Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thomas Hannam"'
Autor:
Sa Xiao, Jason Riordon, Alex Lagunov, Mahta Ghaffarzadeh, Thomas Hannam, Reza Nosrati, David Sinton
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Human sperm compete for fertilization. Here, we find that human sperm, unexpectedly, cooperate under conditions mimicking the viscosity contrasts in the female reproductive tract. Sperm attach at the head region to migrate as a cooperative g
Externí odkaz:
https://doaj.org/article/dfbdc61e296843d4af2c5b66f10066a7
Publikováno v:
Clinical Medicine Insights: Reproductive Health, Vol 2014, Iss 8, Pp 31-36 (2014)
Externí odkaz:
https://doaj.org/article/692fe23ee89e44f0a65d4464e86e9f1d
Autor:
David Sinton, Sa Xiao, Alexander Lagunov, Mohammad Simchi, Thomas Hannam, Keith Jarvi, Reza Nosrati, Jason Riordon
Publikováno v:
Lab on a Chip. 21:775-783
The selection of high quality sperm is critical for intracytoplasmic sperm injection (ICSI), a prevalent assisted reproduction technology. However, standard selection methods are time-consuming and fail to recover the most viable sperm, thereby limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ea459399e1cad8ad16779d28a4da37
https://doi.org/10.1039/d0lc00874e
https://doi.org/10.1039/d0lc00874e
Autor:
David Sinton, Yihe Wang, Biao Zhang, Farhang Tarlan, Thomas Hannam, Keith Jarvi, Percival J. Graham, Jae Bem You, Alexander Lagunov, Jason Riordon, Tian Kong
Publikováno v:
Lab on a Chip. 19:2161-2167
Selection of high-quality sperm is critical to the success of assisted reproductive technologies. Clinical screening for top sperm has long focused on sperm swimming ability when following boundaries or when fully free of constraints. In this work, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de284bbde989b3c0997b9ecc2d9acebd
https://doi.org/10.1039/c9lc00209j
https://doi.org/10.1039/c9lc00209j
Autor:
David Sinton, Reza Nosrati, Jason Riordon, Thomas Hannam, Sa Xiao, Keith Jarvi, Yihe Wang, Mohammad Simchi, Jae Bem You, Alexander Lagunov
Publikováno v:
Lab on a chip. 21(12)
Sperm selection is essential for successful fertilization and embryo development. Current clinical sperm selection methods are labor-intensive and lack the selectivity required to isolate high-quality sperm. Microfluidic sperm selection approaches ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6160c43721213bb70364370cc4036896
https://pubmed.ncbi.nlm.nih.gov/33982043
https://pubmed.ncbi.nlm.nih.gov/33982043
Autor:
Biao Zhang, Reza Nosrati, David Sinton, Thomas Hannam, Keith Jarvi, Carlos Escobedo, Alexander Lagunov, Percival J. Graham, Jason Riordon
Publikováno v:
Nature Reviews Urology. 14:707-730
Infertility is a growing global health issue with far-reaching socioeconomic implications. A downward trend in male fertility highlights the acute need for affordable and accessible diagnosis and treatment. Assisted reproductive technologies are effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cb6f3319767ab926c0c873a0ff3661
https://doi.org/10.1038/nrurol.2017.175
https://doi.org/10.1038/nrurol.2017.175
Autor:
David Sinton, Yihe Wang, Jae Bem You, Jason Riordon, Alexander Lagunov, Brian Nguyen, Tian Kong, Junjie Zhong, Thomas Hannam, Keith Jarvi, Yi Xu
Publikováno v:
Advanced Science, Vol 6, Iss 15, Pp n/a-n/a (2019)
Advanced Science
Advanced Science
Intracytoplasmic sperm injection is a popular form of in vitro fertilization, where single sperm are selected by a clinician and injected into an egg. Whereas clinicians employ general morphology‐based guidelines to select the healthiest‐looking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044a857e42739db9c86f3081dce73878
https://doaj.org/article/3b870aca151e47599cb8cf329f5e5b41
https://doaj.org/article/3b870aca151e47599cb8cf329f5e5b41
Autor:
Yihe Wang, Scott Sanner, Jason Riordon, David Sinton, Thomas Hannam, Christopher McCallum, Jae Bem You, Alexander Lagunov, Tian Kong, Keith Jarvi
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Communications Biology
Communications Biology
Despite the importance of sperm DNA to human reproduction, currently no method exists to assess individual sperm DNA quality prior to clinical selection. Traditionally, skilled clinicians select sperm based on a variety of morphological and motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2384b5fc2f68a28de56abbd552a90300
https://doi.org/10.1038/s42003-019-0491-6
https://doi.org/10.1038/s42003-019-0491-6
Autor:
Yihe Wang, Thomas Hannam, David Sinton, Christopher McCallum, Jae Bem You, Alexander Lagunov, Farhang Tarlan, Keith Jarvi
Publikováno v:
Lab on a chip. 19(5)
There is a growing appreciation and understanding of cell-to-cell variability in biological samples. However, research and clinical practice in male fertility has relied on population, or sample-based characteristics. Single-cell resolution is partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8209863bfffcd9b869d1795a452252
https://pubmed.ncbi.nlm.nih.gov/30693362
https://pubmed.ncbi.nlm.nih.gov/30693362
Publikováno v:
Clinical Medicine Insights: Reproductive Health, Vol 2014, Iss 8, Pp 31-36 (2014)
Clinical Medicine Insights: Reproductive Health, Vol 8 (2014)
Clinical Medicine Insights. Reproductive Health
Clinical Medicine Insights: Reproductive Health, Vol 8 (2014)
Clinical Medicine Insights. Reproductive Health
Background The age-related reduction in live-birth rate is attributed to a high rate of aneuploidy and follicle depletion. We showed in an animal model that treatment with Coenzyme Q10 (CoQ10) markedly improved reproductive outcome. The aim of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf50901470c19bce85fcf68639724df5
http://www.la-press.com/coenzyme-q10-supplementation-and-oocyte-aneuploidy-in-women-undergoing-article-a4243
http://www.la-press.com/coenzyme-q10-supplementation-and-oocyte-aneuploidy-in-women-undergoing-article-a4243