Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Thomas J J, Johnson"'
Autor:
Edwardo G. M. Reynolds, Thomas Lopdell, Yu Wang, Kathryn M. Tiplady, Chad S. Harland, Thomas J. J. Johnson, Catherine Neeley, Katie Carnie, Richard G. Sherlock, Christine Couldrey, Stephen R. Davis, Bevin L. Harris, Richard J. Spelman, Dorian J. Garrick, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 54, Iss 1, Pp 1-16 (2022)
Abstract Background Deleterious recessive conditions have been primarily studied in the context of Mendelian diseases. Recently, several deleterious recessive mutations with large effects were discovered via non-additive genome-wide association studi
Externí odkaz:
https://doaj.org/article/c6d74fe902814b03a9b570eab1034eda
Autor:
Tania Fink, Thomas J. Lopdell, Kathryn Tiplady, Renee Handley, Thomas J. J. Johnson, Richard J. Spelman, Stephen R. Davis, Russell G. Snell, Mathew D. Littlejohn
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background The DGAT1 gene encodes an enzyme responsible for catalysing the terminal reaction in mammary triglyceride synthesis, and underpins a well-known pleiotropic quantitative trait locus (QTL) with a large influence on milk composition
Externí odkaz:
https://doaj.org/article/c12b3a625ee1495d8ea1c2bf4fc75c90
Autor:
Swati Jivanji, Gemma Worth, Thomas J. Lopdell, Anna Yeates, Christine Couldrey, Edwardo Reynolds, Kathryn Tiplady, Lorna McNaughton, Thomas J. J. Johnson, Stephen R. Davis, Bevin Harris, Richard Spelman, Russell G. Snell, Dorian Garrick, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 51, Iss 1, Pp 1-18 (2019)
Abstract Background White spotting of the coat is a characteristic trait of various domestic species including cattle and other mammals. It is a hallmark of Holstein–Friesian cattle, and several previous studies have detected genetic loci with majo
Externí odkaz:
https://doaj.org/article/4182bd4389d749efa8e40b3f86fe123a
Autor:
Thomas J. Lopdell, Kathryn Tiplady, Christine Couldrey, Thomas J. J. Johnson, Michael Keehan, Stephen R. Davis, Bevin L. Harris, Richard J. Spelman, Russell G. Snell, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 51, Iss 1, Pp 1-16 (2019)
Abstract Background Over many years, artificial selection has substantially improved milk production by cows. However, the genes that underlie milk production quantitative trait loci (QTL) remain relatively poorly characterised. Here, we investigate
Externí odkaz:
https://doaj.org/article/9e66835c202f45f5869a32d75de44650
Autor:
Thomas J. Lopdell, Kathryn Tiplady, Maksim Struchalin, Thomas J. J. Johnson, Michael Keehan, Ric Sherlock, Christine Couldrey, Stephen R. Davis, Russell G. Snell, Richard J. Spelman, Mathew D. Littlejohn
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background Lactose provides an easily-digested energy source for neonates, and is the primary carbohydrate in milk in most species. Bovine lactose is also a key component of many human food products. However, compared to analyses of other mi
Externí odkaz:
https://doaj.org/article/75617e1ab9624235b3aa763ae9625896
Autor:
Edwardo G M, Reynolds, Catherine, Neeley, Thomas J, Lopdell, Michael, Keehan, Keren, Dittmer, Chad S, Harland, Christine, Couldrey, Thomas J J, Johnson, Kathryn, Tiplady, Gemma, Worth, Mark, Walker, Stephen R, Davis, Richard G, Sherlock, Katie, Carnie, Bevin L, Harris, Carole, Charlier, Michel, Georges, Richard J, Spelman, Dorian J, Garrick, Mathew D, Littlejohn
Publikováno v:
Nature genetics. 53(7)
Mammalian species carry ~100 loss-of-function variants per individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b98754a5d82802f41f89347a7d5cacda
https://pubmed.ncbi.nlm.nih.gov/34045765
https://pubmed.ncbi.nlm.nih.gov/34045765