Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas Ippolito"'
Autor:
Francisco J. Hernandez-Ilizaliturri, Cory Mavis, Juan Gu, Matthew J. Barth, Thomas Ippolito, Mitchell S. Cairo, Maria Bhatti, Megan S. Lim
Publikováno v:
Oncotarget
Though outcomes for pediatric Burkitt lymphoma (BL) have improved significantly in recent decades with intensive multi-agent chemotherapy and the addition of rituximab, chemotherapy resistance remains a significant impediment to cure following relaps
Autor:
Thomas Ippolito, Juan J Gu, Tara Daly, Matthew J. Barth, Pallawi Torka, Cory Mavis, Francisco J. Hernandez-Ilizaliturri
Publikováno v:
Blood. 134:5303-5303
Background: Although >90% of Burkitt Lymphoma (BL) patients will be cured by intensive multi-agent immunochemotherapy, relapsed and refractory BL patients have poor prognoses demonstrating the need to identify novel therapies. Myeloid cell leukemia-1
Autor:
Thomas Ippolito, Dhammika Gunasekera, Angelo H. Gunasekera, Javan Esfandiari, Jillian M. Cappello
Publikováno v:
Journal of Clinical Virology. 58:e59-e64
Background Multicenter studies were conducted to evaluate the DPP ® HIV 1/2 Assay using oral fluid (OF) and fingerstick (FS) specimens in two different countries at the point of care (POC). Objective To evaluate the DPP ® HIV 1/2 Assay using OF and
Autor:
Thomas Ippolito, Francisco J. Hernandez-Ilizaliturri, Matthew J. Barth, Rodney R. Miles, Cory Mavis, Vladimir Rodic
Publikováno v:
Blood. 132:1586-1586
Background: Copy number gain and/or MYC induction leads to increased expression of miRs in the miR-17~92 cluster. Development of Burkitt lymphoma (BL) is associated with translocation of MYC resulting in MYC expression and frequent recurrent copy num
Autor:
Thomas Ippolito, Matthew J. Barth, Greg Tang, Cory Mavis, Francisco J. Hernandez-Ilizaliturri, Juan J Gu
Publikováno v:
Blood. 132:2951-2951
Background: Despite significant gains achieved in the treatment of Burkitt lymphoma (BL), current multi-agent immunochemotherapeutic regimens lead to high rates of acute toxicity, and relapsed/refractory disease still represents a significant hurdle
Autor:
Thomas Ippolito, Kyle Bonneau, Andrei V. Gudkov, Venkatesh Natarajan, Alex Chenchik, Andrei P. Komarov
Publikováno v:
Proceedings of the National Academy of Sciences. 111
Chronic inflammation is associated with increased cancer risk. Furthermore, the transcription factor NF-κB, a central regulator of inflammatory responses, is constitutively active in most tumors. To determine whether active NF-κB inherently contrib
Autor:
Francisco J. Hernandez-Ilizaliturri, Matthew J. Barth, Gregory Tang, Cory Mavis, Thomas Ippolito, Rodney R. Miles, Juan J Gu
Publikováno v:
Blood. 128:5381-5381
Background: Burkitt lymphoma (BL) is the most common NHL type in children. Although treatment for pediatric BL has improved significantly, there is an urgent need for novel therapies that reduce the toxicity of modern treatment regimens and improve o
Autor:
Mircea Cotlet, Mudalige Kumara, Thomas Ippolito, Jonathan D. Trent, Basil I. Swanson, Hongzhi Xie, Hiromi K. Kawaga
Publikováno v:
SPIE Proceedings.
We describe genetic engineering of a novel protein-nanoparticle hybrid system with great potential for patterning of various types of nanoparticles and for biosensing applications. The hybrid system is based on a genetically-modified chaperonin prote
PI3K/Akt/mTOR Pathway Inhibition in Chemotherapy-Sensitive and -Resistant Models of Burkitt Lymphoma
Publikováno v:
Blood. 126:1558-1558
Introduction: Burkitt lymphoma (BL) is the most common form of B-cell non-Hodgkin lymphoma (B-NHL) in children. Despite significant improvements in survival with de novo disease, treatment of relapsed or refractory BL remains a significant hurdle wit