Zobrazeno 1 - 8
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pro vyhledávání: '"Thomas Holst‐Hansen"'
Autor:
Thomas Holst-Hansen, Pernille Yde Nielsen, Mogens H. Jensen, Thomas Mandrup-Poulsen, Ala Trusina
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Type 2 diabetes (T2D) is associated with a systemic increase in the pro-inflammatory cytokine IL-1β. While transient exposure to low IL-1β concentrations improves insulin secretion and β-cell proliferation in pancreatic islets, prolonged
Externí odkaz:
https://doaj.org/article/a2ec5519be3141949357ae26ecb70924
Publikováno v:
Bjorner, J B, Larsen, S, Lübker, C & Holst-Hansen, T 2023, ' The improved health utility of once-weekly subcutaneous semaglutide 2.4 mg compared with placebo in the STEP 1-4 obesity trials ', Diabetes, Obesity and Metabolism, vol. 25, no. 8, pp. 2142-2150 . https://doi.org/10.1111/dom.15090
AIMS: Clinicians and regulatory authorities are placing increasing emphasis on health-related quality of life (HRQoL) and health utilities when evaluating therapeutic efficacy of new agents. We assessed health utility values in the Semaglutide Treatm
Autor:
Pavol Kral, Thomas Holst-Hansen, Anamaria-Vera Olivieri, Cristina Ivanescu, Mark Lamotte, Sara Larsen
Purpose The correlation between body mass index (BMI) and utility in patients with overweight or obesity was assessed using health-related quality of life (HRQoL) data collected in two weight-loss interventional studies, SCALE and STEP 1. Methods Sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec4305f877d6c1c729cb1411306ee1c
https://doi.org/10.21203/rs.3.rs-2096929/v1
https://doi.org/10.21203/rs.3.rs-2096929/v1
Publikováno v:
Diabetes. 71
The effect of once-weekly s.c. semaglutide 2.4 mg (sema) on the risk of developing T2D in people with obesity is unknown. Weight management with sema vs. PBO plus diet/exercise was assessed in participants (pts) with overweight/obesity in STEP 1 (68
Autor:
Andrew Wang, Ala Trusina, Minjun Son, Savaş Tay, Sara Saheb Kashaf, Thomas Holst-Hansen, Tino Frank, Michael Junkin
Publikováno v:
Science Advances, 8 (35)
Son, M, Frank, T, Holst-Hansen, T, Wang, A G, Junkin, M, Kashaf, S S, Trusina, A & Tay, S 2022, ' Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs ', Science Advances, vol. 8, no. 35, 6240 . https://doi.org/10.1126/sciadv.abn6240
Son, M, Frank, T, Holst-Hansen, T, Wang, A G, Junkin, M, Kashaf, S S, Trusina, A & Tay, S 2022, ' Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs ', Science Advances, vol. 8, no. 35, 6240 . https://doi.org/10.1126/sciadv.abn6240
Infected cells communicate through secreted signaling molecules like cytokines, which carry information about pathogens. How differences in cytokine secretion affect inflammatory signaling over space and how responding cells decode information from p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12cfd87b9731a2a6eed3396c5610c91
https://doi.org/10.1101/2021.11.30.470463
https://doi.org/10.1101/2021.11.30.470463
Autor:
Miguel López-Botet, Aura Muntasell, Jordi Garcia-Ojalvo, Ala Trusina, Elena Abad, Thomas Holst-Hansen, Mogens H. Jensen
Allele number, or zygosity, is a clear determinant of gene expression in diploid cells. But the relationship between the number of copies of a gene and its expression can be hard to anticipate, especially when the gene in question is embedded in a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddebd0fdbcd6bd71e94c40319993ee2
Autor:
Jordi Garcia-Ojalvo, Aura Muntasell, Elena Abad, Thomas Holst-Hansen, Mogens H. Jensen, Ala Trusina, Miguel López-Botet
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
Allele number, or zygosity, is a clear determinant of gene expression in diploid cells. However, the relationship between the number of copies of a gene and its expression can be hard to anticipate, especially when the gene in question is embedded in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f47f5610b55216107364550056c19f
http://hdl.handle.net/10230/34329
http://hdl.handle.net/10230/34329