Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Thomas H Hostetter"'
Autor:
Tariq Shafi, Timothy W Meyer, Thomas H Hostetter, Michal L Melamed, Rulan S Parekh, Seungyoung Hwang, Tanushree Banerjee, Josef Coresh, Neil R Powe
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126048 (2015)
Numerous substances accumulate in the body in uremia but those contributing to cardiovascular morbidity and mortality in dialysis patients are still undefined. We examined the association of baseline free levels of four organic solutes that are secre
Externí odkaz:
https://doaj.org/article/665dfccb0aa34c9fb68c22a9723fb1cc
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143731 (2015)
Large size, protein binding and intracellular sequestration are well known to limit dialytic removal of compounds. In studying the normal renal and dialytic handling of trimethylamine oxide (TMAO), a molecule associated with cardiovascular disease in
Externí odkaz:
https://doaj.org/article/5a22416218fe411e96378817f2ca693f
Autor:
Camille R. Brightwell, Ameya S. Kulkarni, William Paredes, Kehao Zhang, Jaclyn B. Perkins, Knubian J. Gatlin, Matthew Custodio, Hina Farooq, Bushra Zaidi, Rima Pai, Rupinder S. Buttar, Yan Tang, Michal L. Melamed, Thomas H. Hostetter, Jeffrey E. Pessin, Meredith Hawkins, Christopher S. Fry, Matthew K. Abramowitz
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
BACKGROUND Skeletal muscle maladaptation accompanies chronic kidney disease (CKD) and negatively affects physical function. Emphasis in CKD has historically been placed on muscle fiber–intrinsic deficits, such as altered protein metabolism and atro
Externí odkaz:
https://doaj.org/article/28e2b2ab95fc4aababe1574c610d359a
Publikováno v:
Environmental Toxicology and Pharmacology. 100:104142
Publikováno v:
Expert Review of Clinical Pharmacology. 14:1173-1182
Background: Arsenic trioxide (ATO) was successfully applied to treat acute promyelocytic leukemia (APL).Methods: Inorganic arsenic (iAs), monomethylarsonic acid (MMAV) and dimethyarsinic acid (DMAV) in plasma of 143 APL patients with different renal
Autor:
Thomas H. Hostetter, Timothy W. Meyer
Publikováno v:
Clin J Am Soc Nephrol
The high GFR in vertebrates obligates large energy expenditure. Homer Smith’s teleologic argument that this high GFR was needed to excrete water as vertebrates evolved in dilute seas is outdated. The GFR is proportional to the metabolic rate among
Publikováno v:
Clinical Journal of the American Society of Nephrology. 17:1800-1801
Autor:
Jennifer E. Flythe, Magdalene M. Assimon, Matthew J. Tugman, Julia H. Narendra, Simran K. Singh, Wanting Jin, Quefeng Li, Nisha Bansal, Thomas H. Hostetter, Laura M. Dember
Publikováno v:
Kidney international reports. 7(10)
Diuretic use may reduce volume-related complications in hemodialysis. We evaluated the efficacy, safety, and tolerability of furosemide in patients with hemodialysis-dependent kidney failure.We conducted an open label, single-arm, 18-week, dose titra
Autor:
William Paredes, Suman M. Reddy, Matthew Custodio, Robert I. Lynn, Thomas H. Hostetter, Narender Goel, Sarah Park, Anusha Bandla, Deepak Sapkota, Matthew K. Abramowitz
Publikováno v:
Am J Physiol Renal Physiol
The use of high dialysate bicarbonate for hemodialysis in end-stage renal disease is associated with increased mortality, but potential physiological mediators are poorly understood. Alkalinization due to high dialysate bicarbonate may stimulate orga
Autor:
Melissa D. Zullo, Mahboob Rahman, Thomas H. Hostetter, Sanjay Rajagopalan, Mirela Dobre, Anuja Sarode, Sadeer G. Al-Kindi
Publikováno v:
Mayo Clin Proc
Objective To assess the association between serum bicarbonate concentration and cause-specific mortality in the US general population. Methods A total of 31,195 individuals enrolled in the National Health and Nutrition Examination Survey between 1999