Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thomas H. McLean"'
Autor:
Michael R. Braden, Jason C. Parrish, Deborah M. Kurrasch-Orbaugh, Thomas H. McLean, James J. Chambers, David E. Nichols, Danuta Marona-Lewicka
Publikováno v:
Journal of Medicinal Chemistry. 49:4269-4274
A conformationally restricted analogue of mescaline, C-(4,5,6-trimethoxyindan-1-yl)-methanamine, was designed using a 5-HT(2A) receptor homology model. The compound possessed 3-fold higher affinity and potency than and efficacy equal to that of mesca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b721edbef86b9379632fb57c9f1f373
https://doi.org/10.1021/jm060272y
https://doi.org/10.1021/jm060272y
Autor:
Miguel Reyes-Parada, Thomas H. McLean, David E. Nichols, Mariano Castillo, Bruce K. Cassels, Alejandra Gallardo-Godoy, Angélica Fierro
Publikováno v:
Journal of Medicinal Chemistry. 48:2407-2419
A series of phenethylamine derivatives with various ring substituents and with or without N-methyl and/or C-alpha methyl or ethyl groups was synthesized and assayed for their ability reversibly to inhibit monoamine oxidase A (MAO-A) and monoamine oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c39f3774aad2a82ccea4204e3d14ee
https://doi.org/10.1021/jm0493109
https://doi.org/10.1021/jm0493109
Autor:
Thomas H. McLean, and Alejandra Gallardo-Godoy, Jason C. Parrish, Danuta Marona-Lewicka, David E. Nichols, Michael R. Braden
Publikováno v:
Journal of medicinal chemistry. 49(19)
A series of conformationally restricted analogues of the hallucinogenic phenethylamine 1 (2,5-dimethoxy-4-bromophenethylamine, 2C-B) was synthesized to test several hypotheses concerning the bioactive conformation of phenethylamine ligands upon bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b88cc750148409e8352b27fdfd07c42
https://pubmed.ncbi.nlm.nih.gov/16970404
https://pubmed.ncbi.nlm.nih.gov/16970404