Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Thomas J O'Dell"'
Autor:
Dawn H Loh, Shekib A Jami, Richard E Flores, Danny Truong, Cristina A Ghiani, Thomas J O’Dell, Christopher S Colwell
Publikováno v:
eLife, Vol 4 (2015)
Robust sleep/wake rhythms are important for health and cognitive function. Unfortunately, many people are living in an environment where their circadian system is challenged by inappropriate meal- or work-times. Here we scheduled food access to the s
Externí odkaz:
https://doaj.org/article/ad17da89a3c8406593f3e7c8620dbd30
Autor:
Brian J Wiltgen, Gordon A Royle, Erin E Gray, Andrea Abdipranoto, Nopporn Thangthaeng, Nate Jacobs, Faysal Saab, Susumu Tonegawa, Stephen F Heinemann, Thomas J O'Dell, Michael S Fanselow, Bryce Vissel
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
A central concept in the field of learning and memory is that NMDARs are essential for synaptic plasticity and memory formation. Surprisingly then, multiple studies have found that behavioral experience can reduce or eliminate the contribution of the
Externí odkaz:
https://doaj.org/article/070d953a46ae4bb5a7187a01a6fc26ce
Autor:
Louisa M-C Wang, Joanna M Dragich, Takashi Kudo, Irene H Odom, David K Welsh, Thomas J O'Dell, Christopher S Colwell
Publikováno v:
ASN Neuro, Vol 1 (2009)
Genes responsible for generating circadian oscillations are expressed in a variety of brain regions not typically associated with circadian timing. The functions of this clock gene expression are largely unknown, and in the present study we sought to
Externí odkaz:
https://doaj.org/article/cdd3cb436b76466db19aaca56504f17c
Autor:
Shekib A. Jami, Brent J. Wilkinson, Ryan Guglietta, Nicolas Hartel, Walter E. Babiec, Nicholas A. Graham, Marcelo P. Coba, Thomas J. O’Dell
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Activation of β-adrenergic receptors (β-ARs) not only enhances learning and memory but also facilitates the induction of long-term potentiation (LTP), a form of synaptic plasticity involved in memory formation. To identify the mechanisms u
Externí odkaz:
https://doaj.org/article/aa4d84c0487549968fd5225fa6d87caf
Publikováno v:
The Journal of Neuroscience
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 29
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 40, iss 29
The anterior cingulate cortex (ACC) is implicated in effort exertion and choices based on effort cost, but it is still unclear how it mediates this cost-benefit evaluation. Here, male rats were trained to exert effort for a high-value reward (sucrose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcab035972dfd569ffc0b866801ae50
http://europepmc.org/articles/PMC7363467
http://europepmc.org/articles/PMC7363467
Autor:
Edita Bulovaite, Zhen Qiu, Maximilian Kratschke, Adrianna Zgraj, David G. Fricker, Eleanor J. Tuck, Ragini Gokhale, Babis Koniaris, Shekib A. Jami, Paula Merino-Serrais, Elodie Husi, Lorena Mendive-Tapia, Marc Vendrell, Thomas J. O’Dell, Javier DeFelipe, Noboru H. Komiyama, Anthony Holtmaat, Erik Fransén, Seth G.N. Grant
Publikováno v:
Neuron
Bulovaite, E, Qiu, Z, Kratschke, M, Zgraj, A, Fricker, D G, Tuck, E J, Gokhale, R, Koniaris, B, Jami, S A, Merino-Serrais, P, Husi, E, Mendive-Tapia, L, Vendrell, M, O'Dell, T J, DeFelipe, J, Komiyama, N H, Holtmaat, A, Fransén, E & Grant, S G N 2022, ' A brain atlas of synapse protein lifetime across the mouse lifespan ', Neuron . https://doi.org/10.1016/j.neuron.2022.09.009
Bulovaite, E, Qiu, Z, Kratschke, M, Zgraj, A, Fricker, D G, Tuck, E J, Gokhale, R, Koniaris, B, Jami, S A, Merino-Serrais, P, Husi, E, Mendive-Tapia, L, Vendrell, M, O'Dell, T J, DeFelipe, J, Komiyama, N H, Holtmaat, A, Fransén, E & Grant, S G N 2022, ' A brain atlas of synapse protein lifetime across the mouse lifespan ', Neuron . https://doi.org/10.1016/j.neuron.2022.09.009
The lifetime of proteins in synapses is important for their signaling, maintenance, and remodeling, and for memory duration. We quantified the lifetime of endogenous PSD95, an abundant postsynaptic protein in excitatory synapses, at single-synapse re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ab62ef318976a1b25f15c5b508a7f7
http://hdl.handle.net/10261/305259
http://hdl.handle.net/10261/305259
Autor:
Thomas J. O'Dell
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 13
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 13
Although Hebbian LTP has an important role in memory formation, the properties of Hebbian LTP cannot fully account for, and in some cases seem incompatible with, fundamental properties of associative learning. Importantly, findings from computational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8839a489fddbddafabffcaab3ad72199
https://pubmed.ncbi.nlm.nih.gov/35135856
https://pubmed.ncbi.nlm.nih.gov/35135856
Autor:
Walter E. Babiec, Thomas J. O'Dell
Publikováno v:
Journal of Neurophysiology. 119:597-607
Although long thought to simply be a source of synaptic noise, spontaneous, action potential-independent release of neurotransmitter from presynaptic terminals has multiple roles in synaptic function. We explored whether and to what extent the two pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::812d9c28e48735c2562a643ffbe4ddb0
https://doi.org/10.1152/jn.00628.2017
https://doi.org/10.1152/jn.00628.2017
Autor:
Alexandra Stolyarova, Mohsen Rakhshan, Alireza Soltani, Megan A. K. Peters, Evan E. Hart, Hakwan Lau, Thomas J. O'Dell, Alicia Izquierdo
It has been suggested the subjective sense of certainty, or confidence, in ambiguous sensory cues can alter the interpretation of reward feedback and facilitate learning. We trained rats to report the orientation of ambiguous visual stimuli according
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85215a4e3f644dc3f140a94af916042b
https://doi.org/10.1101/655860
https://doi.org/10.1101/655860
Cognitive impairment (CI), a debilitating and pervasive feature of multiple sclerosis (MS), is correlated with hippocampal atrophy. Findings from postmortem MS hippocampi indicate that expression of genes involved in both excitatory and inhibitory ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c31b6dbb6025b968a062f6909567e33
https://europepmc.org/articles/PMC6289277/
https://europepmc.org/articles/PMC6289277/