Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thomas Haeufel"'
Autor:
A. David Burden, Robert Bissonnette, Alexander A. Navarini, Masamoto Murakami, Akimichi Morita, Thomas Haeufel, Binqi Ye, Frank Baehner, Tadashi Terui
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 10, Pp 2279-2297 (2023)
Abstract Introduction We evaluated the anti-interleukin-36 receptor antibody spesolimab in patients with moderate-to-severe palmoplantar pustulosis (PPP). Methods This phase IIb trial comprised a loading dose period to week (W) 4, then maintenance do
Externí odkaz:
https://doaj.org/article/6d6cb5a5aa4948e883bc5a0968cd7992
Publikováno v:
Clinical pharmacokinetics. 61(12)
The interleukin-36 signalling pathway is associated with pathogenesis of a number of inflammatory diseases. Spesolimab is a selective, humanised, IgG1 antibody that targets the interleukin-36 receptor. We aimed to evaluate the pharmacokinetics, safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82d1a070e29e5b5271aea1950c0362e
https://pubmed.ncbi.nlm.nih.gov/36451029
https://pubmed.ncbi.nlm.nih.gov/36451029
Autor:
Marc Ferrante, Peter M Irving, Christian P Selinger, Geert D’Haens, Tanja Kuehbacher, Ursula Seidler, Savion Gropper, Thomas Haeufel, Sebastiano Forgia, Silvio Danese, Jochen Klaus, Brian G. Feagan
Publikováno v:
Expert opinion on drug safety.
BACKGROUND: Interleukin (IL)-36 signaling has been shown to be increased in ulcerative colitis (UC). Spesolimab, a novel humanized monoclonal antibody, targets the IL-36 pathway. RESEARCH DESIGN AND METHODS: We report safety, immunogenicity, and effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46314292b15ef030e41b6997f5a1462
https://pubmed.ncbi.nlm.nih.gov/35861588
https://pubmed.ncbi.nlm.nih.gov/35861588
Publikováno v:
The Spine Journal. 9:98S-99S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577f47f15b57c12b68e3768d787a25c1
https://doi.org/10.1016/j.spinee.2009.08.229
https://doi.org/10.1016/j.spinee.2009.08.229