Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Thomas Höfken"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15916 (2023)
The p21-activated kinases (PAKs) are important signaling proteins. They contribute to a surprisingly wide range of cellular processes and play critical roles in a number of human diseases including cancer, neurological disorders and cardiac diseases.
Externí odkaz:
https://doaj.org/article/b523b0c0e7214a22956606c9293b1d13
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 4, p 772 (2017)
Zinc cluster proteins are a large family of transcriptional regulators with a wide range of biological functions. The zinc cluster proteins Ecm22, Upc2, Sut1 and Sut2 have initially been identified as regulators of sterol import in the budding yeast
Externí odkaz:
https://doaj.org/article/4c786861922f49858aabc1030c9edca4
Ecm22 and Upc2 regulate yeast mating through control of expression of the mating genes PRM1 and PRM4
Autor:
Thomas Höfken
Publikováno v:
Biochemical and Biophysical Research Communications. 493:1485-1490
Budding yeast mating is an excellent model for receptor-activated cell differentiation. Here we identify the related transcription factors Ecm22 and Upc2 as novel regulators of mating. Cells lacking both ECM22 and UPC2 display strong mating defects w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4caa1c963a3422c8a5027310c7e0c81
https://doi.org/10.1016/j.bbrc.2017.10.005
https://doi.org/10.1016/j.bbrc.2017.10.005
©2019 The Authors. p21-activated kinases (PAKs) are important signalling molecules with a wide range of functions. In budding yeast, the main PAKs Ste20 and Cla4 regulate the response to hyperosmotic stress, which is an excellent model for the adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18117998aa8d06f20c2c294479a657d0
https://bura.brunel.ac.uk/handle/2438/18920
https://bura.brunel.ac.uk/handle/2438/18920
Publikováno v:
Eukaryotic Cell. 11:442-451
In the budding yeast Saccharomyces cerevisiae , the Cdc42 effector Ste20 plays a crucial role in the regulation of filamentous growth, a response to nutrient limitation. Using the split-ubiquitin technique, we found that Ste20 forms a complex with Vm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2e292a40f126668b66aed9570d91a5
https://doi.org/10.1128/ec.05286-11
https://doi.org/10.1128/ec.05286-11
Publikováno v:
FEBS Journal. 276:7253-7264
The conserved Rho-type GTPase Cdc42p is a key regulator of signal transduction and polarity in eukaryotic cells. In the yeast Saccharomyces cerevisiae, Cdc42p promotes polarized growth through the p21-activated kinases Ste20p and Cla4p. Previously, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::261627f9567dbc7892c8d49945475914
https://doi.org/10.1111/j.1742-4658.2009.07433.x
https://doi.org/10.1111/j.1742-4658.2009.07433.x
Publikováno v:
Mol Biol Cell
© 2009 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,. the appearance of) the edited manuscript in an online issue of MBoC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd2e1649cedb7929e735f3debb53c26
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777111/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777111/
Publikováno v:
Journal of Cell Science. 120:3613-3624
The Saccharomyces cerevisiae p21-activated kinase (PAK) Ste20 regulates various aspects of cell polarity during vegetative growth, mating and filamentous growth. To gain further insight into the mechanisms of Ste20 action, we screened for interactors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6dd5485a2df1c58382b115d86d1249
https://doi.org/10.1242/jcs.009860
https://doi.org/10.1242/jcs.009860
Autor:
Kelly, Woods, Thomas, Höfken
Publikováno v:
Molecular microbiology. 99(3)
The transition between a unicellular yeast form to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fungal pathogens such as Candida albicans. Here, we examine the role of the related transcription factors Ec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ecb1c41adb66ddd094262f678957e17
https://pubmed.ncbi.nlm.nih.gov/26448198
https://pubmed.ncbi.nlm.nih.gov/26448198
Publikováno v:
Biochemical and Biophysical Research Communications. 276:680-685
Mitogen-activated protein kinase (MAPK) family members such as c-jun N-terminal kinase (JNK) may act as signal transducers early during pancreatitis development and evidence indicates that MAPK phosphatases (MKP) downregulate MAPK. We therefore inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3123644f1a523a78b5facf20cd6a5ed0
https://doi.org/10.1006/bbrc.2000.3530
https://doi.org/10.1006/bbrc.2000.3530