Opioid-induced bowel dysfunction in healthy volunteers assessed with questionnaires and MRI

Autor: Asbjørn Mohr Drewes, Jakob Lykke Poulsen, Christina Brock, Klaus Krogh, Matias Nilsson, Thomas Holm Sandberg, Jens Brøndum Frøkjær, Mikkel Gram

Publikováno v: Nilsson, M, Poulsen, J L, Brock, C, Sandberg, T H, Gram, M, Frøkjær, J B, Krogh, K & Drewes, A M 2016, ' Opioid-induced bowel dysfunction in healthy volunteers assessed with questionnaires and MRI ', European Journal of Gastroenterology and Hepatology, vol. 28, no. 5, pp. 514-524 . https://doi.org/10.1097/MEG.0000000000000574
Nilsson, M, Poulsen, J L, Brock, C, Sandberg, T H, Gram, M, Frøkjær, J B, Krogh, K & Drewes, A M 2016, ' Opioid-induced bowel dysfunction in healthy volunteers assessed with questionnaires and MRI ', European Journal of Gastroenterology and Hepatology, vol. 28, no. 5, pp. 514-24 . https://doi.org/10.1097/MEG.0000000000000574

OBJECTIVE: Opioid treatment is associated with numerous gastrointestinal adverse effects collectively known as opioid-induced bowel dysfunction (OIBD). Most current knowledge of the pathophysiology derives from animal studies limited by species diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4479bffd084bca57d5bff2156a8c4056
https://doi.org/10.1097/meg.0000000000000574

Established and emerging methods for assessment of small and large intestinal motility

Autor: Debbie Grønlund, Asbjørn Mohr Drewes, Adnan Madzak, Klaus Krogh, Jens Brøndum Frøkjær, Thomas Holm Sandberg, Jakob Lykke Poulsen, Anne Estrup Olesen

Publikováno v: Grønlund, D, Poulsen, J L, Sandberg, T H, Olesen, A E, Madzak, A, Krogh, K, Frøkjaer, J B & Drewes, A M 2017, ' Established and emerging methods for assessment of small and large intestinal motility ', Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, vol. 29, no. 7, e13008 . https://doi.org/10.1111/nmo.13008
Grønlund, D, Poulsen, J L, Sandberg, T H, Olesen, A E, Madzak, A, Krogh, K, Frøkjaer, J B & Drewes, A M 2017, ' Established and emerging methods for assessment of small and large intestinal motility ', Neurogastroenterology and Motility, vol. 29, no. 7, e13008 . https://doi.org/10.1111/nmo.13008

BACKGROUND: Gastrointestinal symptoms are common in the general population and may originate from disturbances in gut motility. However, fundamental mechanistic understanding of motility remains inadequate, especially of the less accessible regions o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a835ccdf4f99cb6cc5b5e4072399169
https://pure.au.dk/portal/da/publications/established-and-emerging-methods-for-assessment-of-small-and-large-intestinal-motility(1597c3bc-968e-4f3e-b4a3-f1eb96d2282f).html

The Impact of Opioid Treatment on Regional Gastrointestinal Transit

Autor: Asbjørn Mohr Drewes, Jakob Lykke Poulsen, Matias Nilsson, Christina Brock, Klaus Krogh, Thomas Holm Sandberg

Publikováno v: Poulsen, J L, Nilsson, M, Brock, C, Sandberg, T H, Krogh, K & Drewes, A M 2016, ' The Impact of Opioid Treatment on Regional Gastrointestinal Transit ', Neurogastroenterology and Motility, vol. 22, no. 2, pp. 282-291 . https://doi.org/10.5056/jnm15175
Journal of Neurogastroenterology and Motility
Poulsen, J L, Nilsson, M, Brock, C, Sandberg, T H, Krogh, K & Drewes, A M 2016, ' The Impact of Opioid Treatment on Regional Gastrointestinal Transit ', Journal of Neurogastroenterology and Motility, vol. 22, no. 2, pp. 282-91 . https://doi.org/10.5056/jnm15175

Background/Aims: To employ an experimental model of opioid-induced bowel dysfunction (OIBD) in healthy human volunteers, and evaluate the impact of opioid treatment compared to placebo on gastrointestinal (GI) symptoms and motility assessed by questi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f30626e7571ecad8c0ef92855a60b6
https://vbn.aau.dk/da/publications/caba27f8-5537-4950-b3c0-224f7f1ce1b6

A novel semi-automatic segmentation method for volumetric assessment of the colon based on magnetic resonance imaging

Autor: Asbjørn Mohr Drewes, Lasse Riis Østergaard, Thomas Holm Sandberg, Jens Brøndum Frøkjær, Matias Nilsson, Mikkel Gram, Jakob Lykke Poulsen

Publikováno v: Sandberg, T H, Nilsson, M, Poulsen, J L, Gram, M, Frøkjær, J B, Østergaard, L R & Drewes, A M 2015, ' A novel semi-automatic segmentation method for volumetric assessment of the colon based on magnetic resonance imaging ', Abdominal Imaging, vol. 40, no. 7, pp. 2232-2241 . https://doi.org/10.1007/s00261-015-0475-z
Poulsen, J L, Sandberg, T H, Nilsson, M, Gram, M, Frøkjær, J B, Østergaard, L R & Drewes, A 2015, A Novel Semi-automatic Segmentation Method for Volumetric Assessment of the Colon based on Magnetic Resonance Imaging . in Danish Society for Gastroenterology and Hepatology : 4. årsmøde ., 56, DSGH Dansk Selskab for Gastroenterologi og Hepatologi, pp. 52, Dansk Selskab for Gastroenterologi og Hepatologi, Middelfart, Denmark, 04/09/2015 .
Poulsen, J L, Sandberg, T H, Nilsson, M, Gram, M, Frøkjær, J B, Østergaard, L R & Drewes, A 2015, ' A Novel Semi-automatic Segmentation Method for Volumetric Assessment of the Colon based on Magnetic Resonance Imaging ', Neurogastroenterology and Motility, vol. 27, no. Suppl. 2, pp. 93 . https://doi.org/10.1111/nmo.12598
Aalborg University

PURPOSE: To develop a novel semi-automatic segmentation method for quantification of the colon from magnetic resonance imaging (MRI).METHODS: Fourteen abdominal T2-weighted and dual-echo Dixon-type water-only MRI scans were obtained from four healthy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3fdbaae319368eb9315c0c4a88d846
https://vbn.aau.dk/da/publications/cbc02e37-fd4e-4fee-999b-2ed8b0ec6c07