Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients.

Autor: Anni A Winckelmann, Lærke V Munk-Petersen, Thomas A Rasmussen, Jesper Melchjorsen, Thomas J Hjelholt, David Montefiori, Lars Østergaard, Ole S Søgaard, Martin Tolstrup

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62074 (2013)

Toll-like receptor (TLR) agonists can reactivate HIV from latently infected cells in vitro. We aimed to investigate the TLR-9 agonist, CPG 7909's in vivo effect on the proviral HIV reservoir and HIV-specific immunity. This was a post-hoc analysis of

Externí odkaz: https://doaj.org/article/9b75dc2f05644169b9a48e953d9cb249

Development and validation of a model for predicting mortality in patients with hip fracture

Autor: Thomas J Hjelholt, Søren P Johnsen, Peter K Brynningsen, Jakob S Knudsen, Daniel Prieto-Alhambra, Alma B Pedersen

Publikováno v: Hjelholt, T J, Johnsen, S P, Brynningsen, P K, Knudsen, J S, Prieto-Alhambra, D & Pedersen, A B 2022, ' Development and validation of a model for predicting mortality in patients with hip fracture ', Age and Ageing, vol. 51, no. 1, afab233 . https://doi.org/10.1093/ageing/afab233

Objective to develop a user-friendly prediction tool of 1-year mortality for patients with hip fracture, in order to guide clinicians and patients on appropriate targeted preventive measures. Design population-based cohort study from 2011 to 2017 usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256573f5680213a871e8783b5ff47e1b
https://doi.org/10.1093/ageing/afab233

Association of CHA2 DS2 -VASc Score with Stroke, Thromboembolism, and Death in Hip Fracture Patients

Autor: Thomas J. Hjelholt, Peter Krogh Brynningsen, Alma B Pedersen, Søren Paaske Johnsen

Publikováno v: Hjelholt, T J, Johnsen, S P, Brynningsen, P K & Pedersen, A B 2020, ' Association of CHA2 DS2-VASc Score with Stroke, Thromboembolism, and Death in Hip Fracture Patients ', Journal of the American Geriatrics Society, vol. 68, no. 8, pp. 1698-1705 . https://doi.org/10.1111/jgs.16452
Hjelholt, T J, Johnsen, S P, Brynningsen, P K & Pedersen, A B 2020, ' Association of CHA2DS2-VASc Score with Stroke, Thromboembolism, and Death in Hip Fracture Patients ', Journal of the American Geriatrics Society, vol. 68, no. 8, pp. 1698-1705 . https://doi.org/10.1111/jgs.16452

OBJECTIVES: Patients undergoing hip fracture surgery have a 10 times increased risk of stroke compared with the general population. We aimed to evaluate the association between the CHA 2DS 2-VASc (congestive heart failure, hypertension, age ≥75 yea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d60b18cc1af411d1d433dd31004abbc
https://vbn.aau.dk/da/publications/62054d2d-95e3-48c1-9ebb-297abf6204f8

Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients

Autor: Thomas J. Hjelholt, Anni Winckelmann, Jesper Melchjorsen, Lars Østergaard, Martin Tolstrup, Ole S. Søgaard, Lærke V. Munk-Petersen, Thomas A Rasmussen, David C. Montefiori

Publikováno v: Winckelmann, A A, Munk-Petersen, L V, Rasmussen, T A, Melchjorsen, J, Hjelholt, T J, Montefiori, D, Ostergaard, L, Søgaard, O S & Tolstrup, M 2013, ' Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients ', P L o S One, vol. 8, no. 4, pp. e62074 . https://doi.org/10.1371/journal.pone.0062074
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e62074 (2013)

Toll-like receptor (TLR) agonists can reactivate HIV from latently infected cells in vitro. We aimed to investigate the TLR-9 agonist, CPG 7909's in vivo effect on the proviral HIV reservoir and HIV-specific immunity. This was a post-hoc analysis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502829cf74ebf4b63159c5c8586818b4
https://pure.au.dk/portal/da/publications/administration-of-a-tolllike-receptor-9-agonist-decreases-the-proviral-reservoir-in-virologically-suppressed-hivinfected-patients(ba658a84-069b-4949-899e-1e8f8854f3b3).html