Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thomas J Cremer"'
Autor:
Thomas J Cremer, David H Ravneberg, Corey D Clay, Melissa G Piper-Hunter, Clay B Marsh, Terry S Elton, John S Gunn, Amal Amer, Thirumala-Devi Kanneganti, Larry S Schlesinger, Jonathan P Butchar, Susheela Tridandapani
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8508 (2009)
The intracellular gram-negative bacterium Francisella tularensis causes the disease tularemia and is known for its ability to subvert host immune responses. Previous work from our laboratory identified the PI3K/Akt pathway and SHIP as critical modula
Externí odkaz:
https://doaj.org/article/906f115ebd9345cebacd7a39e827e03c
Autor:
Murugesan V S Rajaram, Jonathan P Butchar, Kishore V L Parsa, Thomas J Cremer, Amal Amer, Larry S Schlesinger, Susheela Tridandapani
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7919 (2009)
Francisella tularensis infects macrophages and escapes phago-lysosomal fusion to replicate within the host cytosol, resulting in host cell apoptosis. Here we show that the Fas-mediated death pathway is activated in infected cells and correlates with
Externí odkaz:
https://doaj.org/article/d7968bac684a46f1b4e8c28013c8d14f
Autor:
Jonathan P Butchar, Thomas J Cremer, Corey D Clay, Mikhail A Gavrilin, Mark D Wewers, Clay B Marsh, Larry S Schlesinger, Susheela Tridandapani
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2924 (2008)
Francisella tularensis is a gram-negative facultative bacterium that causes the disease tularemia, even upon exposure to low numbers of bacteria. One critical characteristic of Francisella is its ability to dampen or subvert the host immune response.
Externí odkaz:
https://doaj.org/article/bd1bb32a8ade4262a7688f8bbfa56bf4
Autor:
Thomas J. Cremer, Estelle Cormet-Boyaka, Daren L. Knoell, Mikhail A. Gavrilin, Anasuya Sarkar, Susheela Tridandapani, Devyn D. Gillette, Jonathan P. Butchar, Beth Y. Besecker, Mark D. Wewers, Prexy Shah
Publikováno v:
Journal of Biological Chemistry. 288:3691-3695
Burkholderia cenocepacia, the causative agent of cepacia syndrome, primarily affects cystic fibrosis patients, often leading to death. In the lung, epithelial cells serve as the initial barrier to airway infections, yet their responses to B. cenocepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432f3c8b2dc5969f5a873c16a12ccd89
https://doi.org/10.1074/jbc.c112.430298
https://doi.org/10.1074/jbc.c112.430298
Publikováno v:
Future Microbiology. 3:503-506
Evaluation of: Ketavarapu JM, Rodriguez AR, Yu J et al.: Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4. Proc. Natl Acad. Sci. USA 105(27), 9313–9318 (2008). The intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef3f6ce1373898bdd6933b17ac39d9de
https://doi.org/10.2217/17460913.3.5.503
https://doi.org/10.2217/17460913.3.5.503
Autor:
John S. Gunn, Thomas J. Cremer, Larry S. Schlesinger, Susheela Tridandapani, Jonathan P. Butchar, Murugesan V. S. Rajaram, Kishore V. L. Parsa
Publikováno v:
Molecular Immunology. 45:3428-3437
Tularemia is a zoonotic disease caused by the Gram-negative intracellular pathogen Francisella tularensis. These bacteria evade phagolysosomal fusion, escape from the phagosome and replicate in the host cell cytoplasm. IFNgamma has been shown to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31c40c16da1592f3823a48274e91805
https://doi.org/10.1016/j.molimm.2008.04.006
https://doi.org/10.1016/j.molimm.2008.04.006
Autor:
David Huehl Ravneberg, Mark D. Wewers, Thomas J. Cremer, Prexy Shah, Larry S. Schlesinger, Susheela Tridandapani, Kavin Fatehchand, Devyn D. Gillette, Heather M. Curry, Mikhail A. Gavrilin, Jonathan P. Butchar
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Background: Human monocyte inflammatory responses differ between virulent and attenuated Francisella infection. Results: A mixed infection model showed that the virulent F. tularensis Schu S4 can attenuate inflammatory cytokine responses to the less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fb76c3f6e6f9f9b79d26b11472ac77
https://doi.org/10.3389/fcimb.2014.00045
https://doi.org/10.3389/fcimb.2014.00045
Autor:
Devyn D. Gillette, Murugesan V. S. Rajaram, Estelle Cormet-Boyaka, Prexy Shah, Rachel L. Marsh, Kavin Fatehchand, Susheela Tridandapani, Thomas J. Cremer, Hemal Patel, Thirumala-Devi Kanneganti, Larry S. Schlesinger, Jonathan P. Butchar, Beth Y. Besecker
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
Frontiers in Cellular and Infection Microbiology, Vol 2 (2012)
MiR-155 regulates numerous aspects of innate and adaptive immune function. This miR is induced in response to toll-like receptor ligands, cytokines, and microbial infection. We have previously shown that miR-155 is induced in monocytes/macrophages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae39b932562b5ca152cbb671ed016d47
http://europepmc.org/articles/PMC3417573
http://europepmc.org/articles/PMC3417573
Autor:
Estelle Cormet-Boyaka, Jonathan P. Butchar, Prexy Shah, Thomas J. Cremer, Susheela Tridandapani, Miguel A. Valvano
The environmental bacterium Burkholderia cenocepacia causes opportunistic lung infections in immunocompromised individuals, particularly in patients with cystic fibrosis. Infections in these patients are associated with exacerbated inflammation leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dd148ba700f7118764e76223bcbd4b
https://europepmc.org/articles/PMC3131456/
https://europepmc.org/articles/PMC3131456/
Publikováno v:
Frontiers in Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Metabolite profiles (GC–−MS), drimane sesquiterpenes, sugars and sugar alcohols, were compared with bacterial and fungal endophyte communities (T-RFLP, DNA clones, qPCR) in leaves and roots of the pepper bark tree, Warburgia ugandensis (Canellace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea226eb2669334429db4ebea6c06ee5
http://europepmc.org/articles/PMC3109490
http://europepmc.org/articles/PMC3109490