Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Thomas J, Walters"'
Autor:
Thomas J. Walters, Luciana N. Torres, Kathy L. Ryan, Robert V. Hainline, Stephanie M. Lipiec, Ijeoma E. Obi, Jennifer Ybarra, Casey E. Niland, Lusha Xiang
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2607 (2024)
Extremity trauma, including ischemia (e.g., prolonged tourniquet application or crush), is common among battlefield injuries. Injured muscle releases toxins leading to rhabdomyolysis and, potentially, acute kidney injury (AKI). The goal of this study
Externí odkaz:
https://doaj.org/article/3a27811472844f69b8134eeacb9a6575
Autor:
Sarah E. Dyer, J. David Remer, Kelsey E. Hannifin, Aishwarya Hombal, Joseph C. Wenke, Thomas J. Walters, George J. Christ
Publikováno v:
J Appl Physiol (1985)
Extended tourniquet application, often associated with battlefield extremity trauma, can lead to severe ischemia-reperfusion (I/R) injury in skeletal muscle. Particulate oxygen generators (POGs) can be directly injected into tissue to supply oxygen t
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191245 (2018)
Minced muscle autografting mediates de novo myofiber regeneration and promotes partial recovery of neuromuscular strength after volumetric muscle loss injury (VML). A major limitation of this approach is the availability of sufficient donor tissue fo
Externí odkaz:
https://doaj.org/article/6efe8770f64549a3859acf73eba0a071
Publikováno v:
Annals of Vascular Surgery. 76:59-65
Introduction Lower extremity (LE) arterial injuries are common in military casualties and limb salvage is a primary goal. Bypass grafts are the most common reconstructions; however, their specific outcomes are largely unreported. We sought to describ
Autor:
Thomas J. Walters, David S. Kauvar, Lydia C. Piper, Jessica C. Rivera, Amanda M Staudt, Kathy L. Ryan, Brandon W. Propper, Zachary M. Arthurs
Publikováno v:
Journal of Surgical Research. 260:409-418
Background Military guidelines endorse early fasciotomy after revascularization of lower extremity injuries to prevent compartment syndrome, but the real-world impact is unknown. We assessed the association between fasciotomy and amputation and limb
Publikováno v:
Annals of Vascular Surgery. 70:95-100
Effective amputation prediction may help inform appropriate early limb salvage efforts in military lower extremity (LE) arterial injury. The Mangled Extremity Severity Score (MESS) is the most commonly applied system for early amputation prediction b
Publikováno v:
Annals of Vascular Surgery. 62:119-127
By necessity, wartime arterial injuries undergo staged management. Initial procedures may occur at a forward surgical team (role 2), where temporary shunts can be placed before transfer to a larger field hospital (role 3) for definitive reconstructio
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Skeletal muscle repair after injury includes a complex and well-coordinated regenerative response. However, fibrosis often manifest, leading to aberrant regeneration and incomplete functional recovery. Research efforts have focused on the use of anti
Externí odkaz:
https://doaj.org/article/4bc0cf5dd40740b2a733c723017a0eda
Publikováno v:
Journal of Trauma and Acute Care Surgery. 87:S59-S66
Acute compartment syndrome (ACS) is a serious medical condition that can occur following traumatic injury to an extremity. If left undiagnosed, ACS can eventuate in amputation of the limb or even death. Because of this, fasciotomy to release the pres
Publikováno v:
Acta Biomaterialia. 65:150-162
Extracellular matrix (ECM) scaffolds are being used for the clinical repair of soft tissue injuries. Although improved functional outcomes have been reported, ECM scaffolds show limited tissue specific remodeling response with concomitant deposition