Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Thomas I, Zarembinski"'
1
Akademický článek
Micropatterning of 3D Microenvironments for Living Biosensor Applications
Autor: William F. Hynes, Nate J. Doty, Thomas I. Zarembinski, Michael P. Schwartz, Michael W. Toepke, William L. Murphy, Sarah K. Atzet, Ryan Clark, J. Andres Melendez, Nathaniel C. Cady
Publikováno v: Biosensors, Vol 4, Iss 1, Pp 28-44 (2014)
Micro-scale printing and patterning of living cells has multiple applications including tissue engineering, cell signaling assays, and the fabrication of cell-based biosensors. In this work, a molecular printing instrument, the Bioforce Nano eNabler,
Externí odkaz: https://doaj.org/article/988a9f12b96948799415eec6e7c8d3f7
Zobrazit plný text záznamu
2
Intraocular Injection of HyStem Hydrogel Is Tolerated Well in the Rabbit Eye
Autor: Francois Binette, Maria M Campos, Thomas I. Zarembinski, Michael O'Boyle, Igor O. Nasonkin, Ratnesh K. Singh, Randolph D. Glickman, Michael Onorato
Publikováno v: J Ocul Pharmacol Ther
Purpose: To determine the long-term biocompatibility of HyStem(®) hydrogel in the rabbit eye for use as a carrier for cell or drug delivery into the ocular space. Methods: HyStem hydrogel formulation solidifies ∼20 min after reconstitution, thus c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62869492044f1f931c4937f5f59edd34
https://doi.org/10.1089/jop.2020.0042
Zobrazit plný text záznamu
3
Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity
Autor: Airi, Harui, Sandra M, McLachlan, Basil, Rapoport, Thomas I, Zarembinski, Michael D, Roth
Publikováno v: Cancer immunology, immunotherapy : CII. 69(9)
Combination immunotherapy targeting the PD-1 and CTLA-4 checkpoint inhibitor pathways provides substantial clinical benefit in patients with advanced-stage cancer but at the risk of dose-limiting inflammatory and autoimmune toxicity. The delicate bal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81ab8cba634f71b1120c2bf1d3698ba9
https://pubmed.ncbi.nlm.nih.gov/32333082
Zobrazit plný text záznamu
4
Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering
Autor: Urmi Sheth, Giovanni A. Botten, Christopher C.W. Hughes, Medha M. Pathak, Heather J. Wright, Elliot L. Botvinick, Lisa A. Flanagan, Daniel S. Yanni, Janahan Arulmoli, Richard Que, Duc T. T. Phan, Olga V. Razorenova, Mark Keating, Thomas I. Zarembinski
Publikováno v: Acta biomaterialia
Arulmoli, J; Wright, HJ; Phan, DTT; Sheth, U; Que, RA; Botten, GA; et al.(2016). Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. ACTA BIOMATERIALIA, 43, 122-138. doi: 10.1016/j.actbio.2016.07.043. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/44r975rg
Human neural stem/progenitor cells (hNSPCs) are good candidates for treating central nervous system (CNS) trauma since they secrete beneficial trophic factors and differentiate into mature CNS cells; however, many cells die after transplantation. Thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b992784679cec167119c8cf54a3df719
http://europepmc.org/articles/PMC5386322
Zobrazit plný text záznamu
5
Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem
Autor: Kristine, Ravina, Denise I, Briggs, Sezen, Kislal, Zuha, Warraich, Tiffany, Nguyen, Rachel K, Lam, Thomas I, Zarembinski, Mehrdad, Shamloo
Publikováno v: International Journal of Molecular Sciences
Ischemic stroke is a leading cause of death and disability worldwide. Potential therapeutics aimed at neural repair and functional recovery are limited in their blood-brain barrier permeability and may exert systemic or off-target effects. We examine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d019312cfdf2a5f7470a5f390938e78
https://pubmed.ncbi.nlm.nih.gov/30486515
Zobrazit plný text záznamu
6
Intracerebral Delivery of Brain-Derived Neurotrophic Factor Using HyStem®-C Hydrogel Implants Improves Functional Recovery and Reduces Neuroinflammation in a Rat Model of Ischemic Stroke
Autor: Rachel K. Lam, Sezen Kislal, Denise I. Briggs, Thomas I. Zarembinski, Tiffany Nguyen, Mehrdad Shamloo, Kristine Ravina, Zuha Warraich
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 12, p 3782 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 12
Ischemic stroke is a leading cause of death and disability worldwide. Potential therapeutics aimed at neural repair and functional recovery are limited in their blood-brain barrier permeability and may exert systemic or off-target effects. We examine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb064ef81edceb7a8a9d531e8b412ba
https://www.mdpi.com/1422-0067/19/12/3782
Zobrazit plný text záznamu
7
Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures
Autor: Lindsey K. Sablatura, Brian J. Engel, Daniel D. Carson, Pamela E. Constantinou, Daniel A. Harrington, Mary C. Farach-Carson, Nathaniel J. Doty, Thomas I. Zarembinski
Publikováno v: Advanced Healthcare Materials. 4:1664-1674
Validation of a high-throughput compatible 3D hyaluronic acid hydrogel coculture of cancer cells with stromal cells. The multilayered hyaluronic acid hydrogels improve drug screening predictability as evaluated with a panel of clinically relevant che
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5848bf11fb71824cd5a8317965815e13
https://doi.org/10.1002/adhm.201500258
Zobrazit plný text záznamu
9
The effect of mesenchymal stromal cell sheets on the inflammatory stage of flexor tendon healing
Autor: Shelly E. Sakiyama-Elbert, Isaac Erickson, Necat Havlioglu, Stephen W. Linderman, Stavros Thomopoulos, Richard H. Gelberman, Ioannis Kormpakis, Thomas I. Zarembinski, Matthew J. Silva, Hua Shen
Publikováno v: Stem Cell Research & Therapy
Background The clinical outcomes following intrasynovial flexor tendon repair are highly variable. Excessive inflammation is a principal factor underlying the formation of adhesions at the repair surface and affecting matrix regeneration at the repai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ce2e24be75ed09ad8fc9d1d066b911
http://europepmc.org/articles/PMC5039894
Zobrazit plný text záznamu
10
Hydrogel-delivered brain-derived neurotrophic factor promotes tissue repair and recovery after stroke
Autor: Thomas I. Zarembinski, Cynthia Nguyen, Hyun N Chun, S. Thomas Carmichael, Douglas J. Cook, Michal Machnicki, Irene L. Llorente, Abraham S Chiu
Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 37, iss 3
Stroke is the leading cause of adult disability. Systemic delivery of candidate neural repair therapies is limited by the blood–brain barrier and off-target effects. We tested a bioengineering approach for local depot release of BDNF from the infar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414b2d44c721ad64c380995bac09ba8e
https://europepmc.org/articles/PMC5363479/
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje