Výsledky vyhledávání - "Thomas H. Haak"

Akademický článek

Treatment of rheumatoid arthritis with baricitinib or upadacitinib is associated with reduced scaffold protein NEDD9 levels in CD4+ T cells

Autor: Viktoria Golumba‐Nagy, Shuaifeng Yan, Eva Steinbach‐Knödgen, Jan Thiele, Ruth L. Esser, Thomas H. Haak, Anastasia Nikiforov, Anja Meyer, Tamina Seeger‐Nukpezah, David M. Kofler

Publikováno v: Physiological Reports, Vol 11, Iss 19, Pp n/a-n/a (2023)

Abstract The JAK/STAT pathway plays a crucial role in the pathogenesis of rheumatoid arthritis (RA) and JAK inhibitors have emerged as a new group of effective drugs for RA treatment. Recently, high STAT3 levels have been associated with the upregula

Externí odkaz: https://doaj.org/article/81438bdbe9c5496dade440d63be182ff

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Regulatory T cell frequencies in patients with rheumatoid arthritis are increased by conventional and biological DMARDs but not by JAK inhibitors

Autor: David M. Kofler, Konstantin Kotschenreuther, Joanna Schiller, Julia von Tresckow, Paula S. Wittekind, Thomas H Haak, Anja Meyer

Publikováno v: Annals of the Rheumatic Diseases. 80:e196-e196

Regulatory T (Treg) cells play an important role in controlling immune responses. Their frequency is decreased in many autoimmune diseases, including rheumatoid arthritis (RA). We read with great interest the article by Rosenzwajg et al which present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22272f00fd4b7f7d3786597375a7c3a1
https://doi.org/10.1136/annrheumdis-2019-216576

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