Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas J Erichsen"'
Autor:
Thomas J Erichsen, Juergen Klempnauer, Wolfgang Knitsch, Florian W. R. Vondran, Hueseyin Bektas, Till Krech, Ludwig Sedlacek, Lampros Kousoulas, Frank Lehner, Mahmoud Abbas
Publikováno v:
Transplantation. 97:e11-e13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdfed1bfbccc65551512881c67398b71
https://doi.org/10.1097/01.tp.0000438631.21591.1e
https://doi.org/10.1097/01.tp.0000438631.21591.1e
Autor:
André Aehlen, Thomas J. Erichsen, Ursula Ehmer, Sandra Kalthoff, Michael P. Manns, Christian P. Strassburg
Publikováno v:
Journal of Hepatology. 52:570-578
Background & Aims Cholestasis is a serious complication of many liver diseases leading to increased serum bile acids (BA) and their conjugates. Chenodeoxycholic (CDCA) acid is a substrate of the human hepatic UDP-glucuronosyltransferase (UGT) 1A3. UG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1fbf6404e9c52f32dda5f009bbd8ef
https://doi.org/10.1016/j.jhep.2010.01.010
https://doi.org/10.1016/j.jhep.2010.01.010
Autor:
Michael P. Manns, Thomas J. Erichsen, Michael Wehmeier, Tim O. Lankisch, Christian P. Strassburg, Sandra Kalthoff, Nicole Freiberg, Ursula Ehmer
Publikováno v:
The Journal of Molecular Diagnostics. 10:549-552
Gilbert's syndrome causes mild, unconjugated hyperbilirubinemia and is present in approximately 10% of the Caucasian population. The basis of the disorder is a 70% reduction in bilirubin glucuronidation catalyzed by the UDP-glucuronosyltransferase 1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceeddcfecd7a8b3d654b9b0d5ddf5f03
https://doi.org/10.2353/jmoldx.2008.080036
https://doi.org/10.2353/jmoldx.2008.080036
Autor:
Thomas J. Erichsen, Christian P. Strassburg, Tim O. Lankisch, Michael P. Manns, Peter A. Münzel, Ursula Ehmer, Tordis M. Müller, Sandra Kalthoff
Publikováno v:
Toxicology and Applied Pharmacology. 230:252-260
UDP glucuronosyltransferases (UGTs) play an important role for drug detoxification and toxicity. UGT function is genetically modulated by single nucleotide polymorphisms (SNPs) which lead to the expression of functionally altered protein, or altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb169ef0dfb94d58d2bfa57d2104da2b
https://doi.org/10.1016/j.taap.2008.02.020
https://doi.org/10.1016/j.taap.2008.02.020
Autor:
Fabian A. Helfritz, Nikos Emmanouilidis, Ralf-Peter Vonberg, Tim O. Lankisch, Jochen Wedemeyer, Ahmed A. Negm, Thomas J. Erichsen, Sebastian Suerbaum, Michael P. Manns, Henrike Lenzen
Publikováno v:
Digestion. 91(3)
Background/Aims: Postsurgical gastroesophageal intrathoracic leakage is a potentially life-threatening condition that is frequently accompanied by mediastinitis and subsequent sepsis. Aspiration of fluids from intrathoracic leaks during endoscopy for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2ca07d131e51f0019724f9fd555765
https://pubmed.ncbi.nlm.nih.gov/25790934
https://pubmed.ncbi.nlm.nih.gov/25790934
Autor:
Tim O. Lankisch, Thomas J. Erichsen, Michael P. Manns, Jochen Wedemeyer, Henrike Lenzen, Ahmed A. Negm
AIM: To evaluate the efficacy and safety of endoscopic-vacuum assisted closure (E-VAC) therapy in the treatment of cervical esophageal leakage. METHODS: Between May and November 2012, three male patients who developed post-operative cervical esophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f6d87b870a840aede02d609763cda4
https://europepmc.org/articles/PMC3711065/
https://europepmc.org/articles/PMC3711065/
Autor:
Thomas J. Erichsen, Thomas Pietschmann, Sandra Ciesek, Eike Steinmann, Jörg Steinmann, Jochen Steinmann, Pedro Mateu-Gelabert, Martina Friesland, Juliane Doerrbecker
Background. Hepatitis C virus (HCV) cross-contamination from inanimate surfaces or objects has been implicated in transmission of HCV in health-care settings and among injection drug users. We established HCVbased carrier and drug transmission assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767057bd67cd9c037990640632e37c72
https://europepmc.org/articles/PMC3247810/
https://europepmc.org/articles/PMC3247810/
Autor:
Michael P. Manns, Thomas J. Erichsen, Sandra Kalthoff, Peter A. Münzel, Ursula Ehmer, Tracey C. Gillman, Nicole Freiberg, Christian P. Strassburg, Tim O. Lankisch
Publikováno v:
Archives of toxicology. 82(9)
UDP-glucuronosyltransferases contribute to the detoxification of drugs by forming water soluble beta-D-glucopyranosiduronic acids. The human UGT1A3 protein catalyzes the glucuronidation of estrogens, bile acids and xenobiotics including non-steroidal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffb5ca900c2b89ceb8830f640a48fea
https://pubmed.ncbi.nlm.nih.gov/18677463
https://pubmed.ncbi.nlm.nih.gov/18677463
Autor:
Tim O. Lankisch, Thomas Zwingers, Volker Heinemann, Christoph Schulz, Michael P. Manns, Christian P. Strassburg, Thomas J. Erichsen
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 17(3)
Background: Gilbert's syndrome is characterized by a functional promoter single nucleotide polymorphism (SNP) of the UDP-glucuronosyltransferase (UGT) 1A1 gene and represents a pharmacogenetic risk factor for irinotecan toxicity, but study data remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4c058ffc1ccbcf53d7af311572adc1
https://pubmed.ncbi.nlm.nih.gov/18349289
https://pubmed.ncbi.nlm.nih.gov/18349289
Publikováno v:
Clinical Infectious Diseases. 53:963-964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d715a3d66f1b349419556aed5b8970
https://doi.org/10.1093/cid/cir530
https://doi.org/10.1093/cid/cir530