Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Thomas J Maresca"'
Autor:
Olga Afonso, Colleen M Castellani, Liam P Cheeseman, Jorge G Ferreira, Bernardo Orr, Luisa T Ferreira, James J Chambers, Eurico Morais-de-Sá, Thomas J Maresca, Helder Maiato
Publikováno v:
eLife, Vol 8 (2019)
According to the prevailing ‘clock’ model, chromosome decondensation and nuclear envelope reformation when cells exit mitosis are byproducts of Cdk1 inactivation at the metaphase-anaphase transition, controlled by the spindle assembly checkpoint.
Externí odkaz:
https://doaj.org/article/24106345d4c44c78b7ee34b3dc5eaca3
Autor:
Vikash Verma, Thomas J Maresca
Publikováno v:
eLife, Vol 8 (2019)
Microtubules (MTs) are essential for cleavage furrow positioning during cytokinesis, but the mechanisms by which MT-derived signals spatially define regions of cortical contractility are unresolved. In this study cytokinesis regulators visualized in
Externí odkaz:
https://doaj.org/article/a73ffb52cc9f40beb2e9aaec8261d2b0
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Chromosomes bind microtubules (MT) from opposite spindle poles and the generated tension stabilizes kinetochore-MT attachments. Here the authors measure kinetochore forces by engineering two force sensors and propose that kinetochore fibers exert hun
Externí odkaz:
https://doaj.org/article/65caf202ae7448c48eaf1423297ed30a
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 460-468 (2015)
Chromosome bi-orientation occurs after conversion of initial lateral attachments between kinetochores and spindle microtubules into stable end-on attachments near the cell equator. After bi-orientation, chromosomes experience tension from spindle for
Externí odkaz:
https://doaj.org/article/9ee6ebfe958c426cb308b15bed13ce18
Publikováno v:
Biology, Vol 8, Iss 3, p 55 (2019)
The primary goal of cytokinesis is to produce two daughter cells, each having a full set of chromosomes. To achieve this, cells assemble a dynamic structure between segregated sister chromatids called the contractile ring, which is made up of filamen
Externí odkaz:
https://doaj.org/article/e0ee5fbabe5e437d9034bb9766cd38a9
Autor:
Thomas J. Maresca, Margaux R Audett
Publikováno v:
Essays Biochem
The kinetochore (KT) field has matured tremendously since Earnshaw first identified CENP-A, CENP-B, and CENP-C [1,2]. In the past 35 years, the accumulation of knowledge has included: defining the parts list, identifying epistatic networks of interde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e3426f017f6f3e5df6af42917d9f62
https://doi.org/10.1042/ebc20190069
https://doi.org/10.1042/ebc20190069
Autor:
Vikash Verma, Thomas J. Maresca
Publikováno v:
Molecular Biology of the Cell. 33
Formation of a bipolar spindle is required for the faithful segregation of chromosomes during cell division. Twenty-five years ago, a transformative insight into how bipolarity is achieved was provided by Rebecca Heald, Eric Karsenti, and colleagues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6200868048fe034c67deb911365dff31
https://doi.org/10.1091/mbc.e21-08-0400
https://doi.org/10.1091/mbc.e21-08-0400
Autor:
Erin L Johnson, Thomas J. Maresca, Marcin R. Przewloka, Dylan M Barcelos, Evelin Oroszne Szalai, Margaux R Audett, Jessica M McGory
KNL1 is a large intrinsically disordered kinetochore (KT) protein that recruits spindle assembly checkpoint (SAC) components to mediate SAC signaling. The N-terminal region (NTR) of KNL1 possesses two activities that have been implicated in SAC silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6eceeb7775054c06a9900e36d1b09c8
https://eprints.soton.ac.uk/456542/
https://eprints.soton.ac.uk/456542/
Autor:
Margaux R, Audett, Erin L, Johnson, Jessica M, McGory, Dylan M, Barcelos, Evelin Oroszne, Szalai, Marcin R, Przewloka, Thomas J, Maresca
Publikováno v:
Molecular biology of the cell. 33(1)
KNL1 is a large intrinsically disordered kinetochore (KT) protein that recruits spindle assembly checkpoint (SAC) components to mediate SAC signaling. The N-terminal region (NTR) of KNL1 possesses two activities that have been implicated in SAC silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec2425438d69273d27801270f3950641
https://pubmed.ncbi.nlm.nih.gov/34705493
https://pubmed.ncbi.nlm.nih.gov/34705493
Publikováno v:
Journal of Biological Chemistry. 294:11876-11891
Ca2+ oscillations and consequent Ca2+/calmodulin-dependent protein kinase II (CaMKII) activation are required for embryogenesis, as well as neuronal, immunological, and cardiac signaling. Fertilization directly results in Ca2+ oscillations, but the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b85fc13b2fb3bbc494e163d4fa8e450
https://doi.org/10.1074/jbc.ra119.009235
https://doi.org/10.1074/jbc.ra119.009235