Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas H. Knight"'
Autor:
Daniel C. Douek, Thomas H. Knight, Emily Tsuchida, Netanya G. Sandler, Tammy Yotter, David M. Asmuth, Juan Carlos Garcia, Christopher J. Miller, Neil M. Flynn, Tsung Teh Wu, Anthony Albanese, Zhong-Min Ma, Sridevi Devaraj
Publikováno v:
AIDS (London, England), vol 27, iss 14
AIDS (London, England)
AIDS (London, England)
Objectives: To examine the impact of serum-derived bovine immunoglobulin, an oral medical food known to neutralize bacterial antigen and reduce intestinal inflammation, on restoration of mucosal immunity and gastrointestinal function in individuals w
Autor:
Tammy Yotter, David M. Asmuth, Delandy H. McConnell, Barbara L. Shacklett, Bridget McLaughlin, Timothy L. Hayes, Thomas H. Knight, Juan Carlos Garcia, Richard B. Pollard, J. William Critchfield
Publikováno v:
AIDS. 27:867-877
OBJECTIVE The objective of this study was to assess the effects of HAART initiation on CD4(+) T-cell repopulation and T-cell immune activation in rectal and duodenal mucosa. DESIGN The effects of HAART on the gastrointestinal tract remain controversi
Autor:
Paolo Troia-Cancio, Collin L. Ellis, Heather A. Overman, Richard B. Pollard, Thomas H. Knight, David M. Asmuth, Christopher J. Miller, Chin-Shang Li, Tammy Yotter, Zhong-Min Ma, Jian Wu, John C. Rutledge, Archana Maniar, Surinder K Mann, Anthony Albanese, Natalie J. Török, Timothy L. Hayes
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 57:363-370
Background The relationship between gut microbial community composition at the higher-taxonomic order level and local and systemic immunologic abnormalities in HIV disease may provide insight into how bacterial translocation impacts HIV disease. Meth
Autor:
Francesco Pollaro, Sudesh P Makker, Angela Ostuni, Thomas H. Knight, Alfonso Bavoso, Alfonso Tramontano, Jolanda De Vendel, Francesca Armentano
Publikováno v:
Journal of Peptide Science. 12:843-849
Introduction of aldehyde groups into protein conjugates enhanced the immune response to a coupled peptide without the use of strong adjuvants. Synthetic peptides representing the N-terminal (residues 1-16) and internal (residues 53-65) epitopes of to
Autor:
Zhong-Min Ma, Timothy L. Hayes, David M. Asmuth, Richard B. Pollard, Paolo Troia-Cancio, Christopher J. Miller, Tammy Yotter, Anthony Albanese, Surinder K Mann, Thomas H. Knight, Gregory P. Melcher
Publikováno v:
AIDS (London, England). 26(13)
Objectives To examine immune restoration in duodenal tissue and correlates of reduction of immune activation in chronic HIV-infected patients randomized to different treatment regimens. Design Randomized clinical trial (RCT) comparing raltegravir to
Autor:
Thomas H. Knight, Mark A. Winters, David M. Asmuth, Mark Holodniy, Robert Eisen, Aarthi Chary
Publikováno v:
Journal of medical virology. 84(3)
Peripheral blood mononuclear cells (PBMCs) represent an extrahepatic hepatitis C virus (HCV) reservoir, the significance of which is unclear due to limited studies and varying test methodologies. In this study, a commercial viral load assay for measu
Publikováno v:
Journal of the American Society of Nephrology : JASN. 17(7)
It was shown previously that an N-terminal fragment (nM60) that encompasses amino acid residues 1 to 563 of megalin could induce active Heymann nephritis (AHN) as efficiently as the native protein. For delineation of a minimal structure within this f
Publikováno v:
Immunology letters. 103(1)
Covalent interactions between antibody combining site residues and substrates have been implicated in the catalytic activity of abzymes elicited by design or occurring naturally in autoimmune disease. In this study, the potential for covalent binding
Autor:
David M. Asmuth, Xiao Dong Li, Paolo Troia-Cancio, Jonathan A. Eisen, Christopher J. Miller, Chin-Shang Li, Collin L. Ellis, Tammy Yotter, Richard B. Pollard, Amber L. Hartman, Zhong-Min Ma, Surinder K Mann, Anthony Albanese, Javeed Siddiqui, John C. Rutledge, Heather A. Overman, Thomas H. Knight, Gregory P. Melcher
Publikováno v:
Gastroenterology. 138:S-749
thy) and histologic (epithelial erosions, crypt hyperplasia, mononuclear cellular infiltrate) lesions were inversely associated with changes in composition of the intestinal microbiota of IL-10-/mice at all time points. Conclusions: Changes in the re