Rip it, stitch it, click it: A Chemist's guide to VLP manipulation

Autor: Yalini H. Wijesundara, Fabian C. Herbert, Sneha Kumari, Thomas Howlett, Shailendra Koirala, Orikeda Trashi, Ikeda Trashi, Noora M. Al-Kharji, Jeremiah J. Gassensmith

Publikováno v: Virology. 577:105-123

Viruses are some of nature's most ubiquitous self-assembled molecular containers. Evolutionary pressures have created some incredibly robust, thermally, and enzymatically resistant carriers to transport delicate genetic information safely. Virus-like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160fa0228c4a6c3531500dcaaea08cf0
https://doi.org/10.1016/j.virol.2022.10.008

Carrier gas triggered controlled biolistic delivery of DNA and protein therapeutics from metal–organic frameworks

Autor: Yalini H. Wijesundara, Fabian C. Herbert, Orikeda Trashi, Ikeda Trashi, Olivia R. Brohlin, Sneha Kumari, Thomas Howlett, Candace E. Benjamin, Arezoo Shahrivarkevishahi, Shashini D. Diwakara, Sachini D. Perera, Samuel A. Cornelius, Juan P. Vizuet, Kenneth J. Balkus, Ronald A. Smaldone, Nicole J. De Nisco, Jeremiah J. Gassensmith

Publikováno v: Chemical Science. 13:13803-13814

The efficacy and specificity of protein, DNA, and RNA-based drugs have made them popular in the clinic; however, their susceptibility to environmental stressors adds significant challenges to formulating biomacromolecules into delivery systems where

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cc456fd1e1120991f0a32abfd2d3f6
https://doi.org/10.1039/d2sc04982a

Metal-Organic Framework Encapsulated Whole-Cell Vaccines Enhance Humoral Immunity against Bacterial Infection

Autor: Molly A. Ingersoll, Sundharamani Venkitapathi, Thomas Howlett, Nicole J. De Nisco, Michael A. Luzuriaga, Olivia R. Brohlin, Kavya Veera, Fabian C. Herbert, Jashkaran Gadhvi, Michael D. Burton, Arezoo Shahrivarkevishahi, Candace E. Benjamin, Ryanne Ehrman, Jeremiah J. Gassensmith, Yalini H. Wijesundara, Sarah Popal

Publikováno v: ACS Nano
ACS Nano, American Chemical Society, 2021, ⟨10.1021/acsnano.1c03092⟩
ACS Nano, 2021, ⟨10.1021/acsnano.1c03092⟩

The increasing rate of resistance of bacterial infection against antibiotics requires next generation approaches to fight potential pandemic spread. The development of vaccines against pathogenic bacteria has been difficult owing, in part, to the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f314c9fe1dbd1f84af7c33b1a23d374f
https://doi.org/10.1101/2020.06.14.148452

Parent and anesthetist attitudes toward rectal analgesic suppositories in pediatric daycase surgery: A multi-center cross-sectional survey

Autor: Thomas Howlett, Ruairi Irwin, Sean Keane

Publikováno v: Pediatric Anesthesia. 28:372-373

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48463b3146df7796cc951866026c7b04
https://doi.org/10.1111/pan.13346

Abstract

Autor: Douglas D. Snider, Brendan T. Finucane, Donna Clarke, J. Loiselle, G. Doak, B. Anderson, Dan Wood, Sandy Shysh, Michel-Antoine Perrault, Philippe Chouinard, François Fugère, François Girard, Monique Ruel, Wendy C. E. Hall, Jiri Hrazdil, Donald T. Jolly, John C. Galbraith, Maria C. Greacen, Alexander S. Clanachan, Duminda N. Wijeysundera, W. Scott Beattie, Michelle Chochinov, Stephen Halpern, Dolores M. McKeen, Robert T. Nunn, Brendan S. Barrett, G. Allen Finley, Susan Buffett-Jerrott, Sherry Stewart, Donna Millington, Keyvan Karkouti, Yoga R. Rampersaud, Stuart A. McCluskey, Lucia Evans, Mohammed M. Ghannam, Nizar N. Mahomed, Sudha Singh, Patricia Morley-Forster, Mohammed Shamsah, Ian R. Thomson, Aaron D. Brown, Jeffrey I. Freedman, Robert J. Hudson, Murray Hong, Sean Hall, Brian Milne, Louie Wang, Chris Loomis, Ian Gilron, Debbie Tod, Allan Bell, Elizabeth Orr, Gary Dobson, Mustafa Karamanoglu, John V. Tyberg, Frances Chung, Charles Imarengiaye, Angela Rocchi, Lindy Forte, Elizabeth G. Van Den Kerkhof, David H. Goldstein, Mike Rimmer, Hoi Kwan Lee, Isabelle Charest, René Martin, François Plante, Shaheen Shaikh, Damian Yung, Mark Bernstein, Ngozi Imasogie, David Wong, Ken Luk, Suntheralingam Yogendran, Atul Prabhu, Ayman Hendy, Glenn McGuire, Jean Wong, M. Denise Daley, Peter H. Norman, Una Srejic, Thomas Dougherty, Sarah Hogervorst, Thomas M. Hemmerling, Joachim Schmidt, Pierre Beaulieu, Klaus E. Jacobi, Pamela H. Lennox, Kelly V. Mayson, Toshimi Arai, Kaori Saito, Masao Yamashita, Alain Gauthier, Daniel Boudreault, Dominique C. Girard, Louie T. S. Wang, Nancy Sikich, Guy Petroz, Jerrold Lerman, Gregory M. T. Hare, Andrew J. Baker, Kathryn M. Hum, Steve Y. Kim, Aiala Barr, C. David Mazer, Terrance A. Yemen, Thomas Howlett, Andrew Baker, Nicholas Phan, N. Persaud, Min Zhao, Elaine Liu, Michael Fehlings, Davinia E. Withington, T. AlAyed, G. Michael Davis, David M. Ansley, B. S. Dhaliwal, Zhengyuan Xia, Anthony M. -H. Ho, Anna Lee, Elizabeth Ling, Alan Daly, Kevin Teoh, Theodore E. Warkentin, David V. Godin, Thomas K. H. Chang, Joanne D. Fortier, Fadi Basile, Ignacio Prieto, David Mazer, Peter Duke, Barry Finegan, Davy Cheng, Richard Hall, B. Lim, J. Shannon, C. M. Ho, S. K. Tsai, Margaret Srebrnjak, Vivien Walsh, Geena Joseph, Teresa Valois Gomez, Carmen Rivero Fuenmayor, Paul S. Bach, Allaudin Kamani, Joanne Douglas, Mark Esler, Vit Gunka, Pamela Angle, Sam Tang, Dorothy Thompson, Jean Kronberg, Anwar Morgan, Craig H. Leicht, Ivan A. Velickovic, David T. Raphael, Maxim Benbassat, Dimiter Arnaudov, Alex Bohorquez, Bita Nasseri, D. John Doyle, Jacelyn Kolman, Ian Keith, Pamela J. Morgan, Doreen Cleave-Hogg, Susan Eveleigh, Jordan Tarshis, Sharon Davies, John Doyle, Heather Lee Loughlin, J. Patrick O’Connor, John F. Dolman, Fred S. Mikelberg, Gordana Dulovic, Brian G. Feagan, Cindy J. Wong, Alexandra Kirkley, D. W. C. Johnston, Frank C. Smith, Paul Whitsitt, William Li Pi Shanl, Steven B. Backman, Jeffrey Barkun, Peter Metrakos, John Tchervenkov, Mary Jane Salpeter, Leah Jamnicky, Michael Jewett, Ramiro Arellano, Brian Muirhead, Saifundin Rashiq, Meera Shah, Vikki Wilkinson, Samantha J. Woolsey, Barry A. Finegan, Carol Fiorilli, Joel L. Parlow, Nicole D. Avery, George N. Djaiani, Jayanta Muhkerji, Jacek M. Karski, Jo A. Carroll, Stuart McCluskey, Linda Harris, Jan Paton, Emmanuel Kanetos, William G. Williams, Cristina Hurtado, Manoj Gandhi, Sandy Clanachan, Woo Jong Shin, Bruce, D. Winegar, Jae Hang Shim, Woo Jae Jeon, Kyung Hun Kim, Bing Wang, David P. Archer, Naaznin Samanani, Sheldon H. Roth, Claudia Coimbra, Manon Choinière, Denis Babin, Francois Donati, Cynthia L. Henderson, John H. P. Friesen, Michael Jacka, Alan Cheng, Finlay McAlister, Jessie A. Leak, Tao Bui, Dy Nguyen, Alicia Kowalski, Keruyi Popat, Henry Kuerer, Paul Serowka, Kim Turner, Ted Ashbury, Tianlong Wang, Driss El-Kebir, Bernard Hubert, Ruud A. W. Veldhuizen, Dominique Gauvin, Gilbert Blaise, Fan Yang, Patricia Amicone

Publikováno v: Canadian Journal of Anaesthesia. 49:A60-A148

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b6e5db8d663fbfb97fef7ed852c3d4d
https://doi.org/10.1007/bf03018138