Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Thomas J Owen"'
Autor:
Richard J. Jabbour, Thomas J. Owen, Pragati Pandey, Marina Reinsch, Brian Wang, Oisín King, Liam Steven Couch, Dafni Pantou, David S. Pitcher, Rasheda A. Chowdhury, Fotios G. Pitoulis, Balvinder S. Handa, Worrapong Kit-Anan, Filippo Perbellini, Rachel C. Myles, Daniel J. Stuckey, Michael Dunne, Mayooran Shanmuganathan, Nicholas S. Peters, Fu Siong Ng, Florian Weinberger, Cesare M. Terracciano, Godfrey L. Smith, Thomas Eschenhagen, Sian E. Harding
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix, may be a novel therapy for heart failure. EHTs restore cardiac function in rodent injury models, but more data are needed in clinically relevant settings. Accordin
Externí odkaz:
https://doaj.org/article/5f7e39207cc8495596ab20ad1eee6e60
Autor:
Qasim A. Majid, Annabelle T. R. Fricker, David A. Gregory, Natalia Davidenko, Olivia Hernandez Cruz, Richard J. Jabbour, Thomas J. Owen, Pooja Basnett, Barbara Lukasiewicz, Molly Stevens, Serena Best, Ruth Cameron, Sanjay Sinha, Sian E. Harding, Ipsita Roy
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Cardiovascular diseases (CVD) constitute a major fraction of the current major global diseases and lead to about 30% of the deaths, i.e., 17.9 million deaths per year. CVD include coronary artery disease (CAD), myocardial infarction (MI), arrhythmias
Externí odkaz:
https://doaj.org/article/8b3f79ae35c44aadac930a8f455de3e1
Autor:
Thomas J. Owen, Sian E. Harding
Publikováno v:
Journal of Muscle Research and Cell Motility
Tissue engineering is a complex field where the elements of biology and engineering are combined in an attempt to recapitulate the native environment of the body. Tissue engineering has shown one thing categorically; that the human body is extremely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3234052c3fbdb39375ae1f65dfa5677
https://doi.org/10.1007/s10974-019-09528-8
https://doi.org/10.1007/s10974-019-09528-8
Autor:
Rasheda A. Chowdhury, Marina Reinsch, Godfrey L. Smith, Dafni Pantou, Mayooran Shanmuganathan, Florian Weinberger, Fu Siong Ng, Thomas Eschenhagen, Liam Couch, Thomas J. Owen, Oisín King, Cesare M. Terracciano, David S. Pitcher, Daniel J. Stuckey, Nicholas S. Peters, Balvinder S. Handa, Richard J. Jabbour, Brian Wang, Pragati Pandey, Michael Dunne, Rachel C. Myles, Worrapong Kit-Anan, Filippo Perbellini, Fotios G. Pitoulis, Sian E. Harding
Publikováno v:
JCI Insight
Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix, may be a novel therapy for heart failure. EHTs restore cardiac function in rodent injury models, but more data are needed in clinically relevant settings. Accordin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f4fe1a459529be1768d0d3158bd657
http://hdl.handle.net/10044/1/90648
http://hdl.handle.net/10044/1/90648
Autor:
Richard J. Jabbour, Florian Weinberger, Thomas J. Owen, Godfrey L. Smith, Thomas Eschenhagen, Sian E. Harding, Marina Reinsch, Pragati Pandey
Publikováno v:
Young Investigators Award.
Introduction Engineered heart tissue (EHT) strategies, by combining cells within a hydrogel matrix may overcome the limitations of intracoronary/myocardial cell delivery routes. EHTs regenerate heart muscle in small animal models but data regarding c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9057e3aaddad454def194d97ea6cb281
https://doi.org/10.1136/heartjnl-2020-bcs.137
https://doi.org/10.1136/heartjnl-2020-bcs.137
Future potential of engineered heart tissue patches for repairing the damage caused by heart attacks
Publikováno v:
Expert Review of Medical Devices. 17:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4af77f244df9813000ae2dbfcc967fb
https://doi.org/10.1080/17434440.2020.1700793
https://doi.org/10.1080/17434440.2020.1700793
Autor:
Marina Reinsch, Thomas J. Owen, Florian Weinberger, Pragati Pandey, Richard J. Jabbour, T Eschenghagen, Cesare M. Terracciano, Godfrey L. Smith, O King, Fu Siong Ng, Mayooran Shanmuganathan, Alexander R. Lyon, Sian E. Harding, Brian Wang, Daniel J. Stuckey
Publikováno v:
European Heart Journal. 40
Introduction The lack of efficacy of stem cell therapy for the treatment of heart failure may be related to the poor retention rates offered by existing delivery methods (intra-coronary/ intramyocardial). Tissue engineering strategies improve cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46611efb261c61d43562d115af886817
https://doi.org/10.1093/eurheartj/ehz746.0345
https://doi.org/10.1093/eurheartj/ehz746.0345
Autor:
Cesare M. Terracciano, Pragati Pandey, Florian Weinberger, Thomas J. Owen, Marina Reinsch, Richard J. Jabbour, Sian E. Harding, Thomas Eschenhagen
Publikováno v:
Basic Science.
Introduction The lack of efficacy of stem cell therapy for the treatment of heart failure may be related to the poor retention rates offered by existing delivery methods (intra-coronary/intramyocardial). Tissue engineering strategies improve cell ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b7278a0cb77c1bb7fe56584b2dd8ee
https://doi.org/10.1136/heartjnl-2019-bcs.190
https://doi.org/10.1136/heartjnl-2019-bcs.190
Autor:
Katja Gehmlich, Saheed Lawal, Kenneth T. MacLeod, Steven B. Marston, Christina Rowlands, Ross Wilkinson, Thomas J. Owen, Anita Alvarez-Laviada, Shuangyi Cao, Hsiang-Yu Yang, Weihua Song, Samata S. Pandey
Publikováno v:
H1226
H1213
H1213
Patients with hypertrophic cardiomyopathy, particularly young adults, can die from arrhythmia, but the mechanism underlying abnormal rhythm formation remains unknown. C57Bl6 × CBA/Ca mice carrying a cardiac actin ( ACTC) E99K (Glu99Lys) mutation rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eef6e1aa6ac78c8d5437486fce922c2
https://ora.ox.ac.uk/objects/uuid:7df5d34a-c448-4b91-9442-f109db767609
https://ora.ox.ac.uk/objects/uuid:7df5d34a-c448-4b91-9442-f109db767609
Autor:
Robert Valentine, John R. Arrand, Kathryn L Date, Marilyn B. Chukwuma, Victoria H. J. Wood, Christopher W. Dawson, Lawrence S. Young, Thomas J Owen, John D. O'Neil
Publikováno v:
Journal of General Virology. 89:2833-2842
The Epstein–Barr virus (EBV)-encoded EBNA1 protein is expressed in all virus-associated tumours, including nasopharyngeal carcinoma (NPC), where it plays an essential role in EBV genome maintenance, replication and transcription. Previous studies s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1a10b4f84c59123c6adb60cf237142
https://doi.org/10.1099/vir.0.2008/003392-0
https://doi.org/10.1099/vir.0.2008/003392-0