Výsledky vyhledávání - "Thomas J, Podor"

Effects of granulocyte-colony stimulating factor on bone marrow-derived progenitor cells in murine cardiac transplantation

Autor: Xiaozhen Wang, Joanna Leung, Theresa A. Deisher, Thomas J. Podor, Alexandra Kerjner, Heather L. Heine, Stéphane Y. Corbel, Nana Rezai, Fabio M.V. Rossi, Bruce M. McManus

Publikováno v: Cardiovascular Pathology. 19:36-47

Granulocyte-colony stimulating factor (G-CSF) mobilizes progenitors from the bone marrow (BM) and into the circulation. In cardiac transplantation, G-CSF pretreatment of both donors and recipients has been found to improve cardiac function. The aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e99c61cc9fd96eddab1ba01f213bce4
https://doi.org/10.1016/j.carpath.2008.10.007

Zobrazit plný text záznamu

Vimentin autoantibodies induce platelet activation and formation of platelet-leukocyte conjugates via platelet-activating factor

Autor: J. R. Day, Marlene L. Rose, Gopal Ghimire, A. D. McCormack, John D. Smith, Hon S. Leong, Thomas J. Podor, Balakrishnan Mahesh

Publikováno v: Journal of Leukocyte Biology. 83:263-271

Anti-vimentin antibodies (AVA) are asso- ciated with autoimmunity and solid organ transplan- tation, conditions associated with vascular disease, but their contribution to disease pathogenesis is un- known. Here, we have examined interactions be- twe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea8ffd6a48cbc76add81608aed417ed
https://doi.org/10.1189/jlb.0607339

Zobrazit plný text záznamu

Bone marrow-derived recipient cells in murine transplanted hearts: potential roles and the effect of immunosuppression

Autor: Darya Dabiri, Alexandra Kerjner, Bruce M. McManus, Thomas J. Podor, Fabio M.V. Rossi, Nana Rezai, Stéphane Y. Corbel

Publikováno v: Laboratory Investigation. 85:982-991

Currently, there is intense debate regarding the origin of reparative cells in injured hearts and vasculature. To determine the contribution of recipient bone marrow (BM)-derived cells to the regeneration of cells in the vasculature of transplanted h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f58898b658291a9b3059e9416567a3
https://doi.org/10.1038/labinvest.3700302

Zobrazit plný text záznamu

Bone Marrow Cells in the Repair and Modulation of Heart and Blood Vessels: Emerging Opportunities in Native and Engineered Tissue and Biomechanical Materials

Autor: Nana Rezai, Thomas J. Podor, Bruce M. McManus

Publikováno v: Artificial Organs. 28:142-151

Adult bone marrow-derived stem/progenitor cells have traditionally been considered to be tissue-specific cells with limited capacity for differentiation. However, recent discoveries have generated tremendous excitement regarding possible applications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a157b089909b68040cea2e7716d9205
https://doi.org/10.1111/j.1525-1594.2004.47334.x

Zobrazit plný text záznamu

The Regulation and Consequences of Immune-Mediated Cell Death in Atheromatous Diseases

Autor: Jonathan C. Choy, Bobby Yanagawa, Bruce M. McManus, John C.K. Lai, Thomas J. Podor, David J. Granville, David C. Walker

Publikováno v: Cardiovascular Toxicology. 3:269-282

Atheromatous diseases are lipid and cell-rich vascular disorders that include coronary artery disease (CAD), transplant vascular disease (TVD), and restenosis. Considering the inflammatory nature of these diseases, cytotoxic immune mechanisms such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d14ede958239f9b76e565202aa8a34f
https://doi.org/10.1385/ct:3:3:269

Zobrazit plný text záznamu

Incorporation of Vitronectin into Fibrin Clots

Autor: Philip D. Walton, Cynthia B. Peterson, David H. Farrell, Stephanie Campbell, Thomas J. Podor, Jeffrey I. Weitz, Paul A. Chindemi, Denise M. Foulon

Publikováno v: Journal of Biological Chemistry. 277:7520-7528

Vitronectin is an abundant plasma protein that regulates coagulation, fibrinolysis, complement activation, and cell adhesion. Recently, we demonstrated that plasma vitronectin inhibits fibrinolysis by mediating the interaction of type 1 plasminogen a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8a9a4ff16b6b6ff094ca7bedbdc2e89
https://doi.org/10.1074/jbc.m109677200

Zobrazit plný text záznamu

Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface

Autor: Richard C. Austin, Davindra Singh, Ghislain Boudreau, Richard F. Davies, Robert S. McKelvie, Thomas J. Podor, Jeffrey I. Weitz, Paul A. Chindemi, Denise M. Foulon

Publikováno v: Journal of Biological Chemistry. 277:7529-7539

Type 1 plasminogen activator inhibitor (PAI-1), the primary inhibitor of tissue-type plasminogen activator (t-PA), is found in plasma and platelets. PAI-1 circulates in complex with vitronectin (Vn), an interaction that stabilizes PAI-1 in its active

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c57931ab1fb90d1e29d4c5b49f67fb
https://doi.org/10.1074/jbc.m109675200

Zobrazit plný text záznamu

New Insights into the Size and Stoichiometry of the Plasminogen Activator Inhibitor Type-1·Vitronectin Complex

Autor: Michael N. Blackburn, Stephen G. Shaughnessy, Thomas J. Podor, Cynthia B. Peterson

Publikováno v: Journal of Biological Chemistry. 275:25402-25410

Plasminogen activator inhibitor-type 1 (PAI-1) is the primary inhibitor of endogenous plasminogen activators that generate plasmin in the vicinity of a thrombus to initiate thrombolysis, or in the pericellular region of cells to facilitate migration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af1bf91590cb3dc298e31d0e5dc6f24
https://doi.org/10.1074/jbc.m000362200

Zobrazit plný text záznamu

The Binding of Unfractionated Heparin and Low Molecular Weight Heparin to Thrombin-Activated Human Endothelial Cells

Autor: Stephen G. Shaughnessy, Thomas J. Podor, Jack Hirsh, José C.O Ribau, Thomas J. Venner, Edward Young

Publikováno v: Thrombosis Research. 96:373-381

The binding of unfractionated heparin to endothelium is thought to be responsible for the rapid and saturable phase of unfractionated heparin clearance. Thrombin can induce endothelial cells to express and/or secrete a number of heparin binding prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264a6664f31763b89fe14d0eeba51a14
https://doi.org/10.1016/s0049-3848(99)00125-5

Zobrazit plný text záznamu

Homocysteine-Induced Endoplasmic Reticulum Stress and Growth Arrest Leads to Specific Changes in Gene Expression in Human Vascular Endothelial Cells

Autor: J. I. Weitz, Jun Li, Sudesh K. Sood, S. I. Pfeifer, Thomas J. Podor, P. A. Outinen, Sushmita Pamidi, Richard C. Austin

Publikováno v: Blood. 94:959-967

Alterations in the cellular redox potential by homocysteine promote endothelial cell (EC) dysfunction, an early event in the progression of atherothrombotic disease. In this study, we demonstrate that homocysteine causes endoplasmic reticulum (ER) st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c904b07c0f970a31b65db09e4468882
https://doi.org/10.1182/blood.v94.3.959.415k20_959_967

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání