Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas J, Moutinho"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009341 (2022)
Genome-scale metabolic network reconstructions (GENREs) are valuable tools for understanding microbial metabolism. The process of automatically generating GENREs includes identifying metabolic reactions supported by sufficient genomic evidence to gen
Externí odkaz:
https://doaj.org/article/ebafa65a0cb7490a8e834ebe41b83a7c
Publikováno v:
JMIR Human Factors, Vol 8, Iss 3, p e27452 (2021)
BackgroundDiet and nutrition management is an integral component of Crohn disease (CD) management. This type of management is highly variable and individualized and, thus, requires personalized approaches. Consumer health information technology (CHIT
Externí odkaz:
https://doaj.org/article/12a5482e836f42878529258b3ddfb398
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007847 (2020)
Uncertainty in the structure and parameters of networks is ubiquitous across computational biology. In constraint-based reconstruction and analysis of metabolic networks, this uncertainty is present both during the reconstruction of networks and in s
Externí odkaz:
https://doaj.org/article/1f5d401be3874db2965ec30d49d82702
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007099 (2020)
The metabolic responses of bacteria to dynamic extracellular conditions drives not only the behavior of single species, but also entire communities of microbes. Over the last decade, genome-scale metabolic network reconstructions have assisted in our
Externí odkaz:
https://doaj.org/article/832bfc8fafa54838ab04dc02b0df07aa
Autor:
Thomas J. Moutinho, Deborah A. Powers, Gabriel F. Hanson, Shira Levy, Rajiv Baveja, Isabel Hefner, Masouma Mohamed, Alaa Abdelghani, Robin L. Baker, Jason A. Papin, Sean R. Moore, Suchitra K. Hourigan
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 46:1903-1913
Parenteral nutrition-associated cholestasis (PNAC) in the neonatal intensive care unit (NICU) causes significant morbidity and associated healthcare costs. Laboratory detection of PNAC currently relies on elevated serum conjugated bilirubin levels in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dd7b7bd3e94f27564a026623672535
https://doi.org/10.1002/jpen.2374
https://doi.org/10.1002/jpen.2374
Autor:
Thomas J Moutinho, John C Panagides, Matthew B Biggs, Gregory L Medlock, Glynis L Kolling, Jason A Papin
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182163 (2017)
Interactions between microbes are central to the dynamics of microbial communities. Understanding these interactions is essential for the characterization of communities, yet challenging to accomplish in practice. There are limited available tools fo
Externí odkaz:
https://doaj.org/article/fc1b8771b0c249f7ace3c6c93df13d5d
Autor:
Jibraan A, Fawad, Deborah H, Luzader, Gabriel F, Hanson, Thomas J, Moutinho, Craig A, McKinney, Paul G, Mitchell, Kathleen, Brown-Steinke, Ajay, Kumar, Miri, Park, Suengwon, Lee, David T, Bolick, Greg L, Medlock, Jesse Y, Zhao, Andrew E, Rosselot, C James, Chou, Emily M, Eshleman, Theresa, Alenghat, Christian I, Hong, Jason A, Papin, Sean R, Moore
Publikováno v:
Gastroenterology. 163:1377-1390.e11
The circadian clock orchestrates ∼24-hour oscillations of gastrointestinal epithelial structure and function that drive diurnal rhythms in gut microbiota. Here, we use experimental and computational approaches in intestinal organoids to reveal reci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723e33d7dadb14fb305019b85348a6ed
https://doi.org/10.1053/j.gastro.2022.07.051
https://doi.org/10.1053/j.gastro.2022.07.051
Genome-scale metabolic network reconstructions (GENREs) are valuable tools for understanding microbial community metabolism. The process of automatically generating GENREs includes identifying metabolic reactions supported by sufficient genomic evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2dad9325af4e56635d633bc1aa26eb
https://doi.org/10.1101/2021.08.13.456222
https://doi.org/10.1101/2021.08.13.456222
BACKGROUND Diet and nutrition management is an integral component of Crohn disease (CD) management. This type of management is highly variable and individualized and, thus, requires personalized approaches. Consumer health information technology (CHI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066cd7ea26fecd7d85b20147a16dd409
https://doi.org/10.2196/preprints.27452
https://doi.org/10.2196/preprints.27452
Autor:
C. J. Chou, Kathleen Brown-Steinke, Andrew E. Rosselot, P. G. Mitchell, Jason A. Papin, Thomas J. Moutinho, Sean R. Moore, C. A. McKinney, Deborah Luzader, Christian I. Hong, J. Y. Zhao, Jibraan A. Fawad
Background and aimsThe circadian clock orchestrates ~24-hour oscillations of gastrointestinal (GI) epithelial structure and function that drive diurnal rhythms in the composition, localization, and metabolism of gut microbiota. Here, we use experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::decdd49fe11bb7157416d04298192cbf
https://doi.org/10.1101/2020.06.09.143057
https://doi.org/10.1101/2020.06.09.143057