278fc521283a1ad986a6720fe
https://doi.org/10.1111/1523-1747.ep12491511
https://doi.org/10.1111/1523-1747.ep12491511
Autor:
Vince Groppi, Gabriel Vogeli, Daniel J. Waldon, Thomas J. Rea, Paula Andrus, Thomas E. Wagner, Allen E. Buhl, Alistair R. McNab, Thomas K. Kawabe
Publikováno v:
Proceedings of the National Academy of Sciences. 87:6848-6852
We have generated a transgenic mouse line by microinjection of a chimeric DNA fragment (KER-CAT) containing a hair-specific, murine ultra-high-sulfur keratin promoter (KER) fused to the coding region of the bacterial chloramphenicol acetyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b90d3bcf7d00c3db618a61acaac38bc
https://doi.org/10.1073/pnas.87.17.6848
https://doi.org/10.1073/pnas.87.17.6848
Publikováno v:
Perspectives in biology and medicine. 49(4)
Despite remarkable advances in diagnosis and therapy, ischemic heart disease (IHD) remains a leading cause of morbidity and mortality in industrialized countries. Recent efforts to estimate the influence of genetic variation on IHD risk have focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8107edf1dde38ef2b2125a710f49aa4f
https://pubmed.ncbi.nlm.nih.gov/17146134
https://pubmed.ncbi.nlm.nih.gov/17146134
Autor:
Sara C. Hamon, Myriam Fornage, Thomas J. Rea, Eric Boerwinkle, Charles F. Sing, Andrew G. Clark, James E. Hixson, Kathy L.E. Klos
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 26(8)
Objective— To identify common variations in genes in the reverse cholesterol transport pathway with nongender-specific influence on plasma lipid and apolipoprotein levels. Methods and Results— An average of 5 single nucleotide polymorphisms (SNPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98136fa742a151e81902517e8f11320
https://pubmed.ncbi.nlm.nih.gov/16763159
https://pubmed.ncbi.nlm.nih.gov/16763159
Autor:
Sara C. Hamon, Charles F. Sing, C. M. Brown, Eric Boerwinkle, Thomas J. Rea, Andrew G. Clark, James E. Hixson
Apolipoproteins (apo) A-I and C-III are components of high-density lipoprotein-cholesterol (HDL-C), a quantitative trait negatively correlated with risk of cardiovascular disease (CVD). We analyzed the contribution of individual and pairwise combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f881d5dc5f0b5e6902e2e981fbab38
https://europepmc.org/articles/PMC1698872/
https://europepmc.org/articles/PMC1698872/
