Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Thomas Hart"'
Autor:
Jake X. Checketts, DO, Jared Scott, DO, Keith Fishbeck, DO, Thomas Hart, MD, William Pham, MD, Azad Dadgar, DO, Mark Calder, MD, Brent L. Norris, MD
Publikováno v:
JBJS Open Access, Vol 7, Iss 2 (2022)
Background:. Recent work has suggested good clinical and functional results with dorsal surface plating of patellar fractures. The primary outcome measurement of this study was reoperation rates for patellar fractures that had been treated with dorsa
Externí odkaz:
https://doaj.org/article/c8691ce238d5458c9c0d584a2ccca7f5
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Lyme disease is the most common tick-borne disease in North America and Europe, however, current biomarkers inconsistently detect the disease. In this issue of the JCI, Gwynne et al. revealed how the Lyme disease agent Borrelia burgdorferi relies on
Externí odkaz:
https://doaj.org/article/8cf721fe919141b1b6ce43a14173b2b1
Autor:
Douglas K. Marks, Robyn D. Gartrell, Margueritta El Asmar, Shuobo Boboila, Thomas Hart, Yan Lu, Qingfei Pan, Jiyang Yu, Hanina Hibshoosh, Hua Guo, Eleni Andreopoulou, Lisa Wiechmann, Katherine Crew, Joseph Sparano, Dawn Hershman, Eileen Connolly, Yvonne Saenger, Kevin Kalinsky
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: The PI3K/Akt/mTOR pathway in part impacts tumorigenesis through modulation of host immune activity. To assess the effects of Akt inhibition on the tumor micro-environment (TME), we analyzed tumor tissue from patients with operable hormone
Externí odkaz:
https://doaj.org/article/161752bec1d44d66a615bab9381ecca5
Autor:
Zoë Blake, Douglas K. Marks, Robyn D. Gartrell, Thomas Hart, Patti Horton, Simon K. Cheng, Bret Taback, Basil A. Horst, Yvonne M. Saenger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Abstract Background Immunotherapy, in particular checkpoint blockade, has changed the clinical landscape of metastatic melanoma. Nonetheless, the majority of patients will either be primary refractory or progress over follow up. Management of patient
Externí odkaz:
https://doaj.org/article/ce9cafdbc306493f8df22ea995ddb16b
Autor:
Thomas Hart, Ngoc Thien Thu Nguyen, Nancy A Nowak, Fuming Zhang, Robert J Linhardt, Maria Diuk-Wasser, Sanjay Ram, Peter Kraiczy, Yi-Pin Lin
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007106 (2018)
Borrelia burgdorferi sensu lato (Bbsl), the causative agent of Lyme disease, establishes an initial infection in the host's skin following a tick bite, and then disseminates to distant organs, leading to multisystem manifestations. Tick-to-vertebrate
Externí odkaz:
https://doaj.org/article/6efc2501d2174b3dacfa6a878429194a
Autor:
Patrick N. Pallier, Laura Poddighe, Virginia Zbarsky, Milosz Kostusiak, Rasall Choudhury, Thomas Hart, Miguel A. Burguillos, Omar Musbahi, Martine Groenendijk, John W. Sijben, Martijn C. deWilde, Marina Quartu, John V. Priestley, Adina T. Michael-Titus
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 504-515 (2015)
Spinal cord injury leads to major neurological impairment for which there is currently no effective treatment. Recent clinical trials have demonstrated the efficacy of Fortasyn® Connect in Alzheimer's disease. Fortasyn® Connect is a specific multi-
Externí odkaz:
https://doaj.org/article/b66cf153ae6a4af3af53313f06565da1
Autor:
Robyn Gartrell, Douglas Marks, Thomas Hart, Yan Lu, Ed Stack, Camden Esancy, Basil Horst, Yvonne Saenger, Camille Gerard, Dan Tong Jia, Paul Armenta, Daisuke Izaki, Kristen Beck
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 62-63 (2017)
OBJECTIVES/SPECIFIC AIMS: Precise biomarkers are urgently needed to characterize the tumor immune microenvironment in primary melanoma tumors both for prognostication and to predict the benefit of immuno-therapeutic intervention. The goal of this wor
Externí odkaz:
https://doaj.org/article/b40f21808f054dc9be5403bb4879ba0e
Publikováno v:
PeerJ, Vol 3, p e1045 (2015)
Maintaining ecological integrity necessitates a proactive approach of identifying and acquiring lands to conserve unfragmented landscapes, as well as evaluating existing mitigation strategies to increase connectivity in fragmented landscapes. The inc
Externí odkaz:
https://doaj.org/article/3c151b2288f44e918b37b82204c7e1a6
Autor:
Lei Xie, Xiaoxia Ge, Hepan Tan, Li Xie, Yinliang Zhang, Thomas Hart, Xiaowei Yang, Philip E Bourne
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 5, p e1003554 (2014)
Genome-Wide Association Studies (GWAS), whole genome sequencing, and high-throughput omics techniques have generated vast amounts of genotypic and molecular phenotypic data. However, these data have not yet been fully explored to improve the effectiv
Externí odkaz:
https://doaj.org/article/887eee59d8f64889bf9afcc62529e4c1
Publikováno v:
Journal of Periodontology. 94:606-615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef16d75915a1db97347826720cfe55fc
https://doi.org/10.1002/jper.22-0415
https://doi.org/10.1002/jper.22-0415