Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Thomas Hoeg"'
Autor:
Konstantinos Solomos, Victoria Tarus, Vladislav Kotek, Gaetano Invernizzi, Thomas Hoeg-Jensen
Publikováno v:
ACS Omega, Vol 7, Iss 28, Pp 24662-24668 (2022)
Externí odkaz:
https://doaj.org/article/b298dde69e8e420f9f67cfaefc09ae7c
Autor:
Thomas Kjeldsen, Wouter F. J. Hogendorf, Christian W. Tornøe, Jonathan Anderson, Frantisek Hubalek, Carsten E. Stidsen, Jan L. Sorensen, Thomas Hoeg-Jensen
Publikováno v:
ACS Omega, Vol 5, Iss 31, Pp 19827-19833 (2020)
Externí odkaz:
https://doaj.org/article/fbe8339db2cc4c5188d391217970d406
Autor:
Thomas Hoeg-Jensen
Publikováno v:
Molecular Metabolism, Vol 46, Iss , Pp 101107- (2021)
Background: Hypoglycemia, the condition of low blood sugar, is a common occurance in people with diabetes using insulin therapy. Protecting against hypoglycaemia by engineering an insulin preparation that can auto-adjust its biological activity to fl
Externí odkaz:
https://doaj.org/article/c6c11935bfc8448db10f754b548173fb
Autor:
Jason P. Pitt, Olivia M. McCarthy, Thomas Hoeg-Jensen, Benjamin M. Wellman, Richard M. Bracken
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
International charities and health care organizations advocate regular physical activity for health benefit in people with type 1 diabetes. Clinical expert and international diabetes organizations’ position statements support the management of good
Externí odkaz:
https://doaj.org/article/49e5ee2203a341369a4bfa29f8364bba
Autor:
Claire Park, Yanxian Zhang, Jae Un Jung, Line Due Buron, Nai-Pin Lin, Thomas Hoeg-Jensen, Danny Hung-Chieh Chou
Publikováno v:
Journal of Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f4a9be9b17cf4f07662d32261e4d641
https://doi.org/10.1021/acs.jmedchem.3c00280
https://doi.org/10.1021/acs.jmedchem.3c00280
Autor:
Thomas Hoeg-Jensen, Rita Slaaby, Thomas Kruse, Christian Lehn Brand, Jeppe Sturis, Christian Fledelius, Peter Nielsen, Erica Nishimura, Alice Madsen, Lennart Lykke, Kim Halskov, Simona Koscova, Vladaslav Kotek, Anthony Davis, Robert Tromans, Michael Tomsett, Guillem Penuelas-Haro, Daniel J. Leonard, Michael Orchard, Andy Chapman, Gaetano Invernizzi, Eva Johansson, Daniele Granata, Bo Hansen, Thomas Pedersen, Jonas Kildegaard, Karen Pedersen, Hanne Refsgaard, Lene Alirangis, Johannes Fels, Anita Neutzsky-Wulff, Per Sauerberg
The risk of inducing hypoglycaemia (low blood glucose) constitutes the main challenge associated with insulin therapy for diabetes. Insulin doses must be adjusted to ensure blood glucose values within normal range, but matching insulin doses to fluct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f11fc10aa8b4da1245021a1cf15e84
https://doi.org/10.21203/rs.3.rs-2882397/v1
https://doi.org/10.21203/rs.3.rs-2882397/v1
Autor:
Hanne Haahr, Thomas Kjeldsen, Peter Kurtzhals, Peter Madsen, Erica Nishimura, Thomas Hoeg-Jensen, Jeppe Sturis, Eva Johansson
Publikováno v:
Trends in Pharmacological Sciences. 42:620-639
The life-saving discovery of insulin in Toronto in 1921 is one of the most impactful achievements in medical history, at the time being hailed as a miracle treatment for diabetes. The insulin molecule itself, however, is poorly amenable as a pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64c7f2bacc0f780d68910a496ecfb8d
https://doi.org/10.1016/j.tips.2021.05.005
https://doi.org/10.1016/j.tips.2021.05.005
Autor:
Henning Hvid, Christian L. Brand, Tina Hummelshøj, Sanne Jensen, Stephan D. Bouman, Andrew Bowler, Bjarne R. Poulsen, Peter Tiainen, Thorbjörn Åkertröm, Damien Demozay, Thomas Hoeg-Jensen, Camilla Ingvorsen, Thomas Å. Pedersen, Jim McGuire, Thomas Egebjerg, Karen A. Cappelen, Ina P. Eliasen, Bo F. Hansen, Stephanie Hennen, Carsten E. Stidsen, Grith S. Olsen, Nikolaj K. Roed
Publikováno v:
Diabetologia. 66(2)
Aims/hypothesis Normalisation of blood glucose in individuals with diabetes is recommended to reduce development of diabetic complications. However, risk of severe hypoglycaemia with intensive insulin therapy is a major obstacle that prevents many in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89a9f61c32ff3fc5f78040483b515db
https://pubmed.ncbi.nlm.nih.gov/36404376
https://pubmed.ncbi.nlm.nih.gov/36404376
Autor:
Maria Pilar Ruiz Seco, José Ramón Paño Pardo, Christian Schoergenhofer, Christiane Dings, Thorsten Lehr, Felix Herth, Andriy Krendyukov, Carola Straub, Martin Kappler, Bernd Jilma, Harald Fricke, Julian Pardo, Diego de Miguel, Meinolf Thiemann, Michael Bergmann, Henning Walczak, Thomas Hoeger
Publikováno v:
EClinicalMedicine, Vol 77, Iss , Pp 102879- (2024)
Summary: Background: The phase 2 ASUNCTIS study assessed the efficacy and safety of asunercept, a fully human CD95 (Fas) ligand-binding protein, in hospitalised patients with moderate-to-severe coronavirus disease (COVID-19) to assess the clinical be
Externí odkaz:
https://doaj.org/article/f34a85026187404385bbd167989aeaf9
Autor:
Carsten Enggaard Stidsen, Jan Lindy Sorensen, Jonathan Anderson, Thomas Kjeldsen, Thomas Hoeg-Jensen, Christian Wenzel Tornøe, Frantisek Hubalek, Wouter F. J. Hogendorf
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 31, Pp 19827-19833 (2020)
ACS Omega, Vol 5, Iss 31, Pp 19827-19833 (2020)
Covalent cross-linking of biomolecules can be useful in pursuit of tissue targeting or dual targeting of two receptors on cell surfaces for avidity effects. Long linkers (>10 kDa) can be advantageous for such purposes, and poly(ethylene glycol) (PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058e5f59cc1b84c349d7aa3a7c03f8e6
https://doi.org/10.1021/acsomega.0c02712
https://doi.org/10.1021/acsomega.0c02712