Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Thomas Grevesse"'
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Background The Arctic Ocean receives massive freshwater input and a correspondingly large amount of humic-rich organic matter of terrestrial origin. Global warming, permafrost melt, and a changing hydrological cycle will contribute to an int
Externí odkaz:
https://doaj.org/article/1cf3204967a5495fa4d28d36e7f84723
Autor:
Jorge A Jimenez, Kevin Kit Parker, Blakely B. O'Connor, Philip Demokritou, Dimitrios Bitounis, Herdeline Ann M. Ardoña, John F. Zimmerman, Thomas Grevesse
Publikováno v:
Integr Biol (Camb)
The blood–brain barrier plays a critical role in delivering oxygen and nutrients to the brain while preventing the transport of neurotoxins. Predicting the ability of potential therapeutics and neurotoxicants to modulate brain barrier function rema
Autor:
Anna Herland, Ben Swenor, Daniel Levner, Olivier Y.F. Henry, Sasan Jalili-Firoozinezhad, Angeliki Chalkiadaki, Henry Sanchez, Andrzej Przekwas, Sauveur S. F. Jeanty, Rachelle Prantil-Baun, Josiah Sliz, Youngjae Choe, Kyung-Jin Jang, Moran Yadid, Susan Marquez, Chris Hinojosa, Thomas C. Ferrante, Blakely B. O'Connor, Tiama Hamkins-Indik, Rachel Fleming, Stephanie Dauth, Janna Nawroth, Morgan Burt, Ben M. Maoz, David B. Chou, Aaron Delahanty, John P. Ferrier, Anthony Bahinski, Jose Fernandez-Alcon, Bret Nestor, Guy Robert Thompson, Lian Leng, Robert Mannix, Michael J. Cronce, Yuka Milton, Mahadevabharath R. Somayaji, Alexandra Sontheimer-Phelps, Tae-Eun Park, Miles Ingram, Edward A. FitzGerald, Debarun Das, Ville J. Kujala, Josue A. Goss, George J. Touloumes, Toni Divic, Carlos F. Ng, Oren Levy, Zachary Tranchemontagne, Elizabeth Calamari, Geraldine A. Hamilton, Alexander Cho, Thomas Grevesse, Norman Wen, Tessa Huffstater, Donald E. Ingber, Kevin Kit Parker, Richard M. Novak
Publikováno v:
Nature Biomedical Engineering. 4:407-420
Organ chips can recapitulate organ-level (patho)physiology, yet pharmacokinetic and pharmacodynamic analyses require multi-organ systems linked by vascular perfusion. Here, we describe an 'interrogator' that employs liquid-handling robotics, custom s
Autor:
Alexander Cho, Kevin L. Shores, Anna Herland, Donald E. Ingber, Janna Nawroth, Edward A. FitzGerald, Charles Vidoudez, Thomas Grevesse, Kevin Kit Parker, Sean P. Sheehy, Stephanie Dauth, Daniel Segrè, Ben M. Maoz, Tae-Eun Park, Robert Mannix, Nikita Budnik, Alan R. Pacheco, Bogdan Budnik
Publikováno v:
Nat Biotechnol
The neurovascular unit (NVU) regulates metabolic homeostasis as well as drug pharmacokinetics and pharmacodynamics in the central nervous system. Metabolic fluxes and conversions over the NVU rely on interactions between brain microvascular endotheli
Autor:
Seungkuk Ahn, Blakely B. O'Connor, John F. Zimmerman, Feyisayo Eweje, Dimitrios Bitounis, Thomas Grevesse, Kevin Kit Parker, Philip Demokritou, Herdeline Ann M. Ardoña, Karla N. Rivera
Publikováno v:
Nanoscale
Engineered nanomaterials (ENMs) are increasingly used in consumer products due to their unique physicochemical properties, but the specific hazards they pose to the structural and functional integrity of endothelial barriers remain elusive. When asse
Autor:
Nikita Budnik, Robert Mannix, Sean P. Sheehy, Thomas Grevesse, Donald E. Ingber, Stephanie Dauth, Kevin Kit Parker, Charles Vidoudez, Anna Herland, Bogdan Budnik, Edward A. FitzGerald, Ben M. Maoz
Publikováno v:
Advanced biosystems. 4(9)
The functional state of the neurovascular unit (NVU), composed of the blood-brain barrier and the perivasculature that forms a dynamic interface between the blood and the central nervous system (CNS), plays a central role in the control of brain home
Autor:
Ben M. Maoz, Sasan Jalili-Firoozinezhad, Andrzej Przekwas, Carlos F. Ng, Alexander Cho, Anna Herland, Jose Fernandez-Alcon, Daniel Levner, Olivier Y.F. Henry, Janna Nawroth, Blakely B. O'Connor, Debarun Das, David B. Chou, Kevin Kit Parker, Anthony Bahinski, Morgan Burt, Ville J. Kujala, Susan Clauson, Mahadevabharath R. Somayaji, Thomas C. Ferrante, Ben Swenor, Henry Sanchez, Lian Leng, Tessa Huffstater, Angeliki Chalkiadaki, Miles Ingram, Donald E. Ingber, Tiama Hamkins-Indik, Norman Wen, Rachelle Prantil-Baun, Youngjae Choe, Josiah Sliz, Zachary Tranchemontagne, Bret Nestor, George J. Touloumes, Rachel Fleming, Guy Robert Thompson, Alexandra Sontheimer-Phelps, Josue A. Goss, Oren Levy, Toni Divic, Elizabeth Calamari, Sauveur S. F. Jeanty, Kyung-Jin Jang, Michael J. Cronce, Yuka Milton, Richard M. Novak, Geraldine A. Hamilton, Thomas Grevesse, Chris Hinojosa, Moran Yadid, Stephanie Dauth, John P. Ferrier, Tae-Eun Park, Robert Mannix, Edward A. FitzGerald, Aaron Delahanty
Publikováno v:
Nat Biomed Eng
Here we describe of an ‘Interrogator’ instrument that uses liquid-handling robotics, a custom software package, and an integrated mobile microscope to enable automated culture, perfusion, medium addition, fluidic linking, sample collection, andin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91904c828996f1d91cb14b8c52e98514
https://doi.org/10.1101/569541
https://doi.org/10.1101/569541
Autor:
Harry Pantazopoulos, Patrick H. Campbell, Stephanie Dauth, Kevin Kit Parker, Sabina Berretta, Ben M. Maoz, Thomas Grevesse
Publikováno v:
Journal of Comparative Neurology. 524:1309-1336
In the brain, extracellular matrix (ECM) components form networks that contribute to structural and functional diversity. Maladaptive remodeling of ECM networks has been reported in neurodegenerative and psychiatric disorders, suggesting that the bra
Autor:
Geoffrey Delhaye, Marie Versaevel, Danahe Mohammed, Sylvain Gabriele, Joséphine Lantoine, Thomas Grevesse, Maryam Riaz
Publikováno v:
médecine/sciences. 32:146-149
Autor:
Maryam Riaz, Thomas Grevesse, Tobias Corne, Danahe Mohammed, Céline Bruyère, Laura Alaimo, Joséphine Lantoine, Winnok H. De Vos, Sylvain Gabriele, Marie Versaevel
Publikováno v:
Cell adhesion & migration
The mechanical properties of living cells reflect their propensity to migrate and respond to external forces. Both cellular and nuclear stiffnesses are strongly influenced by the rigidity of the extracellular matrix (ECM) through reorganization of th